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Motivation: Biological data and knowledge bases increasingly rely on Semantic Web technologies and the use of knowledge graphs for data integration, retrieval and federated queries. In the past years, feature learning methods that are…

Quantitative Methods · Quantitative Biology 2017-05-01 Mona Alshahrani , Mohammed Asif Khan , Omar Maddouri , Akira R Kinjo , Núria Queralt-Rosinach , Robert Hoehndorf

This paper presents an overview of current research concerning knowledge extraction from technical texts. In particular, the use of empirical techniques during the identification and generation of a semantic representation is considered. A…

cmp-lg · Computer Science 2008-02-03 Robin Collier

Nowadays, the amount of heterogeneous biomedical data is increasing more and more thanks to novel sensing techniques and high-throughput technologies. In reference to biomedical image analysis, the advances in image acquisition modalities…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Leonardo Rundo

With the advancement of high-throughput biotechnologies, we increasingly accumulate biomedical data about diseases, especially cancer. There is a need for computational models and methods to sift through, integrate, and extract new…

Quantitative Methods · Quantitative Biology 2020-07-03 Thomas Gaudelet , Noel Malod-Dognin , Natasa Przulj

The difficulties of automatic extraction of definitions and methods from scientific documents lie in two aspects: (1) the complexity and diversity of natural language texts, which requests an analysis method to support the discovery of…

Computation and Language · Computer Science 2023-07-06 Yutian Sun , Hai Zhuge

Diseases involve complex processes and modifications to the cellular machinery. The gene expression profile of the affected cells contains characteristic patterns linked to a disease. Hence, biological knowledge pertaining to a disease can…

Quantitative Methods · Quantitative Biology 2020-04-13 Thomas Gaudelet , Noel Malod-Dognin , Jon Sanchez-Valle , Vera Pancaldi , Alfonso Valencia , Natasa Przulj

Extraction of concepts present in patient clinical records is an essential step in clinical research. The 2010 i2b2/VA Workshop on Natural Language Processing Challenges for clinical records presented concept extraction (CE) task, with aim…

Computation and Language · Computer Science 2016-10-20 Raghavendra Chalapathy , Ehsan Zare Borzeshi , Massimo Piccardi

One of the defining features of living systems is their adaptability to changing environmental conditions. This requires organisms to extract temporal and spatial features of their environment, and use that information to compute the…

Neurons and Cognition · Quantitative Biology 2024-02-27 Maria Sol Vidal-Saez , Oscar Vilarroya , Jordi Garcia-Ojalvo

Formal concepts and closed itemsets proved to be of big importance for knowledge discovery, both as a tool for concise representation of association rules and a tool for clustering and constructing domain taxonomies and ontologies.…

Artificial Intelligence · Computer Science 2017-04-21 Sergei O. Kuznetsov , Tatiana Makhalova

When performing a conceptual analysis of a concept, philosophers are interested in all forms of expression of a concept in a text---be it direct or indirect, explicit or implicit. In this paper, we experiment with topic-based methods of…

Computation and Language · Computer Science 2017-06-20 Louis Chartrand , Jackie C. K. Cheung , Mohamed Bouguessa

A steadily growing computational power is employed to perform molecular dynamics simulations of biological macromolecules, which represents at the same time an immense opportunity and a formidable challenge. In fact, large amounts of data…

Soft Condensed Matter · Physics 2022-05-18 Margherita Mele , Roberto Covino , Raffaello Potestio

Biological science produces large amounts of data in a variety of formats, which necessitates the use of computational tools to process, integrate, analyse, and glean insights from the data. Researchers who use computational biology tools…

Human-Computer Interaction · Computer Science 2024-05-10 Yo Yehudi , Lukas Hughes-Noehrer , Carole Goble , Caroline Jay

Knowledge base question answering (KBQA) aims to answer user questions in natural language using rich human knowledge stored in large KBs. As current KBQA methods struggle with unseen knowledge base elements at test time,we introduce…

Computation and Language · Computer Science 2025-09-11 Shengxiang Gao , Jey Han Lau , Jianzhong Qi

The increasing volume of scholarly publications requires advanced tools for efficient knowledge discovery and management. This paper introduces ongoing work on a system using Large Language Models (LLMs) for the semantic extraction of key…

Digital Libraries · Computer Science 2025-10-07 Samy Ateia , Udo Kruschwitz , Melanie Scholz , Agnes Koschmider , Moayad Almohaishi

Machine learning is a modern approach to problem-solving and task automation. In particular, machine learning is concerned with the development and applications of algorithms that can recognize patterns in data and use them for predictive…

We advocate the use of qualitative models in the analysis of large biological systems. We show how qualitative models are linked to theoretical differential models and practical graphical models of biological networks. A new technique for…

Molecular Networks · Quantitative Biology 2007-05-23 Philippe Veber , Michel Le_Borgne , Anne Siegel , Sandrine Lagarrigue , Ovidiu Radulescu

Assessing where and how information is stored in biological networks (such as neuronal and genetic networks) is a central task both in neuroscience and in molecular genetics, but most available tools focus on the network's structure as…

Information Theory · Computer Science 2023-02-24 Clifford Bohm , Douglas Kirkpatrick , Victoria Cao , Christoph Adami

Computational biology is on the verge of a paradigm shift in its research practice - from a data-based (computational) paradigm to an information-based (cognitive) paradigm. As in the other research fields, this transition is impeded by…

Other Computer Science · Computer Science 2015-05-21 Emanuel Diamant

Motivation: ``Molecular signatures'' or ``gene-expression signatures'' are used to predict patients' characteristics using data from coexpressed genes. Signatures can enhance understanding about biological mechanisms and have diagnostic…

Quantitative Methods · Quantitative Biology 2007-05-23 Ramon Diaz-Uriarte

The black-box nature of deep learning models prevents them from being completely trusted in domains like biomedicine. Most explainability techniques do not capture the concept-based reasoning that human beings follow. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2022-03-15 Avinash Kori , Parth Natekar , Ganapathy Krishnamurthi , Balaji Srinivasan
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