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The widespread adoption of generative AI models has raised growing concerns about representational harm and potential discriminatory outcomes. Yet, despite growing literature on this topic, the mechanisms by which bias emerges - especially…
The population density and per-generation dispersal rate of a population are central parameters in the study of evolution and ecology. The distribution of recent coalescent events between individuals in space can be used to estimate such…
The constant rate birth--death process is a popular null model for speciation and extinction. If one removes extinct and non-sampled lineages, this process induces `reconstructed trees' which describe the relationship between extant…
Information on the number and category of cervical cells is crucial for the diagnosis of cervical cancer. However, existing classification methods capable of automatically measuring this information require the training dataset to be…
The goal in semi-supervised learning is to effectively combine labeled and unlabeled data. One way to do this is by encouraging smoothness across edges in a graph whose nodes correspond to input examples. In many graph-based methods, labels…
Based on an idea in [4] we propose a new iterative multiplicative filtering algorithm for label assignment matrices which can be used for the supervised partitioning of data. Starting with a row-normalized matrix containing the averaged…
Time-series generated by end-users, edge devices, and different wearables are mostly unlabelled. We propose a method to auto-generate labels of un-labelled time-series, exploiting very few representative labelled time-series. Our method is…
Multipotent stem or progenitor cells undergo a sequential series of binary fate decisions, which ultimately generate the diversity of differentiated cells. Efforts to understand cell fate control have focused on simple gene regulatory…
We employ the framework of multitype Galton-Watson processes to model a population of dividing cells. The cellular type is represented by its biological age, defined as the count of harmful proteins hosted by the cell. The stochastic…
We wish to estimate the total number of classes in a population based on sample counts, especially in the presence of high latent diversity. Drawing on probability theory that characterizes distributions on the integers by ratios of…
The deluge of single-cell data obtained by sequencing, imaging and epigenetic markers has led to an increasingly detailed description of cell state. However, it remains challenging to identify how cells transition between different states,…
The progress in imaging techniques have allowed the study of various aspect of cellular mechanisms. To isolate individual cells in live imaging data, we introduce an elegant image segmentation framework that effectively extracts cell…
Heterogeneity in physical and functional characteristics of cells (e.g. size, cycle time, growth rate, protein concentration) proliferates within an isogenic population due to stochasticity in intracellular biochemical processes and in the…
Graph-based semi-supervised learning usually involves two separate stages, constructing an affinity graph and then propagating labels for transductive inference on the graph. It is suboptimal to solve them independently, as the correlation…
This paper considers the identification of dynamic treatment effects with panel data, in complex designs where the treatment may not be binary and may not be absorbing. We first show that under no-anticipation and parallel-trends…
Single-cell experiments revealed substantial variability in generation times, growth rates but also in birth and division sizes between genetically identical cells. Understanding how these fluctuations determine the fitness of the…
This note describes a new approach to classifying graphs that leverages graph generative models (GGM). Assuming a GGM that defines a joint probability distribution over graphs and their class labels, I derive classification formulas for the…
Active Learning (AL) is increasingly important in a broad range of applications. Two main AL principles to obtain accurate classification with few labeled data are refinement of the current decision boundary and exploration of poorly…
An increasing number of public datasets have shown a transformative impact on automated medical segmentation. However, these datasets are often with varying label quality, ranging from manual expert annotations to AI-generated…
Classification is a vital tool that is important for modelling many complex numerical models. A model or system may be such that, for certain areas of input space, the output either does not exist, or is not in a quantifiable form. Here, we…