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Data is evolving with the rapid progress of population and communication for various types of devices such as networks, cloud computing, Internet of Things (IoT), actuators, and sensors. The increment of data and communication content goes…

Machine Learning · Computer Science 2021-02-05 Swarajya Lakshmi V Papineni , Snigdha Yarlagadda , Harita Akkineni , A. Mallikarjuna Reddy

One of the most popular tools for large scale gene expression studies are high-density oligonucleotide (GeneChip(R)) arrays. These currently have 16-20 small probe cells (``features'') for evaluating the transcript abundance of each gene.…

Biological Physics · Physics 2007-05-23 Felix Naef , Daniel A. Lim , Nila Patil , Marcelo O. Magnasco

DNA microarray technology enables the simultaneous measurement of expression levels of thousands of genes, thereby facilitating the understanding of the molecular mechanisms underlying complex diseases such as brain tumors and the…

Machine Learning · Computer Science 2025-08-29 Emine Akpinar , Batuhan Hangun , Murat Oduncuoglu , Oguz Altun , Onder Eyecioglu , Zeynel Yalcin

In modern dynamic constantly developing society, more and more people suffer from chronic and serious diseases and doctors and patients need special and sophisticated medical and health support. Accordingly, prominent health stakeholders…

Computers and Society · Computer Science 2022-08-10 Mirjana Ivanovic , Serge Autexier , Miltiadis Kokkonidis

This systematic review focuses on analyzing the use of machine learning techniques for identifying and quantifying analytes in various electrochemical applications, presenting the available applications in the literature. Machine learning…

In contemporary age, Computational Intelligence (CI) performs an essential role in the interpretation of big biological data considering that it could provide all of the molecular biology and DNA sequencing computations. For this purpose,…

Other Computer Science · Computer Science 2020-10-02 Zainab Alansari , Nor Badrul Anuar , Amirrudin Kamsin , Safeeullah Soomro , Mohammad Riyaz Belgaum

Artificial Intelligence (AI) provides many opportunities to improve private and public life. Discovering patterns and structures in large troves of data in an automated manner is a core component of data science, and currently drives…

Artificial Intelligence · Computer Science 2019-10-11 Vaishak Belle

The accurate quantification of gene expression levels is crucial for transcriptome study. Microarray platforms are commonly used for simultaneously interrogating thousands of genes in the past decade, and recently RNA-Seq has emerged as a…

Applications · Statistics 2014-08-01 Zhaonan Sun , Thomas Kuczek , Yu Zhu

Detecting the interactions of genetic compounds like genes, SNPs, proteins, metabolites, etc. can potentially unravel the mechanisms behind complex traits and common genetic disorders. Several methods have been taken into consideration for…

Computational Engineering, Finance, and Science · Computer Science 2015-05-26 Francesco Gadaleta

Artificial intelligence (AI) solutions that automatically extract information from digital histology images have shown great promise for improving pathological diagnosis. Prior to routine use, it is important to evaluate their predictive…

Microarray techniques are widely used in Gene expression analysis. These techniques are based on discovering submatrices of genes that share similar expression patterns across a set of experimental conditions with coherence constraint.…

Quantitative Methods · Quantitative Biology 2020-01-27 Bilal Taher , Muhammad. H Fares , Saeed Jalili

Inference of gene regulatory networks has been an active area of research for around 20 years, leading to the development of sophisticated inference algorithms based on a variety of assumptions and approaches. With the always increasing…

Molecular Networks · Quantitative Biology 2022-11-03 Malvina Marku , Vera Pancaldi

Discovering causal genetic variants from large genetic association studies poses many difficult challenges. Assessing which genetic markers are involved in determining trait status is a computationally demanding task, especially in the…

Genomics · Quantitative Biology 2015-04-09 Andrew L. Beam , Alison Motsinger-Reif , Jon Doyle

Alongside the growth of generative AI, we are witnessing a surge in the use of synthetic data across all stages of the AI development pipeline. It is now common practice for researchers and practitioners to use one large generative model…

Human-Computer Interaction · Computer Science 2025-05-14 Shivani Kapania , Stephanie Ballard , Alex Kessler , Jennifer Wortman Vaughan

CRISPR-based genome editing has revolutionized biotechnology, yet optimizing guide RNA (gRNA) design for efficiency and safety remains a critical challenge. Recent advances (2020--2025, updated to reflect current year if needed) demonstrate…

Quantitative Methods · Quantitative Biology 2025-08-29 Alireza Abbaszadeh , Armita Shahlai

The overall aim of the software industry is to ensure delivery of high quality software to the end user. To ensure high quality software, it is required to test software. Testing ensures that software meets user specifications and…

Software Engineering · Computer Science 2014-11-06 Chayanika Sharma , Sangeeta Sabharwal , Ritu Sibal

Minimally invasive image guided treatment procedures often employ advanced image processing algorithms. The recent developments of artificial intelligence algorithms harbor potential to further enhance this domain. In this article we…

Computer Vision and Pattern Recognition · Computer Science 2021-06-30 Daniel Ruijters

The effort to identify genes with periodic expression during the cell cycle from genome-wide microarray time series data has been ongoing for a decade. However, the lack of rigorous modeling of periodic expression as well as the lack of a…

Applications · Statistics 2010-11-10 Xiaodan Fan , Saumyadipta Pyne , Jun S. Liu

We propose a modification of linear discriminant analysis, referred to as compressive regularized discriminant analysis (CRDA), for analysis of high-dimensional datasets. CRDA is specially designed for feature elimination purpose and can be…

Methodology · Statistics 2018-04-12 Muhammad Naveed Tabassum , Esa Ollila

In the rapidly evolving field of artificial intelligence, the creation and utilization of synthetic datasets have become increasingly significant. This report delves into the multifaceted aspects of synthetic data, particularly emphasizing…

Machine Learning · Computer Science 2024-01-04 Shuang Hao , Wenfeng Han , Tao Jiang , Yiping Li , Haonan Wu , Chunlin Zhong , Zhangjun Zhou , He Tang
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