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Reconciling a gene tree with a species tree is an important task that reveals much about the evolution of genes, genomes, and species, as well as about the molecular function of genes. A wide array of computational tools have been devised…

Populations and Evolution · Quantitative Biology 2012-12-11 Yun Yu , Luay Nakhleh

The maximum likelihood threshold (MLT) of a graph $G$ is the minimum number of samples to almost surely guarantee existence of the maximum likelihood estimate in the corresponding Gaussian graphical model. We give a new characterization of…

Many statistical models in cosmology can be simulated forwards but have intractable likelihood functions. Likelihood-free inference methods allow us to perform Bayesian inference from these models using only forward simulations, free from…

Cosmology and Nongalactic Astrophysics · Physics 2018-04-11 Justin Alsing , Benjamin Wandelt , Stephen Feeney

Phylogenetic diversity is a measure for describing how much of an evolutionary tree is spanned by a subset of species. If one applies this to the (unknown) subset of current species that will still be present at some future time, then this…

Subcellular Processes · Quantitative Biology 2009-09-29 Beata Faller , Fabio Pardi , Mike Steel

Most of major algorithms for phylogenetic tree reconstruction assume that sequences in the analyzed set either do not have any offspring, or that parent sequences can maximally mutate into just two descendants. The graph resulting from such…

Populations and Evolution · Quantitative Biology 2013-10-09 Piotr Plonski , Jan P. Radomski

Phylogenetic networks provide a means of describing the evolutionary history of sets of species believed to have undergone hybridization or gene flow during their evolution. The mutation process for a set of such species can be modeled as a…

Populations and Evolution · Quantitative Biology 2022-11-23 Travis Barton , Elizabeth Gross , Colby Long , Joseph Rusinko

Historical linguistics aims at inferring the most likely language phylogenetic tree starting from information concerning the evolutionary relatedness of languages. The available information are typically lists of homologous (lexical,…

Physics and Society · Physics 2015-05-27 Simone Pompei , Vittorio Loreto , Francesca Tria

Constrained approaches to maximum likelihood estimation in the context of finite mixtures of normals have been presented in the literature. A fully data-dependent constrained method for maximum likelihood estimation of clusterwise linear…

Methodology · Statistics 2016-11-11 Roberto Di Mari , Roberto Rocci , Stefano Antonio Gattone

The reconstruction of a species phylogeny from genomic data faces two significant hurdles: 1) the trees describing the evolution of each individual gene--i.e., the gene trees--may differ from the species phylogeny and 2) the molecular…

Machine Learning · Computer Science 2017-07-17 Gautam Dasarathy , Elchanan Mossel , Robert Nowak , Sebastien Roch

Bayesian analysis plays a crucial role in estimating distribution of unknown parameters for given data and model. Due to the curse of dimensionality, it becomes difficult for high-dimensional problems, especially when multiple modes exist.…

Methodology · Statistics 2025-07-18 Zihan Liao , Binbin Li , Hua-Ping Wan

Information spreads across social and technological networks, but often the network structures are hidden from us and we only observe the traces left by the diffusion processes, called cascades. Can we recover the hidden network structures…

Social and Information Networks · Computer Science 2014-05-14 Hadi Daneshmand , Manuel Gomez-Rodriguez , Le Song , Bernhard Schoelkopf

One of the main aims of phylogenetics is the reconstruction of the correct evolutionary tree when data concerning the underlying species set are given. These data typically come in the form of DNA, RNA or protein alignments, which consist…

Populations and Evolution · Quantitative Biology 2019-03-22 Mareike Fischer

Our work introduces an approach for estimating the contribution of attachment mechanisms to the formation of growing networks. We present a generic model in which growth is driven by the continuous attachment of new nodes according to…

Probability · Mathematics 2019-02-20 Jan Medina , Jorge Finke , Camilo Rocha

Complex networks hosting binary-state dynamics arise in a variety of contexts. In spite of previous works, to fully reconstruct the network structure from observed binary data remains to be challenging. We articulate a statistical inference…

Physics and Society · Physics 2018-03-14 Chuang Ma , Han-Shuang Chen , Ying-Cheng Lai , Hai-Feng Zhang

Survival analysis is a widely-used technique for analyzing time-to-event data in the presence of censoring. In recent years, numerous survival analysis methods have emerged which scale to large datasets and relax traditional assumptions…

Machine Learning · Computer Science 2023-11-06 Mert Ketenci , Shreyas Bhave , Noémie Elhadad , Adler Perotte

Phylogenetic networks are often constructed by merging multiple conflicting phylogenetic signals into a directed acyclic graph. It is interesting to explore whether a network constructed in this way induces biologically-relevant…

Populations and Evolution · Quantitative Biology 2017-07-13 Steven Kelk , Fabio Pardi , Celine Scornavacca , Leo van Iersel

Quantitative methods for studying biodiversity have been traditionally rooted in the classical theory of finite frequency tables analysis. However, with the help of modern experimental tools, like high throughput sequencing, we now begin to…

Methodology · Statistics 2015-12-22 Maciej Pietrzak , Grzegorz A. Rempała , Michał Seweryn , Jacek Wesołowski

Implementing Bayesian inference is often computationally challenging in applications involving complex models, and sometimes calculating the likelihood itself is difficult. Synthetic likelihood is one approach for carrying out inference…

Computation · Statistics 2021-03-15 David T. Frazier , David J. Nott , Christopher Drovandi , Robert Kohn

A phylogenetic tree is an important way in Bioinformatics to find the evolutionary relationship among biological species. In this research, a proposed model is described for the estimation of a phylogenetic tree for a given set of data. To…

Populations and Evolution · Quantitative Biology 2025-09-03 S M Rafiuddin

Likelihood-free methods are useful for parameter estimation of complex models with intractable likelihood functions for which it is easy to simulate data. Such models are prevalent in many disciplines including genetics, biology, ecology…

Methodology · Statistics 2022-03-29 Christopher Drovandi , David T Frazier