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The discriminative approach to classification using deep neural networks has become the de-facto standard in various fields. Complementing recent reservations about safety against adversarial examples, we show that conventional…

Machine Learning · Computer Science 2018-07-25 William Wang , Angelina Wang , Aviv Tamar , Xi Chen , Pieter Abbeel

Understanding cell cycle dynamics is crucial for studying biological processes such as growth, development and disease progression. While fluorescent protein reporters like the Fucci system allow live monitoring of cell cycle phases, they…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Louis-Alexandre Leger , Maxine Leonardi , Andrea Salati , Felix Naef , Martin Weigert

Spatial models where growth is limited to the edge of the expansions have been instrumental to understand the population dynamics and the clone size distribution in growing cellular populations, such as microbial colonies and avascular…

Populations and Evolution · Quantitative Biology 2022-06-08 Armin Eghdami , Jayson Paulose , Diana Fusco

We introduce and study the dynamics of an \emph{immortal} critical branching process. In the classic, critical branching process, particles give birth to a single offspring or die at the same rates. Even though the average population is…

Probability · Mathematics 2021-06-22 P. L. Krapivsky , S. Redner

Majority of state-of-the-art deep learning methods are discriminative approaches, which model the conditional distribution of labels given inputs features. The success of such approaches heavily depends on high-quality labeled instances,…

Machine Learning · Computer Science 2019-09-13 Yanwu Xu , Mingming Gong , Junxiang Chen , Tongliang Liu , Kun Zhang , Kayhan Batmanghelich

Diagnosing diseases such as leukemia or anemia requires reliable counts of blood cells. Hematologists usually label and count microscopy images of blood cells manually. In many cases, however, cells in different maturity states are…

Machine Learning · Computer Science 2020-07-13 Yushan Liu , Markus M. Geipel , Christoph Tietz , Florian Buettner

Cell formation is a critical step in the design of cellular manufacturing systems. Recently, it was tackled using a cut-based-graph-partitioning model. This model meets real-life production systems requirements as it uses the actual amount…

Discrete Mathematics · Computer Science 2016-12-19 Boulif Menouar

This paper addresses the problem of making statistical inference about a population that can only be identified through classifier predictions. The problem is motivated by scientific studies in which human labels of a population are…

Applications · Statistics 2021-06-15 Ciaran Evans , Zara Y. Weinberg , Manojkumar A. Puthenveedu , Max G'Sell

The emergence of a predominant phenotype within a cell population is often triggered by a rare accumulation of DNA mutations in a single cell. For example, tumors may be initiated by a single cell in which multiple mutations cooperate to…

Tissues and Organs · Quantitative Biology 2018-11-21 Philip Greulich , Benjamin D. Simons

What is aging? Mechanistic answers to this question remain elusive despite decades of research. Here, we propose a mathematical model of cellular aging based on a model gene interaction network. Our network model is made of only non-aging…

Molecular Networks · Quantitative Biology 2023-09-12 Hong Qin

Label-free single-cell imaging offers a scalable, non-invasive alternative to fluorescence-based cytometry, yet inferring molecular phenotypes directly from bright-field morphology remains challenging. We present a unified Deep Learning…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Saqib Nazir , Ardhendu Behera

In recent years, several unsupervised cell segmentation methods have been presented, trying to omit the requirement of laborious pixel-level annotations for the training of a cell segmentation model. Most if not all of these methods handle…

Computer Vision and Pattern Recognition · Computer Science 2023-12-04 Mehdi Naouar , Gabriel Kalweit , Anusha Klett , Yannick Vogt , Paula Silvestrini , Diana Laura Infante Ramirez , Roland Mertelsmann , Joschka Boedecker , Maria Kalweit

Recent methods for conditional image generation benefit from dense supervision such as segmentation label maps to achieve high-fidelity. However, it is rarely explored to employ dense supervision for unconditional image generation. Here we…

Computer Vision and Pattern Recognition · Computer Science 2022-07-28 Gayoung Lee , Hyunsu Kim , Junho Kim , Seonghyeon Kim , Jung-Woo Ha , Yunjey Choi

A common and effective method for calculating the steady-state distribution of a process under stochastic resetting is the renewal approach that requires only the knowledge of the reset-free propagator of the underlying process and the…

Statistical Mechanics · Physics 2024-11-15 Ron Vatash , Amy Altshuler , Yael Roichman

The cellular tree classifier model addresses a fundamental problem in the design of classifiers for a parallel or distributed computing world: Given a data set, is it sufficient to apply a majority rule for classification, or shall one…

Machine Learning · Statistics 2013-06-26 Gérard Biau , Luc Devroye

This paper presents an interesting experimental example of voter-model statistics in biology. In recent work on mouse tail-skin, where proliferating cells are confined to a two-dimensional layer, we showed that cells proliferate and…

Biological Physics · Physics 2009-11-13 Allon M. Klein , David P. Doupe , Philip H. Jones , Benjamin D. Simons

Recognising and reacting to change in non-stationary data-streams is a challenging task. The majority of research in this area assumes that the true class label of incoming points are available, either at each time step or intermittently…

Neural and Evolutionary Computing · Computer Science 2023-12-27 Conor Fahy , Shengxiang Yang

In this article, we consider a generalization of Young tableaux in which we allow some consecutive pairs of cells with decreasing labels. We show that this leads to a rich variety of combinatorial formulas, which suggest that these new…

Discrete Mathematics · Computer Science 2018-05-24 Cyril Banderier , Philippe Marchal , Michael Wallner

Do biological cells sense time by the number of their divisions, a process that ends at senescence? We consider the question "can the cell's perception of time be expressed through the length of the shortest telomere?" The answer is that…

Subcellular Processes · Quantitative Biology 2017-11-15 Zeev Schuss , Kimsy Tor , David Holcman

Oversight in medical images is a crucial problem, and timely reporting of medical images is desired. Therefore, an all-purpose anomaly detection method that can detect virtually all types of lesions/diseases in a given image is strongly…

Image and Video Processing · Electrical Eng. & Systems 2020-10-21 H. Shibata , S. Hanaoka , Y. Nomura , T. Nakao , I. Sato , D. Sato , N. Hayashi , O. Abe