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We show that a cumulative action of noise and delayed feedback on an excitable theta-neuron leads to rather coherent stochastic bursting. An idealized point process, valid if the characteristic time scales in the problem are well-separated,…

Statistical Mechanics · Physics 2018-11-07 Chunming Zheng , Arkady Pikovsky

The influence that intrinsic local density fluctuations can have on solutions of mean-field reaction-diffusion models is investigated numerically by means of the spatial patterns arising from two species that react and diffuse in the…

Other Condensed Matter · Physics 2007-05-23 D. Hochberg , M. -P. Zorzano , F. Moran

We analyze the spatio-temporal patterns of two competing species in the presence of two white noise sources: an additive noise acting on the interaction parameter and a multiplicative noise which affects directly the dynamics of the species…

Statistical Mechanics · Physics 2007-05-23 D. Valenti , A. Fiasconaro , B. Spagnolo

We investigate Turing pattern formation in a stochastic reaction-diffusion model defined on $N$ lattice sites, where each lattice site is associated with a reaction vessel of volume $\Omega$. We focus on a regime where spatial discreteness…

Statistical Mechanics · Physics 2025-12-12 Yusuke Yanagisawa , Shin-ichi Sasa

Transcriptional delay can significantly impact the dynamics of gene networks. Here we examine how such delay affects bistable systems. We investigate several stochastic models of bistable gene networks and find that increasing delay…

Molecular Networks · Quantitative Biology 2015-06-16 Chinmaya Gupta , José Manuel López , William Ott , Krešimir Josíc , Matthew R. Bennett

This paper studies the effects of a time-delayed feedback control on the appearance and development of spatiotemporal patterns in a reaction-diffusion system. Different types of control schemes are investigated, including single-species,…

Chaotic Dynamics · Physics 2012-09-21 Y. N. Kyrychko , K. B. Blyuss , S. J. Hogan , E. Schoell

Timing is essential for many cellular processes, from cellular responses to external stimuli to the cell cycle and circadian clocks. Many of these processes are based on gene expression. For example, an activated gene may be required to…

Molecular Networks · Quantitative Biology 2017-02-24 Alma Dal Co , Marco Cosentino Lagomarsino , Michele Caselle , Matteo Osella

We study a stochastic model of protein dynamics that explicitly includes delay in the degradation. We rigorously derive the master equation for the processes and solve it exactly. We show that the equations for the mean values obtained…

Statistical Mechanics · Physics 2013-05-29 Luis F. Lafuerza , Raul Toral

We study the noise characteristics of stochastic oscillations in protein number dynamics of simple genetic oscillatory systems. Using the three-component negative feedback transcription regulatory system called the repressilator as a…

Molecular Networks · Quantitative Biology 2015-03-13 Byungjoon Min , K. -I. Goh , I. -M. Kim

The counterintuitive emergence of order from noise is a central phenomenon in science, ranging from pattern formation and synchronization to order-by-disorder in frustrated systems. While large-scale spatial self-organization induced by…

Soft Condensed Matter · Physics 2026-02-02 Satyam Anand , Guanming Zhang , Stefano Martiniani

Effect of a complicated many-body environment is analyzed on the chaotic motion of a quantum particle in a mesoscopic ballistic structure. The dephasing and absorption phenomena are treated on the same footing in the framework of a…

Mesoscale and Nanoscale Physics · Physics 2007-05-23 Valentin V. Sokolov

Gene expression is inherently a noisy process which manifests as cell-to-cell variability in time evolution of proteins. Consequently, events that trigger at critical threshold levels of regulatory proteins exhibit stochasticity in their…

Subcellular Processes · Quantitative Biology 2016-09-26 Khem Raj Ghusinga , Abhyudai Singh

Boundary-induced pattern formation from a spatially uniform state is investigated using one-dimensional reaction-diffusion equations. The temporal oscillation is successively transformed into a spatially periodic pattern, triggered by…

Pattern Formation and Solitons · Physics 2017-02-01 Takahiro Kohsokabe , Kunihiko Kaneko

Shortcuts in a regular architecture affect the information transport through the system due to the severe decrease in average path length. A fundamental new perspective in terms of pattern formation is the destabilizing effect of…

Statistical Mechanics · Physics 2009-11-11 Carsten Marr , Marc-Thorsten Huett

It is well known that the kinetics of an intracellular biochemical network is stochastic. This is due to intrinsic noise arising from the random timing of biochemical reactions in the network as well as due to extrinsic noise stemming from…

Subcellular Processes · Quantitative Biology 2019-06-05 Emma M. Keizer , Bjorn Bastian , Robert W. Smith , Ramon Grima , Christian Fleck

Spatial organisation is a hallmark of all living cells, and recreating it in model systems is a necessary step in the creation of synthetic cells. It is therefore of both fundamental and practical interest to better understand the basic…

Biological Physics · Physics 2017-12-19 Jaime Agudo-Canalejo , Ramin Golestanian

We demonstrate that demographic noise can induce persistent spatial pattern formation and temporal oscillations in the Levin-Segel predator-prey model for plankton-herbivore population dynamics. Although the model exhibits a Turing…

Populations and Evolution · Quantitative Biology 2015-05-13 Thomas Butler , Nigel Goldenfeld

During tissue development, patterns of gene expression determine the spatial arrangement of cell types. In many cases, gradients of secreted signaling molecules - morphogens - guide this process. The continuous positional information…

Molecular Networks · Quantitative Biology 2017-02-08 Ruben Perez-Carrasco , Pilar Guerrero , James Briscoe , Karen Page

Delays in protein synthesis cause a confounding effect when constructing Gene Regulatory Networks (GRNs) from RNA-sequencing time-series data. Accurate GRNs can be very insightful when modelling development, disease pathways, and drug…

Molecular Networks · Quantitative Biology 2020-10-07 Jacob Moss , Pietro Lió

A genetic switch may be realised by a certain operator sector on the DNA strand from which either genetic code, to the left or to the right of this operator sector, can be transcribed and the corresponding information processed. This switch…

Statistical Mechanics · Physics 2013-01-24 Ralf Metzler