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We present a technically simple implementation of quantitative phase imaging in confocal microscopy based on synthetic optical holography with sinusoidal-phase reference waves. Using a Mirau interference objective and low-amplitude vertical…

The correlation properties of light provide an outstanding tool to overcome the limitations of traditional imaging techniques. A relevant case is represented by correlation plenoptic imaging (CPI), a quantum-inspired volumetric imaging…

Advancements in high-throughput biomedical applications require real-time, large field-of-view (FOV) imaging. While current 2D lens-free imaging (LFI) systems improve FOV, they are often hindered by time-consuming multi-position…

An integrated microscope that combines different optical techniques for simultaneous imaging is demonstrated. The microscope enables spectral-domain optical coherence microscopy based on optical backscatter, and multi-photon microscopy for…

Optics · Physics 2009-11-11 C. Vinegoni , T. Ralston , W. Tan , W. Luo , D. L. Marks , S. A. Boppart

Operando microscopy provides direct insight into the dynamic chemical and physical processes that govern functional materials, yet measurement noise limits the effective resolution and undermines quantitative analysis. Here, we present a…

Computer Vision and Pattern Recognition · Computer Science 2025-11-03 Samuel Degnan-Morgenstern , Alexander E. Cohen , Rajeev Gopal , Megan Gober , George J. Nelson , Peng Bai , Martin Z. Bazant

The resolution of optical imaging devices is ultimately limited by the diffraction of light. To circumvent this limit, modern super-resolution microscopy techniques employ active interaction with the object by exploiting its optical…

Optics · Physics 2022-01-05 A. A. Pushkina , G. Maltese , J. I. Costa-Filho , P. Patel , A. I. Lvovsky

We present a plenoptic microscopy configuration for 3D snapshot imaging, which is dual telecentric and can directly record true projection images corresponding with different viewing angles. It also allows blocking high-angle stray rays…

Optics · Physics 2020-05-27 Yongjin Sung

Complex field imaging, which captures both the amplitude and phase information of input optical fields or objects, can offer rich structural insights into samples, such as their absorption and refractive index distributions. However,…

Optics · Physics 2024-05-30 Jingxi Li , Yuhang Li , Tianyi Gan , Che-Yung Shen , Mona Jarrahi , Aydogan Ozcan

We introduce a framework for the reconstruction of the amplitude, phase and polarisation of an optical vector-field using calibration measurements acquired by an imaging device with an unknown linear transformation. By incorporating…

The Planck Low Frequency Instrument will recover polarization by differencing the outputs from radiometers sensitive to orthogonal polarizations. We contrast the systematic errors that afflict such a system with those that affect…

Astrophysics · Physics 2014-10-13 J. P. Leahy , V. Yurchenko , Morag Hastie , M. Bersanelli , N. Mandolesi

Quantitative phase imaging (QPI) through multi-core fibers (MCFs) has been an emerging in vivo label-free endoscopic imaging modality with minimal invasiveness. However, the computational demands of conventional iterative phase retrieval…

Super-resolution fluorescence microscopy is an important tool in biomedical research for its ability to discern features smaller than the diffraction limit. However, due to its difficult implementation and high cost, the universal…

The most pressing problems in modern astrophysics have often required the largest telescopes. With the cost scaling of mirror diameters, the field as a whole is faced with a challenge -- how to replicate or improve on the collecting area…

Instrumentation and Methods for Astrophysics · Physics 2025-09-03 Megan Delamer , Suvrath Mahadevan , Chad Bender , Ceiwynn Longworth , Roger Angel , Joel Berkson , On To Sonja Choi , Kathleen Gehoski , Andy Monson , Chrisitan Schwab

Image restoration of biological structures in microscopy poses unique challenges for preserving fine textures and sharp edges. While recent GAN-based image restoration formulations have introduced frequency-domain losses for natural images,…

Quantitative Methods · Quantitative Biology 2026-01-30 Xingjian Zhang , Claire Leclech , Louison Blivet-Bailly , Abdul I. Barakat , Elsa D. Angelini

In this letter, we demonstrate the experimental mapping of the longitudinal magnetic and electric optical fields with a standard scanning microscope that involves a high numerical aperture far-field objective. The imaging concept relies…

Optics · Physics 2015-06-17 C. Ecoffey , T. Grosjean

In coherent X-ray diffraction microscopy the diffraction pattern generated by a sample illuminated with coherent x-rays is recorded, and a computer algorithm recovers the unmeasured phases to synthesize an image. By avoiding the use of a…

Selective plane illumination microscopy (SPIM), also known as light sheet fluorescence microscopy, provides high specificity through fluorescence labeling. However, it lacks complementary structural information from the surrounding context,…

Optics · Physics 2024-12-19 Rui Ma , Olga Lyraki , Daniel Wehner , Jochen Guck

Usually, off-axis digital holographic microscopy requires a coherent light source in order to record a full-field hologram. Nevertheless, a LASER-based illumination leads to a non-negligible coherent noise, decreasing then the imaging…

Optics · Physics 2021-11-02 Stephane Perrin , Jonas Kuhn , Christian Depeursinge

Laser writing of materials is normally performed by the sequential scanning of a single focused beam across a sample. This process is time-consuming and it can severely limit the throughput of laser systems in key applications such as…

Applied Physics · Physics 2019-07-22 A. Zunino , S. Surdo , M. Duocastella

Fourier light-field microscopy (FLFM) uses a micro-lens array (MLA) to segment the Fourier Plane of the microscopic objective lens to generate multiple two-dimensional perspective views, thereby reconstructing the three-dimensional(3D)…

Optics · Physics 2022-08-29 Haixin Huang , Haoyuan Qiu , Hanzhe Wu , Yihong Ji , Heng Li , Bin Yu , Danni Chen , Junle Qu
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