Related papers: Feedback Regulation and its Efficiency in Biochemi…
Homeostasis is a running theme in biology. Often achieved through feedback regulation strategies, homeostasis allows living cells to control their internal environment as a means for surviving changing and unfavourable environments. While…
This paper concerns the reliability of a pair of coupled oscillators in response to fluctuating inputs. Reliability means that an input elicits essentially identical responses upon repeated presentations regardless of the network's initial…
We analyze a (symmetrical) two-sensor arrangement with a joint boundary line between the sensors for fluctuation-enhanced sensing. We show a way to separate the adsorption-desorption signal components from the diffusive signal component.…
In this paper, we consider a point-to-point link between an energy harvesting transmitter and receiver, where neither node has the information about the battery state or energy availability at the other node. We consider a model where data…
Cooperative behaviors arising from bacterial cell-to-cell communication can be modeled by reaction-diffusion equations having only a single diffusible component. This paper presents the following three contributions for the systematic…
A recurring motif in gene regulatory networks is transcription factors (TFs) that regulate each other, and then bind to overlapping sites on DNA, where they interact and synergistically control transcription of a target gene. Here, we…
In complex systems, the interplay between network structure and noise often leads to emergent phenomena. This study explores the effects of uneven coupling and asymmetric noise on the dynamics of feed-forward loop (FFL) motifs, essential…
Besides parametric uncertainties and disturbances, the unmodeled dynamics and time delay at the input are often present in practical systems, which cannot be ignored in some cases. This paper aims to solve output feedback tracking control…
What is the most crucial characteristic of a system with life activity? Currently, many theories have attempted to explain the most essential difference between living systems and general systems, such as the self-organization theory and…
In order to respond to environmental signals, cells often use small molecular circuits to transmit information about their surroundings. Recently, motivated by concrete examples in signaling and gene regulation, a body of work has focused…
For cellular biochemical reaction systems where the numbers of molecules is small, significant noise is associated with chemical reaction events. This molecular noise can give rise to behavior that is very different from the predictions of…
We study the statistical properties of a simple genetic regulatory network that provides heterogeneity within a population of cells. This network consists of a binary genetic switch in which stochastic flipping between the two switch states…
Cells receive signaling molecules by receptors and relay information via sensory networks so that they can respond properly depending on the type of signal. Recent studies have shown that cells can extract multi-dimensional information from…
Directed information transmission is paramount for many social, physical, and biological systems. For neural systems, scientists have studied this problem under the paradigm of feedforward networks for decades. In most models of feedforward…
Identifying the mechanism of intercellular feedback regulation is critical for the basic understanding of tissue growth control in organisms. In this paper, we analyze a tissue growth model consisting of a single lineage of two cell types…
We consider the problem of boundary feedback control of single-input-single-output (SISO) one-dimensional linear hyperbolic systems when sensing and actuation are anti-located. The main issue of the output feedback stabilization is that it…
Fluctuations in biochemical networks, e.g., in a living cell, have a complex origin that precludes a description of such systems in terms of bipartite or multipartite processes, as is usually done in the framework of stochastic and/or…
Living things enact control of non-equilibrium, dynamical structures through complex biochemical networks, accomplishing spatiotemporally-orchestrated physiological tasks such as cell division, motility, and embryogenesis. While the exact…
Signaling in enzymatic networks is typically triggered by environmental fluctuations, resulting in a series of stochastic chemical reactions, leading to corruption of the signal by noise. For example, information flow is initiated by…
Ambient backscatter is an intriguing wireless communication paradigm that allows small devices to compute and communicate by using only the power they harvest from radio-frequency (RF) signals in the air. Ambient backscattering devices…