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Clinical trials usually target average treatment effects, but treatment decisions are made for individuals. This tension motivates a common criticism of evidence-based medicine: a treatment that is beneficial on average may be inappropriate…

Applications · Statistics 2026-05-29 Zach Shahn , Mats Stensrud

Networks provide a mathematically rich framework to represent social contacts sufficient for the transmission of disease. Social networks are often highly clustered and fail to be locally tree-like. In this paper, we study the effects of…

Physics and Society · Physics 2021-06-23 Peter Mann , V. Anne Smith , John B. O. Mitchell , Simon Dobson

Synchronization is of central importance in power distribution, telecommunication, neuronal, and biological networks. Many networks are observed to produce patterns of synchronized clusters, but it has been difficult to predict these…

Interference arises when an individual's potential outcome depends on the individual treatment level, but also on the treatment level of others. A common assumption in the causal inference literature in the presence of interference is…

Methodology · Statistics 2018-05-15 Georgia Papadogeorgou , Fabrizia Mealli , Corwin M. Zigler

Network data have appeared frequently in recent research. For example, in comparing the effects of different types of treatment, network models have been proposed to improve the quality of estimation and hypothesis testing. In this paper,…

Methodology · Statistics 2020-09-04 Zhixin Zhou , Ping Li , Feifang Hu

Interventions are made in networks to change the network or its values in a desired way. The intervention strategies evaluated in the study described here use network sampling designs to find units to which interventions are applied. An…

Methodology · Statistics 2015-11-23 Steven K. Thompson

The progression of chronic diseases often follows highly variable trajectories, and the underlying factors remain poorly understood. Standard mixed-effects models typically represent inter-patient differences as random deviations around a…

We develop randomization-based tests for heterogeneous treatment effects in the presence of network interference. Leveraging the exposure mapping framework, we study a broad class of null hypotheses that represent various forms of constant…

Econometrics · Economics 2025-06-25 Julius Owusu

Inferring causal effects from an observational study is challenging because participants are not randomized to treatment. Observational studies in infectious disease research present the additional challenge that one participant's treatment…

Methodology · Statistics 2020-12-25 Brian G. Barkley , Michael G. Hudgens , John D. Clemens , Mohammad Ali , Michael E. Emch

We consider the problem of identifying infected individuals in a population of size N. We introduce a group testing approach that uses significantly fewer than N tests when infection prevalence is low. The most common approach to group…

Applications · Statistics 2022-01-03 Paolo Bertolotti , Ali Jadbabaie

Motivated by the analysis of social networks, we study a model of random networks that has both a given degree distribution and a tunable clustering coefficient. We consider two types of growth processes on these graphs: diffusion and…

Probability · Mathematics 2012-02-23 Emilie Coupechoux , Marc Lelarge

Understanding spreading dynamics will benefit society as a whole in better preventing and controlling diseases, as well as facilitating the socially responsible information while depressing destructive rumors. In network-based spreading…

Physics and Society · Physics 2015-01-16 Ai-Xiang Cui , Zimo Yang , Tao Zhou

We study spreading on networks where the contact dynamics between the nodes is governed by a random process and where the inter-contact time distribution may differ from the exponential. We consider a process of imperfect spreading, where…

Physics and Society · Physics 2016-07-07 Martin Gueuning , Jean-Charles Delvenne , Renaud Lambiotte

Compartmental models of epidemics are widely used to forecast the effects of communicable diseases such as COVID-19 and to guide policy. Although it has long been known that such processes take place on social networks, the assumption of…

Physics and Society · Physics 2024-03-14 Samuel Johnson

The timing patterns of human communication in social networks is not random. On the contrary, communication is dominated by emergent statistical laws such as non-trivial correlations and clustering. Recently, we found long-term correlations…

Physics and Society · Physics 2014-09-15 Diego Rybski , Sergey V. Buldyrev , Shlomo Havlin , Fredrik Liljeros , Hernan A. Makse

Cluster-level dynamic treatment regimens can be used to guide sequential, intervention or treatment decision-making at the cluster level in order to improve outcomes at the individual or patient-level. In a cluster-level DTR, the…

Methodology · Statistics 2016-07-15 Timothy NeCamp , Amy Kilbourne , Daniel Almirall

When multiple innovations compete for adoption, historical chance leading to early advantage can generate lock-in effects that allow suboptimal innovations to succeed at the expense of superior alternatives. Research on the diffusion of…

Physics and Society · Physics 2023-02-01 Joshua Becker

As the understanding of the importance of social contact networks in the spread of infectious diseases has increased, so has the interest in understanding the feedback process of the disease altering the social network. While many studies…

Physics and Society · Physics 2015-11-03 Lazaros K. Gallos , Nina H. Fefferman

In today's world, individuals interact with each other in more complicated patterns than ever. Some individuals engage through online social networks (e.g., Facebook, Twitter), while some communicate only through conventional ways (e.g.,…

Physics and Society · Physics 2015-09-15 Yong Zhuang , Osman Yağan

In this paper, we propose algorithms that leverage a known community structure to make group testing more efficient. We consider a population organized in disjoint communities: each individual participates in a community, and its infection…

Information Theory · Computer Science 2021-03-18 Pavlos Nikolopoulos , Tao Guo , Sundara Rajan Srinivasavaradhan , Christina Fragouli , Suhas Diggavi