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Accurate and reproducible brain morphometry from structural MRI is critical for monitoring neuroanatomical changes across time and across imaging domains. Although deep learning has accelerated segmentation workflows, scanner-induced…

Computer Vision and Pattern Recognition · Computer Science 2025-04-23 Ekaterina Kondrateva , Sandzhi Barg , Mikhail Vasiliev

Functional magnetic resonance imaging (fMRI) produces data about activity inside the brain, from which spatial maps can be extracted by independent component analysis (ICA). In datasets, there are n spatial maps that contain p voxels. The…

Computational Engineering, Finance, and Science · Computer Science 2016-11-17 Tuomo Sipola , Fengyu Cong , Tapani Ristaniemi , Vinoo Alluri , Petri Toiviainen , Elvira Brattico , Asoke K. Nandi

We investigate the sparse functional identification of complex cells and the decoding of visual stimuli encoded by an ensemble of complex cells. The reconstruction algorithm of both temporal and spatio-temporal stimuli is formulated as a…

Neurons and Cognition · Quantitative Biology 2017-06-20 Aurel A. Lazar , Nikul H. Ukani , Yiyin Zhou

Human brain structural networks contain sets of centrally embedded hub regions that enable efficient information communication. However, it remains largely unknown about categories of structural brain hubs and their microstructural,…

Neurons and Cognition · Quantitative Biology 2016-09-13 Xindi Wang , Qixiang Lin , Mingrui Xia , Yong He

Researchers in functional neuroimaging mostly use activation coordinates to formulate their hypotheses. Instead, we propose to use the full statistical images to define regions of interest (ROIs). This paper presents two machine learning…

Machine Learning · Statistics 2012-09-10 Yannick Schwartz , Gaël Varoquaux , Bertrand Thirion

Tabular datasets with low-sample-size or many variables are prevalent in biomedicine. Practitioners in this domain prefer linear or tree-based models over neural networks since the latter are harder to interpret and tend to overfit when…

Machine Learning · Computer Science 2022-02-09 Junchen Yang , Ofir Lindenbaum , Yuval Kluger

Neural demyelination and brain damage accumulated in white matter appear as hyperintense areas on T2-weighted MRI scans in the form of lesions. Modeling binary images at the population level, where each voxel represents the existence of a…

Methodology · Statistics 2023-05-29 Anna Menacher , Thomas E. Nichols , Chris Holmes , Habib Ganjgahi

Sparse systems are usually parameterized by a tuning parameter that determines the sparsity of the system. How to choose the right tuning parameter is a fundamental and difficult problem in learning the sparse system. In this paper, by…

Methodology · Statistics 2019-01-18 Moo K. Chung , Jamie L. Hanson , Jieping Ye , Richard J. Davidson , Seth D. Pollak

Sparse deep learning aims to address the challenge of huge storage consumption by deep neural networks, and to recover the sparse structure of target functions. Although tremendous empirical successes have been achieved, most sparse deep…

Machine Learning · Statistics 2020-11-17 Jincheng Bai , Qifan Song , Guang Cheng

Feature selection is one of the most decisive tools in understanding data and machine learning models. Among other methods, sparsity induced by $L^{1}$ penalty is one of the simplest and best studied approaches to this problem. Although…

Machine Learning · Computer Science 2020-07-09 Andrii Trelin , Aleš Procházka

Category-selectivity in the brain describes the observation that certain spatially localized areas of the cerebral cortex tend to respond robustly and selectively to stimuli from specific limited categories. One of the most well known…

Neurons and Cognition · Quantitative Biology 2021-12-21 T. Anderson Keller , Qinghe Gao , Max Welling

Active learning enables the efficient construction of a labeled dataset by labeling informative samples from an unlabeled dataset. In a real-world active learning scenario, considering the diversity of the selected samples is crucial…

Machine Learning · Computer Science 2022-07-15 Yeachan Kim , Bonggun Shin

Segmenting healthy tissue structures alongside lesions in brain Magnetic Resonance Images (MRI) remains a challenge for today's algorithms due to lesion-caused disruption of the anatomy and lack of jointly labeled training datasets, where…

Image and Video Processing · Electrical Eng. & Systems 2025-03-26 Meva Himmetoglu , Ilja Ciernik , Ender Konukoglu

In this article, we study association between the structural connectome and cognitive profiles using a multi-response nonparametric regression model.The cognitive profiles are measured in terms of seven age-adjusted cognitive test scores.…

Methodology · Statistics 2022-12-06 Arkaprava Roy

Physics-informed neural networks have emerged as a powerful tool in the scientific machine learning community, with applications to both forward and inverse problems. While they have shown considerable empirical success, significant…

Optimization and Control · Mathematics 2025-12-11 Federica Caforio , Martin Holler , Matthias Höfler

We propose a method for variable selection in the intensity function of spatial point processes that combines sparsity-promoting estimation with noise-robust model selection. As high-resolution spatial data becomes increasingly available…

Methodology · Statistics 2025-10-30 Dominik Sturm , Ivo F. Sbalzarini

The recent wide adoption of Electronic Medical Records (EMR) presents great opportunities and challenges for data mining. The EMR data is largely temporal, often noisy, irregular and high dimensional. This paper constructs a novel ordinal…

Applications · Statistics 2014-07-24 Truyen Tran , Dinh Phung , Wei Luo , Svetha Venkatesh

Being able to adequately process and combine data arising from different sites is crucial in neuroimaging, but is difficult, owing to site, sequence and acquisition-parameter dependent biases. It is important therefore to design algorithms…

Image and Video Processing · Electrical Eng. & Systems 2021-11-05 Pedro Borges , Richard Shaw , Thomas Varsavsky , Kerstin Klaser , David Thomas , Ivana Drobnjak , Sebastien Ourselin , M Jorge Cardoso

Inspired by the robustness and efficiency of sparse representation in sparse coding based image restoration models, we investigate the sparsity of neurons in deep networks. Our method structurally enforces sparsity constraints upon hidden…

Computer Vision and Pattern Recognition · Computer Science 2020-06-09 Yuchen Fan , Jiahui Yu , Yiqun Mei , Yulun Zhang , Yun Fu , Ding Liu , Thomas S. Huang

Understanding the complex structure of multivariate extremes is a major challenge in various fields from portfolio monitoring and environmental risk management to insurance. In the framework of multivariate Extreme Value Theory, a common…

Machine Learning · Statistics 2021-02-09 Hamid Jalalzai , Rémi Leluc