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We study a diffuse interface model describing the motion of two viscous fluids driven by the surface tension in a Hele-Shaw cell. The full system consists of the Cahn-Hilliard equation coupled with the Darcy's law. We address the physically…

Analysis of PDEs · Mathematics 2019-03-12 Andrea Giorgini

In this paper we study a cross-diffusion system whose coefficient matrix is non-symmetric and degenerate. The system arises in the study of tissue growth with autophagy. The existence of a weak solution is established. We also investigate…

Analysis of PDEs · Mathematics 2021-06-22 Jian-Guo Liu , Xiangsheng Xu

Understanding the untreated tumor growth kinetics and its intrinsic findings is interesting and intriguing. The aim of this study is to propose an approximate analytical expression that allows to simulate changes in surface charge density…

In this paper, we conduct a thorough mathematical analysis of a tumor growth model with treatments. The model is a system describing the evolution of metastatic tumors and the number of cells present in a primary tumor. The former evolution…

Analysis of PDEs · Mathematics 2022-05-25 Slah Eddin Ben Abdeljalil , Atef Ben Essid , Saloua Mani Aouadi

The porous medium type reaction-diffusion equation and the Hele-Shaw problem are two free boundary problems linked through the incompressible (Hele-Shaw) limit. We investigate and compare the sharp power concavities of the pressures on…

Analysis of PDEs · Mathematics 2025-09-11 Qingyou He

This paper aims at proving asymptotic stability of the radial stationary solution of a free boundary problem modeling the growth of nonnecrotic tumors with fluid-like tissues. In a previous paper we considered the case where the nutrient…

Analysis of PDEs · Mathematics 2008-06-10 Junde Wu , Shangbin Cui

We consider viscosity solution to one-phase free boundary problems for general fully nonlinear operators and free boundary condition depending on the normal vector. We show existence of viscosity solutions via the Perron's method and we…

Analysis of PDEs · Mathematics 2025-01-22 Matteo Carducci , Bozhidar Velichkov

We study a free boundary problem modeling multi-layer tumor growth with a small time delay $\tau$, representing the time needed for the cell to complete the replication process. The model consists of two elliptic equations which describe…

Analysis of PDEs · Mathematics 2022-06-22 Wenhua He , Ruixiang Xing , Bei Hu

We consider a biphasic continuum model for avascular tumour growth in two spatial dimensions, in which a cell phase and a fluid phase follow conservation of mass and momentum. A limiting nutrient that follows a diffusion process controls…

Numerical Analysis · Mathematics 2020-10-21 Jerome Droniou , Jennifer A. Flegg , Gopikrishnan C. Remesan

In this paper we study asymptotic behavior of solutions for a multidimensional free boundary problem modelling the growth of nonnecrotic tumors. We first establish a general result for differential equations in Banach spaces possessing a…

Analysis of PDEs · Mathematics 2007-12-18 Shangbin Cui

Many physical systems of interest involve the close interaction of a flow in a domain with complex, time-varying boundaries. Treatment of boundaries of this nature is cumbersome due to the difficulty in explicitly tracking boundaries that…

Fluid Dynamics · Physics 2025-02-25 Emma M. Boyd , Eric Sandall , Maycon Meier , J. Matt Quinlan , Brandon Runnels

The aim of this paper is to investigate the asymptotic behavior of a biphase tumor fluid flow derived by 2-scale homogenisation techniques in recent works. This biphase fluid flow model accounts for the capillary wall permeability, and the…

Analysis of PDEs · Mathematics 2021-01-12 Cristina Vaghi , Sébastien Benzekry , Clair Poignard

We study the displacement of three immiscible Stokes fluids with constant viscosities in a porous medium. The middle-layer fluid is contained in a bounded region. We give an analysis of the linear stability of this process. This stability…

Analysis of PDEs · Mathematics 2022-03-22 Gelu I. Pasa

We study a moving boundary problem modeling an injected fluid into another viscous fluid. The viscous fluid is withdrawn at infinity and governed by Darcy's law. We present solutions to the free boundary problem in terms of time-derivative…

Analysis of PDEs · Mathematics 2010-10-13 Lavi Karp

We propose a numerical method to approximate viscosity solutions of fully nonlinear free transmission problems. The method discretises a two-layer regularisation of a PDE, involving a functional and a vanishing parameter. The former is…

Numerical Analysis · Mathematics 2025-09-18 Edgard A. Pimentel , Ercília Sousa

We derive various novel free boundary problems as limits of a coupled bulk-surface reaction-diffusion system modelling ligand-receptor dynamics on evolving domains. These limiting free boundary problems may be formulated as Stefan-type…

Analysis of PDEs · Mathematics 2024-07-24 Amal Alphonse , Diogo Caetano , Charles M. Elliott , Chandrasekhar Venkataraman

In this paper we study a linearized eigenvalue problem derived from a a free boundary problem modeling the growth of a tumor containing two species of cells: proliferating cells and quiescent cells. The reduced form of this eigenvalue…

Analysis of PDEs · Mathematics 2018-10-19 Shangbin Cui , Jiayue Zheng

We study a model introduced by Perthame and Vauchelet that describes the growth of a tumor governed by Brinkman's Law, which takes into account friction between the tumor cells. We adopt the viscosity solution approach to establish an…

Analysis of PDEs · Mathematics 2017-04-24 Inwon Kim , Olga Turanova

We consider the process of convective dissolution in homogeneous and isotropic porous media. The flow is unstable due to the presence of a solute that induces a density difference responsible for driving the flow. The mixing dynamics is…

Fluid Dynamics · Physics 2024-08-02 Marco De Paoli , Christopher J. Howland , Roberto Verzicco , Detlef Lohse

We study a tumor growth model in two space dimensions, where proliferation of the tumor cells leads to expansion of the tumor domain and migration of surrounding normal tissues into the exterior vacuum. The model features two moving…

Analysis of PDEs · Mathematics 2020-02-11 Inwon Kim , Jiajun Tong
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