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The ability to collect and analyze large amounts of data is a growing problem within the scientific community. The growing gap between data and users calls for innovative tools that address the challenges faced by big data volume, velocity…

Databases · Computer Science 2016-08-01 Vijay Gadepally , Jeremy Kepner

Machine learning is a modern approach to problem-solving and task automation. In particular, machine learning is concerned with the development and applications of algorithms that can recognize patterns in data and use them for predictive…

The search for meaningful structure in biological data has relied on cutting-edge advances in computational technology and data science methods. However, challenges arise as we push the limits of scale and complexity in biological problems.…

Delivering effective data analytics is of crucial importance to the interpretation of the multitude of biological datasets currently generated by an ever increasing number of high throughput techniques. Logic programming has much to offer…

Logic in Computer Science · Computer Science 2019-09-19 Nicos Angelopoulos , Jan Wielemaker

Big data production in industrial Internet of Things (IIoT) is evident due to the massive deployment of sensors and Internet of Things (IoT) devices. However, big data processing is challenging due to limited computational, networking and…

Computers and Society · Computer Science 2019-04-12 Muhammad Habib ur Rehman , Ibrar Yaqoob , Khaled Salah , Muhammad Imran , Prem Prakash Jayaraman , Charith Perera

Big Data is reforming many industrial domains by providing decision support through analyzing large data volumes. Big Data testing aims to ensure that Big Data systems run smoothly and error-free while maintaining the performance and…

Artificial Intelligence · Computer Science 2022-07-15 Iram Arshad , Saeed Hamood Alsamhi , Wasif Afzal

Advancements in artificial intelligence, machine learning, and deep learning have catalyzed the transformation of big data analytics and management into pivotal domains for research and application. This work explores the theoretical…

Inclusion of high throughput technologies in the field of biology has generated massive amounts of biological data in the recent years. Now, transforming these huge volumes of data into knowledge is the primary challenge in computational…

Machine Learning · Computer Science 2021-12-06 Dibyendu Ghosh , Srija Chakraborty , Hariprasad Kodamana , Supriya Chakraborty

Current metagenomic analysis algorithms require significant computing resources, can report excessive false positives (type I errors), may miss organisms (type II errors / false negatives), or scale poorly on large datasets. This paper…

Databases · Computer Science 2015-01-23 Ashley Mae Conard , Stephanie Dodson , Jeremy Kepner , Darrell Ricke

Advances in molecular technologies underlie an enormous growth in the size of data sets pertaining to biology and biomedicine. These advances parallel those in the deep learning subfield of machine learning. Components in the differentiable…

Quantitative Methods · Quantitative Biology 2024-06-14 Alex Jihun Lee , Reza Abbasi-Asl

Recent technological advancements in data acquisition tools allowed life scientists to acquire multimodal data from different biological application domains. Broadly categorized in three types (i.e., sequences, images, and signals), these…

Quantitative Methods · Quantitative Biology 2020-03-03 Mufti Mahmud , M Shamim Kaiser , Amir Hussain

Deep learning is an advanced technology that relies on large-scale data and complex models for feature extraction and pattern recognition. It has been widely applied across various fields, including computer vision, natural language…

Genomics · Quantitative Biology 2024-12-24 Yindan Luo , Jiaxin Cai

While deep learning excels in natural image and language processing, its application to high-dimensional data faces computational challenges due to the dimensionality curse. Current large-scale data tools focus on business-oriented…

Machine Learning · Computer Science 2025-07-01 Chen Zhang

Federated learning leverages data across institutions to improve clinical discovery while complying with data-sharing restrictions and protecting patient privacy. This paper provides a gentle introduction to this approach in bioinformatics,…

The emergence of cloud computing has made dynamic provisioning of elastic capacity to applications on-demand. Cloud data centers contain thousands of physical servers hosting orders of magnitude more virtual machines that can be allocated…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-11-17 Rajkumar Buyya , Kotagiri Ramamohanarao , Chris Leckie , Rodrigo N. Calheiros , Amir Vahid Dastjerdi , Steve Versteeg

One of the most significant problems of Big Data is to extract knowledge through the huge amount of data. The usefulness of the extracted information depends strongly on data quality. In addition to the importance, data quality has recently…

Databases · Computer Science 2020-05-25 Mostafa Mirzaie , Behshid Behkamal , Samad Paydar

Large Language Models (LLMs) are revolutionizing bioinformatics, enabling advanced analysis of DNA, RNA, proteins, and single-cell data. This survey provides a systematic review of recent advancements, focusing on genomic sequence modeling,…

Computation and Language · Computer Science 2026-03-03 Zhenyu Wang , Zikang Wang , Jiyue Jiang , Pengan Chen , Xiangyu Shi , Yu Li

Curating, processing, and combining large-scale medical imaging datasets from national studies is a non-trivial task due to the intense computation and data throughput required, variability of acquired data, and associated financial…

Bi-clustering is a useful approach in analyzing biological data when observations come from heterogeneous groups and have a large number of features. We outline a general Bayesian approach in tackling bi-clustering problems in moderate to…

Applications · Statistics 2021-02-11 Han Yan , Jiexing Wu , Yang Li , Jun S. Liu

The area of online machine learning in big data streams covers algorithms that are (1) distributed and (2) work from data streams with only a limited possibility to store past data. The first requirement mostly concerns software…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-02-19 András A. Benczúr , Levente Kocsis , Róbert Pálovics