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The human brain is a complex and highly dynamic system, and our current knowledge of its functional mechanism is still very limited. Fortunately, with functional magnetic resonance imaging (fMRI), we can observe blood oxygen level-dependent…

Neurons and Cognition · Quantitative Biology 2024-12-31 Yifei Sun , Mariano Cabezas , Jiah Lee , Chenyu Wang , Wei Zhang , Fernando Calamante , Jinglei Lv

To maintain coherence in language, the brain must satisfy key competing temporal demands: the gradual accumulation of meaning across extended context (drift) and the rapid reconfiguration of representations at event boundaries (shift). How…

Hidden Markov models (HMMs) and conditional random fields (CRFs) are two popular techniques for modeling sequential data. Inference algorithms designed over CRFs and HMMs allow estimation of the state sequence given the observations. In…

Artificial Intelligence · Computer Science 2012-02-20 Gungor Polatkan , Oncel Tuzel

MRI-based brain age estimation models aim to assess a subject's biological brain age based on information, such as neuroanatomical features. Various factors, including neurodegenerative diseases, can accelerate brain aging and measuring…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Simon Joseph Clément Crête , Marta Kersten-Oertel , Yiming Xiao

In this article, we study association between the structural connectome and cognitive profiles using a multi-response nonparametric regression model.The cognitive profiles are measured in terms of seven age-adjusted cognitive test scores.…

Methodology · Statistics 2022-12-06 Arkaprava Roy

Functional brain imaging through electroencephalography (EEG) relies upon the analysis and interpretation of high-dimensional, spatially organized time series. We propose to represent time-localized frequency domain characterizations of EEG…

Understanding the dynamic reorganization of brain networks is critical for predicting cognitive decline, neurological progression, and individual variability in clinical outcomes. This work proposes a multimodal graph neural network…

Machine Learning · Computer Science 2026-02-11 Preksha Girish , Rachana Mysore , Kiran K. N. , Hiranmayee R. , Shipra Prashanth , Shrey Kumar

A cornerstone of human statistical learning is the ability to extract temporal regularities / patterns from random sequences. Here we present a method of computing pattern time statistics with generating functions for first-order Markov…

Neurons and Cognition · Quantitative Biology 2018-06-29 Yanlong Sun , Hongbin Wang

We study the distribution of brain source from the most advanced brain imaging technique, Magnetoencephalography (MEG), which measures the magnetic fields outside the human head produced by the electrical activity inside the brain. Common…

Applications · Statistics 2019-08-13 Zhigang Yao , Zengyan Fan , Masahito Hayashi , William F. Eddy

Electronic health records contain valuable information for monitoring patients' health trajectories over time. Disease progression models have been developed to understand the underlying patterns and dynamics of diseases using these data as…

This paper addresses the problem of video object segmentation, where the initial object mask is given in the first frame of an input video. We propose a novel spatio-temporal Markov Random Field (MRF) model defined over pixels to handle…

Computer Vision and Pattern Recognition · Computer Science 2018-03-28 Linchao Bao , Baoyuan Wu , Wei Liu

Both resources in the natural environment and concepts in a semantic space are distributed "patchily", with large gaps in between the patches. To describe people's internal and external foraging behavior, various random walk models have…

Machine Learning · Computer Science 2017-10-17 Jian-Qiao Zhu , Adam N. Sanborn , Nick Chater

Deep learning has proven to successfully learn variations in tissue and cell morphology. Training of such models typically relies on expensive manual annotations. Here we conjecture that spatially resolved gene expression, e.i., the…

Quantitative Methods · Quantitative Biology 2023-12-11 Axel Andersson , Gabriele Partel , Leslie Solorzano , Carolina Wählby

This paper focuses on the analysis of sequential image data, particularly brain imaging data such as MRI, fMRI, CT, with the motivation of understanding the brain aging process and neurodegenerative diseases. To achieve this goal, we…

Machine Learning · Statistics 2024-07-22 Zhenghao Li , Sanyou Wu , Long Feng

We demonstrate the use of a multidimensional extension of the latent Markov model to analyse data from studies with correlated binary responses in developmental psychology. In particular, we consider an experiment based on a battery of…

Applications · Statistics 2025-01-08 Francesco Bartolucci , Ivonne L. Solis-Trapala

Electroencephalogram (EEG) signals play a pivotal role in biomedical research and clinical applications, including epilepsy diagnosis, sleep disorder analysis, and brain-computer interfaces. However, the effective analysis and…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Jiahao Qin , Feng Liu

Non-invasive measurements of the human brain using magnetic resonance imaging (MRI) have significantly improved our understanding the brain's network organization by enabling measurement of anatomical connections between brain regions…

Applications · Statistics 2025-12-10 Keshav Motwani , Ali Shojaie , Ariel Rokem , Eardi Lila

A core goal of functional neuroimaging is to study how the environment is processed in the brain. The mainstream paradigm involves concurrently measuring a broad spectrum of brain responses to a small set of environmental features…

Neurons and Cognition · Quantitative Biology 2021-06-14 Pedro F. da Costa , Rianne Haartsen , Elena Throm , Luke Mason , Anna Gui , Robert Leech , Emily J. H. Jones

Mean field models (MFMs) of cortical tissue incorporate salient features of neural masses to model activity at the population level. One of the common aspects of MFM descriptions is the presence of a high dimensional parameter space…

Dynamical Systems · Mathematics 2015-05-19 Federico Frascoli , Lennaert van Veen , Ingo Bojak , David T J Liley

Probabilistic graphical models, such as Markov random fields (MRFs), are useful for describing high-dimensional distributions in terms of local dependence structures. The probabilistic inference is a fundamental problem related to graphical…

Data Structures and Algorithms · Computer Science 2020-11-30 Weiming Feng , Kun He , Xiaoming Sun , Yitong Yin