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Identifying complex neural circuitry from electron microscopic (EM) images may help unlock the mysteries of the brain. However, identifying this circuitry requires time-consuming, manual tracing (proofreading) due to the size and intricacy…

Quantitative Methods · Quantitative Biology 2014-09-04 Stephen M. Plaza

Gliomas are the most common malignant brain tumors that are treated with chemoradiotherapy and surgery. Magnetic Resonance Imaging (MRI) is used by radiotherapists to manually segment brain lesions and to observe their development…

Image and Video Processing · Electrical Eng. & Systems 2020-11-30 Jonas Wacker , Marcelo Ladeira , José Eduardo Vaz Nascimento

In this paper we propose a deep learning approach for segmenting sub-cortical structures of the human brain in Magnetic Resonance (MR) image data. We draw inspiration from a state-of-the-art Fully-Convolutional Neural Network (F-CNN)…

Computer Vision and Pattern Recognition · Computer Science 2016-02-08 Mahsa Shakeri , Stavros Tsogkas , Enzo Ferrante , Sarah Lippe , Samuel Kadoury , Nikos Paragios , Iasonas Kokkinos

The tracing of neural pathways through large volumes of image data is an incredibly tedious and time-consuming process that significantly encumbers progress in neuroscience. We are exploring deep learning's potential to automate…

Computer Vision and Pattern Recognition · Computer Science 2018-09-05 Ishtar Nyawira , Kristi Bushman , Iris Qian , Annie Zhang

Reconstructing a map of neuronal connectivity is a critical challenge in contemporary neuroscience. Recent advances in high-throughput serial section electron microscopy (EM) have produced massive 3D image volumes of nanoscale brain tissue…

We present a novel approach to automatically segment magnetic resonance (MR) images of the human brain into anatomical regions. Our methodology is based on a deep artificial neural network that assigns each voxel in an MR image of the brain…

Computer Vision and Pattern Recognition · Computer Science 2015-06-26 Alexandre de Brebisson , Giovanni Montana

The computational imaging technique of Fourier Ptychographic Microscopy (FPM) enables high-resolution imaging with a wide field of view and can serve as an extremely valuable tool, e.g. in the classification of cells in medical…

Image and Video Processing · Electrical Eng. & Systems 2025-08-25 Navya Sonal Agarwal , Jan Philipp Schneider , Kanchana Vaishnavi Gandikota , Syed Muhammad Kazim , John Meshreki , Ivo Ihrke , Michael Moeller

In this paper, we propose an automatic brain tumor segmentation approach (e.g., PixelNet) using a pixel-level convolutional neural network (CNN). The model extracts feature from multiple convolutional layers and concatenate them to form a…

Image and Video Processing · Electrical Eng. & Systems 2022-04-26 Mobarakol Islam , Hongliang Ren

Downsampling images and labels, often necessitated by limited resources or to expedite network training, leads to the loss of small objects and thin boundaries. This undermines the segmentation network's capacity to interpret images…

Image and Video Processing · Electrical Eng. & Systems 2024-10-27 Shahzad Ali , Yu Rim Lee , Soo Young Park , Won Young Tak , Soon Ki Jung

Convolutional neural networks (CNNs) have shown promising results on several segmentation tasks in magnetic resonance (MR) images. However, the accuracy of CNNs may degrade severely when segmenting images acquired with different scanners…

Machine Learning · Statistics 2018-05-28 Neerav Karani , Krishna Chaitanya , Christian Baumgartner , Ender Konukoglu

Ensembles of networks arise in various fields where multiple independent networks are observed on the same set of nodes, for example, a collection of brain networks constructed on the same brain regions for different individuals. However,…

Methodology · Statistics 2022-01-21 Sa Ren , Xue Wang , Peng Liu , Jian Zhang

Recent advances in imaging and high-performance computing have made it possible to image the entire human brain at the cellular level. This is the basis to study the multi-scale architecture of the brain regarding its subdivision into brain…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Jan-Oliver Kropp , Christian Schiffer , Katrin Amunts , Timo Dickscheid

Fueled by recent advances in machine learning, there has been tremendous progress in the field of semantic segmentation for the medical image computing community. However, developed algorithms are often optimized and validated by hand based…

Image and Video Processing · Electrical Eng. & Systems 2020-05-21 Oliver Rippel , Leon Weninger , Dorit Merhof

The automated analysis of microscopy images is a challenge in the context of single-cell tracking and quantification. This work has as goals the study of the performance of deep learning for segmenting microscopy images and the improvement…

Quantitative Methods · Quantitative Biology 2022-10-05 André O. Françani

With the development of Deep Neural Networks (DNNs), many efforts have been made to handle medical image segmentation. Traditional methods such as nnUNet train specific segmentation models on the individual datasets. Plenty of recent…

Computer Vision and Pattern Recognition · Computer Science 2024-07-12 Xiaobao Wei , Jiajun Cao , Yizhu Jin , Ming Lu , Guangyu Wang , Shanghang Zhang

Convolutional Neural Networks (CNNs) have been recently employed to solve problems from both the computer vision and medical image analysis fields. Despite their popularity, most approaches are only able to process 2D images while most…

Computer Vision and Pattern Recognition · Computer Science 2016-06-16 Fausto Milletari , Nassir Navab , Seyed-Ahmad Ahmadi

Convolutional neural networks (CNNs) have been applied to various automatic image segmentation tasks in medical image analysis, including brain MRI segmentation. Generative adversarial networks have recently gained popularity because of…

Computer Vision and Pattern Recognition · Computer Science 2017-07-12 Pim Moeskops , Mitko Veta , Maxime W. Lafarge , Koen A. J. Eppenhof , Josien P. W. Pluim

Precise segmentation and anatomical identification of the vertebrae provides the basis for automatic analysis of the spine, such as detection of vertebral compression fractures or other abnormalities. Most dedicated spine CT and MR scans as…

Computer Vision and Pattern Recognition · Computer Science 2019-02-15 Nikolas Lessmann , Bram van Ginneken , Pim A. de Jong , Ivana Išgum

This article suggests an algorithm of formation a training set for artificial neural network in case of image segmentation. The distinctive feature of this algorithm is that it using only one image for segmentation. The segmentation…

Computer Vision and Pattern Recognition · Computer Science 2018-12-27 S. V. Belim , S. B. Larionov

This paper addresses the task of nuclei segmentation in high-resolution histopathological images. We propose an auto- matic end-to-end deep neural network algorithm for segmenta- tion of individual nuclei. A nucleus-boundary model is…

Computer Vision and Pattern Recognition · Computer Science 2020-03-18 Yuxin Cui , Guiying Zhang , Zhonghao Liu , Zheng Xiong , Jianjun Hu