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The poor contrast and the overlapping of cervical cell cytoplasm are the major issues in the accurate segmentation of cervical cell cytoplasm. This paper presents an automated unsupervised cytoplasm segmentation approach which can…

Computer Vision and Pattern Recognition · Computer Science 2018-07-16 Pranav Kumar , S L Happy , Swarnadip Chatterjee , Debdoot Sheet , Aurobinda Routray

Segmenting overlapping cytoplasm of cells in cervical smear images is a clinically essential task, for quantitatively measuring cell-level features in order to diagnose cervical cancer. This task, however, remains rather challenging, mainly…

Computer Vision and Pattern Recognition · Computer Science 2020-04-16 Youyi Song , Lei Zhu , Baiying Lei , Bin Sheng , Qi Dou , Jing Qin , Kup-Sze Choi

In the effort to aid cytologic diagnostics by establishing automatic single cell screening using high throughput digital holographic microscopy for clinical studies thousands of images and millions of cells are captured. The bottleneck lies…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Julia Sistermanns , Ellen Emken , Gregor Weirich , Oliver Hayden , Wolfgang Utschick

This paper presents a method that improve state-of-the-art of the concave point detection methods as a first step to segment overlapping objects on images. It is based on the analysis of the curvature of the objects contour. The method has…

Computer Vision and Pattern Recognition · Computer Science 2022-01-11 Miquel Miró-Nicolau , Biel Moyà-Alcover , Manuel Gonzàlez-Hidalgo , Antoni Jaume-i-Capó

When applying automatic analysis of fluorescence or histopathological images of cells, it is necessary to partition, or de-clump, partially overlapping cell nuclei. In this work, I describe a method of partitioning partially overlapping…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 James Kapaldo

In medicine, visualizing chromosomes is important for medical diagnostics, drug development, and biomedical research. Unfortunately, chromosomes often overlap and it is necessary to identify and distinguish between the overlapping…

Computer Vision and Pattern Recognition · Computer Science 2017-12-21 R. Lily Hu , Jeremy Karnowski , Ross Fadely , Jean-Patrick Pommier

Pap smear testing has been widely used for detecting cervical cancers based on the morphology properties of cell nuclei in microscopic image. An accurate nuclei segmentation could thus improve the success rate of cervical cancer screening.…

Computer Vision and Pattern Recognition · Computer Science 2019-05-15 Jie Zhao , Quanzheng Li , Xiang Li , Hongfeng Li , Li Zhang

Highly clumped nuclei clusters captured in fluorescence in situ hybridization microscopy images are common histology entities under investigations in a wide spectrum of tissue-related biomedical investigations. Due to their large scale in…

Computer Vision and Pattern Recognition · Computer Science 2018-08-15 Xiaoyuan Guo , Hanyi Yu , Blair Rossetti , George Teodoro , Daniel Brat , Jun Kong

The unsupervised segmentation is an increasingly popular topic in biomedical image analysis. The basic idea is to approach the supervised segmentation task as an unsupervised synthesis problem, where the intensity images can be transferred…

Computer Vision and Pattern Recognition · Computer Science 2020-10-23 Quan Liu , Isabella M. Gaeta , Bryan A. Millis , Matthew J. Tyska , Yuankai Huo

To separate the overlapped cells, a bottleneck detection approach is proposed in this paper. The cell image is segmented by slope difference distribution (SDD) threshold selection. For each segmented binary clump, its one-dimensional…

Computer Vision and Pattern Recognition · Computer Science 2019-12-12 ZhenZhou Wang

Instance segmentation aims to delineate each individual object of interest in an image. State-of-the-art approaches achieve this goal by either partitioning semantic segmentations or refining coarse representations of detected objects. In…

Computer Vision and Pattern Recognition · Computer Science 2022-10-10 Long Chen , Yuli Wu , Dorit Merhof

We report results on unsupervised organization of cervical cells using microscopy of Pap-smear samples in brightfield (3-channel colour) as well as high resolution quantitative phase imaging modalities. A number of morphological parameters…

Image and Video Processing · Electrical Eng. & Systems 2018-11-14 Jyoti Mangal , Rashi Monga , Sandeep R. Mathur , Amit K. Dinda , Joby Joseph , Sarita Ahlawat , Kedar Khare

Automation-assisted cervical screening via Pap smear or liquid-based cytology (LBC) is a highly effective cell imaging based cancer detection tool, where cells are partitioned into "abnormal" and "normal" categories. However, the success of…

Computer Vision and Pattern Recognition · Computer Science 2018-01-29 Ling Zhang , Le Lu , Isabella Nogues , Ronald M. Summers , Shaoxiong Liu , Jianhua Yao

This paper presents a novel unsupervised segmentation method for 3D medical images. Convolutional neural networks (CNNs) have brought significant advances in image segmentation. However, most of the recent methods rely on supervised…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Takayasu Moriya , Holger R. Roth , Shota Nakamura , Hirohisa Oda , Kai Nagara , Masahiro Oda , Kensaku Mori

Automated detection of cervical cancer cells or cell clumps has the potential to significantly reduce error rate and increase productivity in cervical cancer screening. However, most traditional methods rely on the success of accurate cell…

Computer Vision and Pattern Recognition · Computer Science 2019-12-24 Yixiong Liang , Zhihong Tang , Meng Yan , Jialin Chen , Qing Liu , Yao Xiang

Accurate segmentation of ultrasound (US) images of the cervical muscles is crucial for precision healthcare. The demand for automatic computer-assisted methods is high. However, the scarcity of labeled data hinders the development of these…

Image and Video Processing · Electrical Eng. & Systems 2025-03-24 Fangyijie Wang , Kathleen M. Curran , Guénolé Silvestre

While most previous automation-assisted reading methods can improve efficiency, their performance often relies on the success of accurate cell segmentation and hand-craft feature extraction. This paper presents an efficient and totally…

Computer Vision and Pattern Recognition · Computer Science 2019-12-17 Yao Xiang , Wanxin Sun , Changli Pan , Meng Yan , Zhihua Yin , Yixiong Liang

Analyzing Pap cytology slides is an important tasks in detecting and grading precancerous and cancerous cervical cancer stages. Processing cytology images usually involve segmenting nuclei and overlapping cells. We introduce a cervical…

Computer Vision and Pattern Recognition · Computer Science 2018-11-27 Hady Ahmady Phoulady , Peter R. Mouton

Locating the center of convex objects is important in both image processing and unsupervised machine learning/data clustering fields. The automated analysis of biological images uses both of these fields for locating cell nuclei and for…

Computer Vision and Pattern Recognition · Computer Science 2018-04-12 James Kapaldo , Xu Han , Domingo Mery

Cell instance segmentation in Pap smear image remains challenging due to the wide existence of occlusion among translucent cytoplasm in cell clumps. Conventional methods heavily rely on accurate nuclei detection results and are easily…

Computer Vision and Pattern Recognition · Computer Science 2019-08-20 Yanning Zhou , Hao Chen , Jiaqi Xu , Qi Dou , Pheng-Ann Heng
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