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Imaging genetics is a growing field that employs structural or functional neuroimaging techniques to study individuals with genetic risk variants potentially linked to specific illnesses. This area presents considerable challenges to…
Recent advances in neuroimaging analysis have enabled accurate decoding of mental state from brain activation patterns during functional magnetic resonance imaging scans. A commonly applied tool for this purpose is principal components…
Coordinate-based meta-analysis combines evidence from a collection of Neuroimaging studies to estimate brain activation. In such analyses, a key practical challenge is to find a computationally efficient approach with good statistical…
In this paper, we propose an efficient clustering technique to solve the problem of clustering in the presence of obstacles. The proposed algorithm divides the spatial area into rectangular cells. Each cell is associated with statistical…
This work considers a continuous framework to characterize the population-level variability of structural connectivity. Our framework assumes the observed white matter fiber tract endpoints are driven by a latent random function defined…
Substantial evidence indicates that major psychiatric disorders are associated with distributed neural dysconnectivity, leading to strong interest in using neuroimaging methods to accurately predict disorder status. In this work, we are…
Recent advancements in neurotechnology enable precise spatiotemporal patterns of microstimulations with single-cell resolution. The choice of perturbation sites must satisfy two key criteria: efficacy in evoking significant responses and…
In recent years, there has been strong interest in neuroscience studies to investigate brain organization through networks of brain regions that demonstrate strong functional connectivity (FC). These networks are extracted from observed…
Multi-label image classification, which can be categorized into label-dependency and region-based methods, is a challenging problem due to the complex underlying object layouts. Although region-based methods are less likely to encounter…
This paper begins with considering the identification of sparse linear time-invariant networks described by multivariable ARX models. Such models possess relatively simple structure thus used as a benchmark to promote further research. With…
We consider the detection of multivariate spatial clusters in the Bernoulli model with $N$ locations, where the design distribution has weakly dependent marginals. The locations are scanned with a rectangular window with sides parallel to…
Diffusion Tensor Imaging (DTI) is an effective tool for the analysis of structural brain connectivity in normal development and in a broad range of brain disorders. However efforts to derive inherent characteristics of structural brain…
In this paper, region based and location based retrieval systems have been implemented for retrieval of MR-T2 axial 2-D brain images. This is done by extracting and characterizing the tumor portion of 2-D brain slices by use of a suitable…
In various applications with large spatial regions, the relationship between the response variable and the covariates is expected to exhibit complex spatial patterns. We propose a spatially clustered varying coefficient model, where the…
Consider a structured dataset of features, such as $\{\textrm{SEX}, \textrm{INCOME}, \textrm{RACE}, \textrm{EXPERIENCE}\}$. A user may want to know where in the feature space observations are concentrated, and where it is sparse or empty.…
We propose a novel probabilistic dimensionality reduction framework that can naturally integrate the generative model and the locality information of data. Based on this framework, we present a new model, which is able to learn a smooth…
Neural networks are hypothesized to implement interpretable causal mechanisms, yet verifying this requires finding a causal abstraction -- a simpler, high-level Structural Causal Model (SCM) faithful to the network under interventions.…
The representation of images in the brain is known to be sparse. That is, as neural activity is recorded in a visual area ---for instance the primary visual cortex of primates--- only a few neurons are active at a given time with respect to…
Continuous attractor networks (CANs) are widely used to model how the brain temporarily retains continuous behavioural variables via persistent recurrent activity, such as an animal's position in an environment. However, this memory…
Deep neural networks have become widely used, obtaining remarkable results in domains such as computer vision, speech recognition, natural language processing, audio recognition, social network filtering, machine translation, and…