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Proteins are sequences of amino acids that serve as the basic building blocks of living organisms. Despite rapidly growing databases documenting structural and functional information for various protein sequences, our understanding of…

Biomolecules · Quantitative Biology 2025-01-06 Weihang Dai

With the explosive growth of big data, workloads tend to get more complex and computationally demanding. Such applications are processed on distributed interconnected resources that are becoming larger in scale and computational capacity.…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-30 Georgios L. Stavrinides , Helen D. Karatza

With rapid growth in the amount of unstructured data produced by memory-intensive applications, large scale data analytics has recently attracted increasing interest. Processing, managing and analyzing this huge amount of data poses several…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-08-29 Farshid Farhat , Diman Zad Tootaghaj , Mohammad Arjomand

The demand for artificial intelligence has grown significantly over the last decade and this growth has been fueled by advances in machine learning techniques and the ability to leverage hardware acceleration. However, in order to increase…

Machine Learning · Computer Science 2022-11-28 Joost Verbraeken , Matthijs Wolting , Jonathan Katzy , Jeroen Kloppenburg , Tim Verbelen , Jan S. Rellermeyer

Novel technologies in genomics allow creating data in exascale dimension with relatively minor effort of human and laboratory and thus monetary resources compared to capabilities only a decade ago. While the availability of this data…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-11-10 Sandra Gesing , Thomas Richard Connor , Ian Taylor

Advances in information technology and its widespread growth in several areas of business, engineering, medical and scientific studies are resulting in information/data explosion. Knowledge discovery and decision making from such rapidly…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-09-07 Raghavendra Kune , Pramodkumar Konugurthi , Arun Agarwal , Raghavendra Rao Chillarige , Rajkumar Buyya

Emerging Big Data analytics and machine learning applications require a significant amount of computational power. While there exists a plethora of large-scale data processing frameworks which thrive in handling the various complexities of…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-06-26 Jan S. Rellermeyer , Sobhan Omranian Khorasani , Dan Graur , Apourva Parthasarathy

Since the advent of next-generation sequencing in the early 2000s, the volume of bioinformatics software tools and databases has exploded and continues to grow rapidly. Documenting this evolution on a global and time-dependent scale is a…

Machine learning can provide deep insights into data, allowing machines to make high-quality predictions and having been widely used in real-world applications, such as text mining, visual classification, and recommender systems. However,…

Machine Learning · Computer Science 2020-08-11 Meng Wang , Weijie Fu , Xiangnan He , Shijie Hao , Xindong Wu

Explosive growth in data and availability of cheap computing resources have sparked increasing interest in Big learning, an emerging subfield that studies scalable machine learning algorithms, systems, and applications with Big Data.…

Machine Learning · Computer Science 2017-03-02 Jun Zhu , Jianfei Chen , Wenbo Hu , Bo Zhang

Big Data bring new opportunities to modern society and challenges to data scientists. On one hand, Big Data hold great promises for discovering subtle population patterns and heterogeneities that are not possible with small-scale data. On…

Machine Learning · Statistics 2014-12-16 Jianqing Fan , Fang Han , Han Liu

Generative artificial intelligence (GenAI) has become a transformative approach in bioinformatics that often enables advancements in genomics, proteomics, transcriptomics, structural biology, and drug discovery. To systematically identify…

In the modern world, technology is at its peak. Different avenues in programming and technology have been explored for data analysis, automation, and robotics. Machine learning is key to optimize data analysis, make accurate predictions,…

Subcellular Processes · Quantitative Biology 2023-10-18 Akshay Bhalla , Suraj Rajendran

Big data systems address the challenges of capturing, storing, managing, analyzing, and visualizing big data. Within this context, developing benchmarks to evaluate and compare big data systems has become an active topic for both research…

Performance · Computer Science 2014-02-24 Rui Han , Xiaoyi Lu

With the rapid advancements in large language model (LLM) technology and the emergence of bioinformatics-specific language models (BioLMs), there is a growing need for a comprehensive analysis of the current landscape, computational…

In contemporary age, Computational Intelligence (CI) performs an essential role in the interpretation of big biological data considering that it could provide all of the molecular biology and DNA sequencing computations. For this purpose,…

Other Computer Science · Computer Science 2020-10-02 Zainab Alansari , Nor Badrul Anuar , Amirrudin Kamsin , Safeeullah Soomro , Mohammad Riyaz Belgaum

Large systems biology projects can encompass several workgroups often located in different countries. An overview about existing data standards in systems biology and the management, storage, exchange and integration of the generated data…

Databases · Computer Science 2009-12-15 Gerhard Mayer

Many applications from various disciplines are now required to analyze fast evolving big data in real time. Various approaches for incremental processing of queries have been proposed over the years. Traditional approaches rely on updating…

Databases · Computer Science 2019-02-05 Iman Elghandour , Ahmet Kara , Dan Olteanu , Stijn Vansummeren

Big Data processing systems handle huge unstructured and structured data to store, process, and analyze through cluster analysis which helps in identifying unseen patterns to find the relationships between them. Clustering analysis over the…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-11-11 Dipesh Gyawali

Massively parallel sequencing techniques have revolutionized biological and medical sciences by providing unprecedented insight into the genomes of humans, animals, and microbes. Modern sequencing platforms generate enormous amounts of…