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Consider a random real tree whose leaf set, or boundary, is endowed with a finite mass measure. Each element of the tree is further given a type, or allele, inherited from the most recent atom of a random point measure…

Probability · Mathematics 2018-09-26 Jean-Jil Duchamps , Amaury Lambert

Kingman's coalescent is a widely used process to model sample genealogies in population genetics. Recently there have been studies on the inference of quantities related to the genealogy of additional individuals given a known sample. This…

Probability · Mathematics 2024-02-29 Linglong Yuan

Consider the Markov process taking values in the partitions of N such that each pair of blocks merges at rate one, and each integer is eroded, i.e., becomes a singleton block, at rate d. This is a special case of exchangeable…

Probability · Mathematics 2019-07-15 Félix Foutel-Rodier , Amaury Lambert , Emmanuel Schertzer

Galled trees are studied as a recombination model in theoretic population genetics. This class of phylogenetic networks has been generalized to tree-child networks, normal networks and tree-based networks by relaxing a structural condition.…

Populations and Evolution · Quantitative Biology 2019-08-05 Louxin Zhang

The goal of these lectures is to review some mathematical aspects of random tree models used in evolutionary biology to model gene trees or species trees. We start with stochastic models of tree shapes (finite trees without edge lengths),…

Probability · Mathematics 2017-08-30 Amaury Lambert

Kingman's coalescent is a random tree that arises from classical population genetic models such as the Moran model. The individuals alive in these models correspond to the leaves in the tree and the following two laws of large numbers…

Probability · Mathematics 2014-06-24 Andrej Depperschmidt , Peter Pfaffelhuber , Annika Scheuringer

We introduce a general diploid population model with self-fertilization and possible overlapping generations, and study the genealogy of a sample of $n$ genes as the population size $N$ tends to infinity. Unlike traditional approach in…

Probability · Mathematics 2026-01-01 Louis Wai-Tong Fan , Maximillian Newman , John Wakeley

Coalescent processes, including mutation, are derived from Moran type population models admitting large offspring numbers. Including mutation in the coalescent process allows for quantifying the turnover of alleles by computing the…

Populations and Evolution · Quantitative Biology 2012-12-11 Bjarki Eldon

We define a doubly infinite, monotone labeling of Bienayme-Galton-Watson (BGW) genealogies. The genealogy of the current generation backwards in time is uniquely determined by the coalescent point process $(A_i; i\ge 1)$, where $A_i$ is the…

Probability · Mathematics 2015-03-17 Amaury Lambert , Lea Popovic

The reconstruction of phylogenetic trees from molecular sequence data relies on modelling site substitutions by a Markov process, or a mixture of such processes. In general, allowing mixed processes can result in different tree topologies…

Populations and Evolution · Quantitative Biology 2016-09-07 Marta Casanellas , Mike Steel

We introduce a colored coalescent process which recovers random colored genealogical trees. Here a colored genealogical tree has its vertices colored black or white. Moving backward along the colored genealogical tree, the color of vertices…

Probability · Mathematics 2007-05-23 Jianjun Tian , Xiao-Song Lin

A topological approach to the study of genetic recombination, based on persistent homology, was introduced by Chan, Carlsson, and Rabad\'an in 2013. This associates a sequence of signatures called barcodes to genomic data sampled from an…

Algebraic Topology · Mathematics 2020-01-17 Michael Lesnick , Raúl Rabadán , Daniel I. S. Rosenbloom

Bertoin and Le Gall (2003) introduced a certain probability measure valued Markov process that describes the evolution of a population, such that a sample from this population would exhibit a genealogy given by the so-called…

Probability · Mathematics 2007-05-23 Andreas Nordvall Lagerås

Take a continuous-time Galton-Watson tree. If the system survives until a large time $T$, then choose $k$ particles uniformly from those alive. What does the ancestral tree drawn out by these $k$ particles look like? Some special cases are…

Probability · Mathematics 2019-02-14 Simon C. Harris , Samuel G. G. Johnston , Matthew I. Roberts

Mounting evidence suggests that natural populations can harbor extensive fitness diversity with numerous genomic loci under selection. It is also known that genealogical trees for populations under selection are quantifiably different from…

Populations and Evolution · Quantitative Biology 2013-01-04 Adel Dayarian , Boris I Shraiman

We calculate the probability distribution of repetitions of ancestors in a genealogical tree for simple neutral models of a closed population with sexual reproduction and non-overlapping generations. Each ancestor at generation g in the…

Condensed Matter · Physics 2009-10-31 B. Derrida , S. C. Manrubia , D. H. Zanette

Under the multispecies coalescent model of molecular evolution, gene trees have independent evolutionary histories within a shared species tree. In comparison, supermatrix concatenation methods assume that gene trees share a single common…

Populations and Evolution · Quantitative Biology 2016-06-13 Huw A. Ogilvie , Joseph Heled , Dong Xie , Alexei J. Drummond

For a genetic locus carrying a strongly beneficial allele which has just fixed in a large population, we study the ancestry at a linked neutral locus. During this ``selective sweep'' the linkage between the two loci is broken up by…

Probability · Mathematics 2007-05-23 Alison Etheridge , Peter Pfaffelhuber , Anton Wakolbinger

Gene trees are evolutionary trees representing the ancestry of genes sampled from multiple populations. Species trees represent populations of individuals -- each with many genes -- splitting into new populations or species. The coalescent…

Populations and Evolution · Quantitative Biology 2010-07-30 Elizabeth S. Allman , James H. Degnan , John A. Rhodes

The multi-species coalescent provides an elegant theoretical framework for estimating species trees and species demographics from genetic markers. Practical applications of the multi-species coalescent model are, however, limited by the…

Populations and Evolution · Quantitative Biology 2011-11-09 David Bryant , Remco Bouckaert , Joseph Felsenstein , Noah Rosenberg , Arindam RoyChoudhury