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Automatic detection of abnormal cervical cells from Thinprep Cytologic Test (TCT) images is a critical component in the development of intelligent computer-aided diagnostic systems. However, existing algorithms typically fail to effectively…

Computer Vision and Pattern Recognition · Computer Science 2025-08-25 Jincheng Li , Danyang Dong , Menglin Zheng , Jingbo Zhang , Yueqin Hang , Lichi Zhang , Lili Zhao

Segmentation and accurate localization of nuclei in histopathological images is a very challenging problem, with most existing approaches adopting a supervised strategy. These methods usually rely on manual annotations that require a lot of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-17 Mihir Sahasrabudhe , Stergios Christodoulidis , Roberto Salgado , Stefan Michiels , Sherene Loi , Fabrice André , Nikos Paragios , Maria Vakalopoulou

Segmentation of overlapping convex objects has various applications, for example, in nanoparticles and cell imaging. Often the segmentation method has to rely purely on edges between the background and foreground making the analyzed images…

Computer Vision and Pattern Recognition · Computer Science 2019-06-05 Sahar Zafari , Mariia Murashkina , Tuomas Eerola , Jouni Sampo , Heikki Kälviäinen , Heikki Haario

Segmentation of objects in microscopy images is required for many biomedical applications. We introduce object-centric embeddings (OCEs), which embed image patches such that the spatial offsets between patches cropped from the same object…

Machine Learning · Computer Science 2023-10-13 Steffen Wolf , Manan Lalit , Henry Westmacott , Katie McDole , Jan Funke

Cell instance segmentation in cytology images has significant importance for biology analysis and cancer screening, while remains challenging due to 1) the extensive overlapping translucent cell clusters that cause the ambiguous boundaries,…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Hao Jiang , Rushan Zhang , Yanning Zhou , Yumeng Wang , Hao Chen

Cervical cancer remains a significant health challenge, with high incidence and mortality rates, particularly in transitioning countries. Conventional Liquid-Based Cytology(LBC) is a labor-intensive process, requires expert pathologists and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-30 Love Panta , Suraj Prasai , Karishma Malla Vaidya , Shyam Shrestha , Suresh Manandhar

We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Fidel A. Guerrero-Peña , Pedro D. Marrero Fernandez , Tsang Ing Ren , Alexandre Cunha

Fine-grained classification of cervical cells into different abnormality levels is of great clinical importance but remains very challenging. Contrary to traditional classification methods that rely on hand-crafted or engineered features,…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Haoming Lin , Yuyang Hu , Siping Chen , Jianhua Yao , Ling Zhang

Medical image segmentation methods are generally designed as fully-supervised to guarantee model performance, which require a significant amount of expert annotated samples that are high-cost and laborious. Semi-supervised image…

Computer Vision and Pattern Recognition · Computer Science 2023-10-10 Xiangyu Zhao , Zengxin Qi , Sheng Wang , Qian Wang , Xuehai Wu , Ying Mao , Lichi Zhang

Automated red blood cell (RBC) classification on blood smear images helps hematologists to analyze RBC lab results in a reduced time and cost. However, overlapping cells can cause incorrect predicted results, and so they have to be…

Image and Video Processing · Electrical Eng. & Systems 2024-10-30 Korranat Naruenatthanaset , Thanarat H. Chalidabhongse , Duangdao Palasuwan , Nantheera Anantrasirichai , Attakorn Palasuwan

Chromosome analysis and identification from metaphase images is a critical part of cytogenetics based medical diagnosis. It is mainly used for identifying constitutional, prenatal and acquired abnormalities in the diagnosis of genetic…

Computer Vision and Pattern Recognition · Computer Science 2022-09-13 Amritha S Pallavoor , Prajwal A , Sundareshan TS , Sreekanth K Pallavoor

This paper presents a novel method for unsupervised segmentation of pathology images. Staging of lung cancer is a major factor of prognosis. Measuring the maximum dimensions of the invasive component in a pathology images is an essential…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Takayasu Moriya , Holger R. Roth , Shota Nakamura , Hirohisa Oda , Kai Nagara , Masahiro Oda , Kensaku Mori

Microscopy structure segmentation, such as detecting cells or nuclei, generally requires a human to draw a ground truth contour around each instance. Weakly supervised approaches (e.g. consisting of only single point labels) have the…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 James Willoughby , Irina Voiculescu

Cervical cancer is highly preventable, yet persistent barriers to screening limit progress toward elimination goals. Speculum-free devices that integrate imaging and sampling could improve access, particularly in low-resource settings, but…

Detecting and segmenting individual cells from microscopy images is critical to various life science applications. Traditional cell segmentation tools are often ill-suited for applications in brightfield microscopy due to poor contrast and…

Image and Video Processing · Electrical Eng. & Systems 2020-05-20 Rituparna Sarkar , Suvadip Mukherjee , Elisabeth Labruyère , Jean-Christophe Olivo-Marin

Segmentation is one of the most important tasks in the medical imaging pipeline as it influences a number of image-based decisions. To be effective, fully supervised segmentation approaches require large amounts of manually annotated…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Tyler Ward , Aaron Moseley , Abdullah-Al-Zubaer Imran

In this paper, we propose an approach to the unsupervised segmentation of images using Markov Random Field. The proposed approach is based on the idea of Bit Plane Slicing. We use the planes as initial labellings for an ensemble of…

Computer Vision and Pattern Recognition · Computer Science 2014-10-29 Balint Antal , Bence Remenyik , Andras Hajdu

We propose a novel weakly supervised method to improve the boundary of the 3D segmented nuclei utilizing an over-segmented image. This is motivated by the observation that current state-of-the-art deep learning methods do not result in…

Computer Vision and Pattern Recognition · Computer Science 2021-08-31 S. Shailja , Jiaxiang Jiang , B. S. Manjunath

Significance: Cervical cancer progresses through cervical intraepithelial neoplasia (CIN), which are precursor lesions of cervical cancer. In low-grade CIN, atypical cells generate inside the squamous epithelium, which causes the accuracy…

Cytology screening from Papanicolaou (Pap) smears is a common and effective tool for the preventive clinical management of cervical cancer, where abnormal cell detection from whole slide images serves as the foundation for reporting…

Computer Vision and Pattern Recognition · Computer Science 2024-09-24 Hao Jiang , Runsheng Liu , Yanning Zhou , Huangjing Lin , Hao Chen