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A fluctuation theorem is examined for the first-passage time of a biomolecular machine (e.g., a motor protein or an enzyme) in a nonequilibrium steady-state. For such machines in which the driven, observable process is coupled to a hidden…

Biological Physics · Physics 2025-09-15 D. Evan Piephoff , Jianshu Cao

In chemical reaction networks, bistability can only occur far from equilibrium. It is associated with a first-order phase transition where the control parameter is the thermodynamic force. At the bistable point, the entropy production is…

Statistical Mechanics · Physics 2020-08-11 Basile Nguyen , Udo Seifert

The second law of thermodynamics implies that no macroscopic system may oscillate indefinitely without consuming energy. The question of the number of possible oscillations and the coherent quality of these oscillations remain unanswered.…

Statistical Mechanics · Physics 2011-08-09 Nathan O. Hodas

Giving a universal upper bound on the power output of heat engines is a long-standing open problem. We tackle this problem for generic quantum machines in self-contained formulation by carefully including the switching process of the…

Quantum Physics · Physics 2018-01-03 Kosuke Ito , Takayuki Miyadera

The total entropy production quantifies the extent of irreversibility in thermodynamic systems, which is nonnegative for any feasible dynamics. When additional information such as the initial and final states or moments of an observable is…

Statistical Mechanics · Physics 2020-12-29 Van Tuan Vo , Tan Van Vu , Yoshihiko Hasegawa

We show that, nonlinear optical processes of nanoparticles can be controlled by the presence of interactions with a molecule or a quantum dot. By choosing the appropriate level spacing for the quantum emitter, one can either suppress or…

Mesoscale and Nanoscale Physics · Physics 2014-09-22 Deniz Turkpence , Gursoy B. Akguc , Alpan Bek , Mehmet Emre Tasgin

Gene expression is a random or noisy process. The process consists of several random events among which the reinitiation of transcription by RNAP is an important one. The RNAP molecules can bind the gene only after the promoter gets…

Molecular Networks · Quantitative Biology 2020-08-26 Rajesh Karmakar

When wave scattering systems are subject to certain symmetries, resonant states may decouple from the far-field continuum; they remain localized to the structure and cannot be excited by incident waves from the far field. In this work, we…

Analysis of PDEs · Mathematics 2021-10-27 Habib Ammari , Bryn Davies , Erik Orvehed Hiltunen , Hyundae Lee , Sanghyeon Yu

We extend Fano's inequality, which controls the average probability of events in terms of the average of some $f$--divergences, to work with arbitrary events (not necessarily forming a partition) and even with arbitrary $[0,1]$--valued…

Statistics Theory · Mathematics 2019-06-12 Sebastien Gerchinovitz , Pierre Ménard , Gilles Stoltz

Frequent applications of a mixing quantum operation to a quantum system slow down its time evolution and eventually drive it into the invariant subspace of the named operation. We prove this phenomenon, the quantum Zeno effect, and its…

Quantum Physics · Physics 2024-09-11 Robert Salzmann

We consider electron transport in a quantum wire with a side-coupled quantum ring in a two-dimensional model that accounts for a finite width of the channels. We use the finite difference technique to solve the scattering problem as well as…

Mesoscale and Nanoscale Physics · Physics 2010-10-07 B. Szafran , M. R. Poniedziałek

In this technical note, we give two extensions of the classical Fano inequality in information theory. The first extends Fano's inequality to the setting of estimation, providing lower bounds on the probability that an estimator of a…

Information Theory · Computer Science 2014-01-03 John C. Duchi , Martin J. Wainwright

The thermodynamic uncertainty relation is a prominent result in stochastic thermodynamics that provides a bound on the fluctuations of any thermodynamic flux, also known as current, in terms of the average rate of entropy production. Such…

Statistical Mechanics · Physics 2021-12-22 Taylor Wampler , Andre C Barato

As first suggested by U. Fano in the 1940s, the statistical fluctuation of the number of pairs produced in an ionizing interaction is known to be sub-Poissonian. The dispersion is reduced by the so-called "Fano factor", which empirically…

Instrumentation and Methods for Astrophysics · Physics 2018-11-21 D. Durnford , Q. Arnaud , G. Gerbier

In some non-equilibrium systems, the distribution of entropy production $p(\Sigma)$ satisfies the detailed fluctuation theorem (DFT), $p(\Sigma)/p(-\Sigma)=\exp(\Sigma)$. When the distribution $p(\Sigma)$ shows time-dependency, the…

Statistical Mechanics · Physics 2023-08-21 Domingos S. P. Salazar

Information theory provides tools to predict the performance of a learning algorithm on a given dataset. For instance, the accuracy of learning an unknown parameter can be upper bounded by reducing the learning task to hypothesis testing…

Quantum Physics · Physics 2026-04-21 Evan Peters

Understanding current fluctuations is of fundamental importance and paves the way for the development of practical applications. According to the thermodynamic and kinetic uncertainty relations, the precision of currents can be constrained…

Statistical Mechanics · Physics 2022-10-06 Van Tuan Vo , Tan Van Vu , Yoshihiko Hasegawa

The quantum Zeno effect freezes the evolution of a quantum system subject to frequent measure- ments. We apply a Fisher information analysis to show that because of this effect, a closed quantum system should be probed as rarely as possible…

Quantum Physics · Physics 2015-09-23 Alexander Holm Kiilerich , Klaus Mølmer

Quantum speed limits are relations yielding lower bounds on the evolution time of quantum systems. These results have been generalized in some ways, in particular by including evolutions to non-orthogonal states. However, there was a gap in…

Quantum Physics · Physics 2014-07-17 M. M. Taddei

The celebrated Michaelis-Menten (MM) expression provides a fundamental relation between the rate of enzyme catalysis and substrate concentration. The validity of this classical expression is, however, restricted to macroscopic amounts of…

Biological Physics · Physics 2019-05-09 Arti Dua