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Phylogenetic networks extend phylogenetic trees to allow for modeling reticulate evolutionary processes such as hybridization. They take the shape of a rooted, directed, acyclic graph, and when parameterized with evolutionary parameters,…

Populations and Evolution · Quantitative Biology 2018-08-28 R. A. L. Elworth , H. A. Ogilvie , J. Zhu , L. Nakhleh

We study probability density functions that are log-concave. Despite the space of all such densities being infinite-dimensional, the maximum likelihood estimate is the exponential of a piecewise linear function determined by finitely many…

Seemingly unrelated regressions are statistical regression models based on the Gaussian distribution. They are popular in econometrics but also arise in graphical modeling of multivariate dependencies. In maximum likelihood estimation, the…

Statistics Theory · Mathematics 2007-06-13 Mathias Drton

Random feature methods have been successful in various machine learning tasks, are easy to compute, and come with theoretical accuracy bounds. They serve as an alternative approach to standard neural networks since they can represent…

Machine Learning · Statistics 2026-01-21 Abolfazl Hashemi , Hayden Schaeffer , Robert Shi , Ufuk Topcu , Giang Tran , Rachel Ward

Phylogenetic trees are the fundamental mathematical representation of evolutionary processes in biology. They are also objects of interest in pure mathematics, such as algebraic geometry and combinatorics, due to their discrete geometry.…

Metric Geometry · Mathematics 2022-07-01 Anthea Monod , Bo Lin , Ruriko Yoshida , Qiwen Kang

We consider the question of existence of a unique invariant probability distribution which satisfies some evolutionary property. The problem arises from the random graph theory but to answer it we treat it as a dynamical system in the…

Dynamical Systems · Mathematics 2016-09-07 David Gamarnik , Tomasz Nowicki , Grzegorz Swirszcz

Phylogenetic networks generalise phylogenetic trees and allow for the accurate representation of the evolutionary history of a set of present-day species whose past includes reticulate events such as hybridisation and lateral gene transfer.…

Populations and Evolution · Quantitative Biology 2018-09-05 Joan Carles Pons , Charles Semple , Mike Steel

For a phylogenetic tree, the phylogenetic diversity of a set A of taxa is the total weight of edges on paths to A. Finding small sets of maximal diversity is crucial for conservation planning, as it indicates where limited resources can be…

Data Structures and Algorithms · Computer Science 2025-10-29 Mark Jones , Jannik Schestag

Density functional theory underlies the most successful and widely used numerical methods for electronic structure prediction of solids. However, it has the fundamental shortcoming that the universal density functional is unknown. In…

Disordered Systems and Neural Networks · Physics 2020-09-23 M. Michael Denner , Mark H. Fischer , Titus Neupert

We establish a log-supermodularity property for probability distributions on binary patterns observed at the tips of a tree that are generated under any 2--state Markov process. We illustrate the applicability of this result in…

Populations and Evolution · Quantitative Biology 2008-05-21 Mike Steel , Beata Faller

Time-series of allele frequencies are a useful and unique set of data to determine the strength of natural selection on the background of genetic drift. Technically, the selection coefficient is estimated by means of a likelihood function…

Populations and Evolution · Quantitative Biology 2016-08-23 Angelo Valleriani

In this paper we introduce a method for resolving multi-parameter likelihoods by fixing all parameter values, but two. Evaluation of those two variables is followed by iteratively cycling through each of the parameters in turn until…

Instrumentation and Methods for Astrophysics · Physics 2025-09-10 Joel S. Jayson

This article presents an algebraic topology perspective on the problem of finding a complete coverage probability of a one dimensional domain $X$ by a random covering, and develops techniques applicable to the problem beyond the one…

Algebraic Topology · Mathematics 2015-09-11 Rafal Komendarczyk , Jeffrey Pullen

We propose a methodology for testing linear hypothesis in high-dimensional linear models. The proposed test does not impose any restriction on the size of the model, i.e. model sparsity or the loading vector representing the hypothesis.…

Methodology · Statistics 2019-07-09 Yinchu Zhu , Jelena Bradic

We investigate the optimization landscape of maximum likelihood estimation (MLE) for the Cavender-Farris-Neyman (CFN) model, a two-state latent tree model fundamental to statistical phylogenetics and the ferromagnetic Ising model. Although…

Statistics Theory · Mathematics 2026-05-22 David Clancy , Hanbaek Lyu , Sebastien Roch

Given a collection $\tau$ of subsets of a finite set $X$, we say that $\tau$ is {\em phylogenetically flexible} if, for any collection $R$ of rooted phylogenetic trees whose leaf sets comprise the collection $\tau$, $R$ is compatible (i.e.…

Combinatorics · Mathematics 2018-01-15 Katharina T. Huber , Vincent Moulton , Mike Steel

We consider 1-dimensional location estimation, where we estimate a parameter $\lambda$ from $n$ samples $\lambda + \eta_i$, with each $\eta_i$ drawn i.i.d. from a known distribution $f$. For fixed $f$ the maximum-likelihood estimate (MLE)…

Statistics Theory · Mathematics 2022-07-20 Shivam Gupta , Jasper C. H. Lee , Eric Price , Paul Valiant

In this work, we consider the approximate reconstruction of high-dimensional periodic functions based on sampling values. As sampling schemes, we utilize so-called reconstructing multiple rank-1 lattices, which combine several preferable…

Numerical Analysis · Mathematics 2019-05-14 Lutz Kämmerer , Toni Volkmer

We introduce a generalized additive model for location, scale, and shape (GAMLSS) next of kin aiming at distribution-free and parsimonious regression modelling for arbitrary outcomes. We replace the strict parametric distribution…

Methodology · Statistics 2023-12-21 Sandra Siegfried , Lucas Kook , Torsten Hothorn

It is well-known that the parameterized family of functions representable by fully-connected feedforward neural networks with ReLU activation function is precisely the class of piecewise linear functions with finitely many pieces. It is…

Metric Geometry · Mathematics 2026-01-21 J. Elisenda Grigsby , Kathryn Lindsey , Robert Meyerhoff , Chenxi Wu
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