Related papers: Design and Microfabrication Considerations for Rel…
This study introduces a novel, flexible, and implantable neural probe using a cost-effective microfabrication process based on a thin polyimide film. Polyimide film, known as Kapton, serves as a flexible substrate for microelectrodes,…
Current techniques of neuroimaging, including electrical devices, are either of low spatiotemporal resolution or invasive, impeding multiscale monitoring of brain activity at both single cell and network levels. Overcoming this issue is of…
Neural prosthetics are typically situated in an aggressive, biochemical environment that requires materials with superior stability and performance. These probes have dual functionalities of recording and stimulation. The material stability…
Drug resistant focal epilepsy can be treated by resecting the epileptic focus requiring a precise focus localization using stereoelectroencephalography (SEEG) probes. As commercial SEEG probes offer only a limited spatial resolution, probes…
Daily monitoring of internal tissues with conformable and breathable ultrasound (US) imaging probes is promising for early detection of diseases. In recent years, textile substrates are widely used for wearable devices since they satisfy…
Targeted light delivery into biological tissue is needed in applications such as optogenetic stimulation of the brain and in vivo functional or structural imaging of tissue. These applications require very compact, soft, and flexible…
Establishing a reliable communication interface between the brain and electronic devices is of paramount importance for exploiting the full potential of neural prostheses. Current microelectrode technologies for recording electrical…
In this paper, the resistive switching and neuromorphic behavior of memristive devices based on parylene, a polymer both low-cost and safe for the human body, is comprehensively studied. The Metal/Parylene/ITO sandwich structures were…
Advances in chip-scale photonic-electronic integration are enabling a new generation of foundry-manufacturable implantable silicon neural probes incorporating nanophotonic waveguides and microelectrodes for optogenetic stimulation and…
In this work, we investigate the impact of Fabry-Perot (FP) cavities formed between a fiber array and a silicon chip during edge-coupled testing of photonic integrated circuits (PICs). Our results show that subwavelength variations in the…
Although microarrays are routine analysis tools in biomedical research, they still yield noisy output that often requires experimental confirmation. Many studies have aimed at optimizing probe design and statistical analysis to tackle this…
Extracellular, large scale in vivo recording of neural activity is mandatory for elucidating the interaction of neurons within large neural networks at the level of their single unit activity. Technological achievements in MEMS-based…
In the intact brain, neural activity can be recorded using sensing electrodes and manipulated using light stimulation. Silicon probes with integrated electrodes and micro-LEDs enable the detection and control of neural activity using a…
Recent advances in quantum information processing with trapped ions have demonstrated the need for new ion trap architectures capable of holding and manipulating chains of many (>10) ions. Here we present the design and detailed…
Nanophotonics provides the ability to rapidly and precisely reconfigure light beams on a compact platform. Infrared nanophotonic devices are widely used in data communications to overcome traditional bandwidth limitations of electrical…
Recent advances in material technology and in micro- and nano-electronics have profoundly changed the design of intracranial electrophysiology electrodes. It is now possible to manufacture electrodes that record cortical activity at a…
Robotically steerable compliant surgical tools offer several advantages over rigid tools, including enhanced dexterity, reduced tissue damage, and the ability to generate non-linear trajectories in minimally invasive neurosurgical…
The wearable EEG device sector is advancing rapidly, enabling fast and reliable detection of brain activity for investigating brain function and pathology. However, many current EEG systems remain challenging for users with neurological…
There are many fields where it is of interest to measure the elastic moduli of tiny fragile fibers, such as filamentous bacteria, actin filaments, DNA, carbon nanotubes, and functional microfibers. The elastic modulus is typically deduced…
Graphene solution-gated field-effect transistors (SGFETs) are a promising platform for the recording of cell action potentials due to the intrinsic high signal amplification of graphene transistors. In addition, graphene technology fulfils…