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Functional data clustering is to identify heterogeneous morphological patterns in the continuous functions underlying the discrete measurements/observations. Application of functional data clustering has appeared in many publications across…

Methodology · Statistics 2022-10-04 Mimi Zhang , Andrew Parnell

There is a large number of online documents data sources available nowadays. The lack of structure and the differences between formats are the main difficulties to automatically extract information from them, which also has a negative…

Genomic data visualization is essential for interpretation and hypothesis generation as well as a valuable aid in communicating discoveries. Visual tools bridge the gap between algorithmic approaches and the cognitive skills of…

Genomics · Quantitative Biology 2019-11-04 Sabrina Nusrat , Theresa Harbig , Nils Gehlenborg

Due to the large volume of data and information generated by a multitude of social data sources, it is a huge challenge to manage and extract useful knowledge, especially given the different forms of data, streaming data and uncertainty and…

Databases · Computer Science 2021-05-10 Bilal Abu-Salih , Pornpit Wongthongtham , Dengya Zhu , Kit Yan Chan , Amit Rudra

The rapid advancement of large language models (LLMs) has opened new boundaries in the extraction and synthesis of medical knowledge, particularly within evidence synthesis. This paper reviews the state-of-the-art applications of LLMs in…

In the biotechnology and biomedical domains, recent text mining efforts advocate for machine-interpretable, and preferably, semantified, documentation formats of laboratory processes. This includes wet-lab protocols, (in)organic materials…

Digital Libraries · Computer Science 2020-09-17 Marco Anteghini , Jennifer D'Souza , Vitor A. P. Martins dos Santos , Sören Auer

We compare two distinct approaches for querying data in the context of the life sciences. The first approach utilizes conventional databases to store the data and intuitive form-based interfaces to facilitate easy querying of the data.…

Information Retrieval · Computer Science 2012-10-03 Amir H. Asiaee , Prashant Doshi , Todd Minning , Satya Sahoo , Priti Parikh , Amit Sheth , Rick L. Tarleton

RNA-sequencing (RNA-seq) has become an exemplar technology in modern biology and clinical applications over the past decade. It has gained immense popularity in the recent years driven by continuous efforts of the bioinformatics community…

We present the Thought Graph as a novel framework to support complex reasoning and use gene set analysis as an example to uncover semantic relationships between biological processes. Our framework stands out for its ability to provide a…

Computation and Language · Computer Science 2024-03-13 Chi-Yang Hsu , Kyle Cox , Jiawei Xu , Zhen Tan , Tianhua Zhai , Mengzhou Hu , Dexter Pratt , Tianlong Chen , Ziniu Hu , Ying Ding

Using different sources of information to support automated extracting of relations between biomedical concepts contributes to the development of our understanding of biological systems. The primary comprehensive source of these relations…

Computation and Language · Computer Science 2020-09-21 Diana Sousa , Andre Lamurias , Francisco M. Couto

Background Concept extraction, a subdomain of natural language processing (NLP) with a focus on extracting concepts of interest, has been adopted to computationally extract clinical information from text for a wide range of applications…

Modern research in the life sciences is unthinkable without computational methods for extracting, quantifying and visualizing information derived from biological microscopy imaging data. In the past decade, we observed a dramatic increase…

Both experimental and computational biology is becoming increasingly automated. Laboratory experiments are now performed automatically on high-throughput machinery, while computational models are synthesized or inferred automatically from…

Programming Languages · Computer Science 2018-05-08 Alessandro Abate , Luca Cardelli , Marta Kwiatkowska , Luca Laurenti , Boyan Yordanov

Biomedical research centers can empower basic discovery and novel therapeutic strategies by leveraging their large-scale datasets from experiments and patients. This data, together with new technologies to create and analyze it, has ushered…

In this chapter tools and techniques from the mathematical theory of formal concept analysis are applied to hypertext systems in general, and the World Wide Web in particular. Various processes for the conceptual structuring of hypertext…

Artificial Intelligence · Computer Science 2018-10-18 Robert E. Kent , Christian Neuss

Knowledge mining is the process of deriving new and useful knowledge from vast volumes of data and background knowledge. Modern healthcare organizations regularly generate huge amount of electronic data stored in the databases. These data…

Logic in Computer Science · Computer Science 2011-07-26 Nittaya Kerdprasop , Kittisak Kerdprasop

The correlation and interactions among different biological entities comprise the biological system. Although already revealed interactions contribute to the understanding of different existing systems, researchers face many questions…

Information Retrieval · Computer Science 2014-01-14 Md. Naseef-Ur-Rahman Chowdhury , Suvankar Paul , Kazi Zakia Sultana

Biomedical information extraction (BioIE) is important to many applications, including clinical decision support, integrative biology, and pharmacovigilance, and therefore it has been an active research. Unlike existing reviews covering a…

Computation and Language · Computer Science 2016-06-28 Feifan Liu , Jinying Chen , Abhyuday Jagannatha , Hong Yu

Interpretability has become an essential topic for artificial intelligence in some high-risk domains such as healthcare, bank and security. For commonly-used tabular data, traditional methods trained end-to-end machine learning models with…

Artificial Intelligence · Computer Science 2022-08-18 Haixiao Chi , Dawei Wang , Gaojie Cui , Feng Mao , Beishui Liao

Textual queries are largely employed in information retrieval to let users specify search goals in a natural way. However, differences in user and system terminologies can challenge the identification of the user's information needs, and…

Information Retrieval · Computer Science 2020-03-31 Noemi Mauro , Liliana Ardissono , Adriano Savoca