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De novo assembly is the process of reconstructing the genome sequence of an organism from sequencing reads. Genome sequences are essential to biology, and assembly has been a central problem in bioinformatics for four decades. Until…

Genomics · Quantitative Biology 2023-08-16 Heng Li , Richard Durbin

A common theme of data acquisition systems is the transport of data from digitising front-end modules to stable storage and online analysis. A good choice today is to base this on the ubiquitous, commercially and cheaply available Ethernet…

Instrumentation and Detectors · Physics 2020-03-30 H. T. Johansson , A. Furufors , P. Klenze

High-level programming languages play a key role in a growing number of networking platforms, streamlining application development and enabling precise formal reasoning about network behavior. Unfortunately, current compilers only handle…

Programming Languages · Computer Science 2016-11-22 Steffen Smolka , Spiridon Eliopoulos , Nate Foster , Arjun Guha

One-Shot Federated Learning, where a central server learns a global model in a single communication round, has emerged as a promising paradigm. However, under extremely non-IID settings, existing data-free methods often generate low-quality…

Machine Learning · Computer Science 2026-05-12 Li Shen , Xiaolei Hao , Qinglun Li , Xiaochun Cao , Zhifeng Hao , Xun Yang

The growing demand for low-power and area-efficient TinyML inference on AIoT devices necessitates memory architectures that minimise data movement while sustaining high computational efficiency. This paper presents FERMI-ML, a Flexible and…

Hardware Architecture · Computer Science 2026-02-12 Mukul Lokhande , Akash Sankhe , S. V. Jaya Chand , Santosh Kumar Vishvakarma

Background: With the rapid growth of massively parallel sequencing technologies, still more laboratories are utilizing sequenced DNA fragments for genomic analyses. Interpretation of sequencing data is, however, strongly dependent on…

We developed NameMyGene, a web tool and a stand alone program to easily generate putative family-based names for small RNA sequences so that laboratories can easily organize, analyze, and observe patterns from, the massive amount of data…

Cryptography and Security · Computer Science 2012-10-25 Guodong Liu , Zhihua Li , Yuefeng Lin , Bino John

The transformer model has gained widespread adoption in computer vision tasks in recent times. However, due to the quadratic time and memory complexity of self-attention, which is proportional to the number of input tokens, most existing…

Computer Vision and Pattern Recognition · Computer Science 2023-11-13 Wei Tan , Yifeng Geng , Xuansong Xie

Enabling Large Language Models (LLMs) to generate citations in Question-Answering (QA) tasks is an emerging paradigm aimed at enhancing the verifiability of their responses when LLMs are utilizing external references to generate an answer.…

Computation and Language · Computer Science 2024-12-18 Jiajun Shen , Tong Zhou , Yubo Chen , Kang Liu

We introduce HiCat (Hybrid Cell Annotation using Transformative embeddings), a novel semi-supervised pipeline for annotating cell types from single-cell RNA sequencing data. HiCat fuses the strengths of supervised learning for known cell…

Biomolecules · Quantitative Biology 2025-08-21 Chang Bi , Kailun Bai , Xing Li , Xuekui Zhang

As IoT and edge inference proliferate,there is a growing need to simultaneously optimize area and delay in lookup-table (LUT)-based multipliers that implement large numbers of low-bitwidth operations in parallel. This paper proposes a…

Hardware Architecture · Computer Science 2025-10-27 Misaki Kida , Shimpei Sato

Achieving high performance for Sparse MatrixMatrix Multiplication (SpMM) has received increasing research attention, especially on multi-core CPUs, due to the large input data size in applications such as graph neural networks (GNNs). Most…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-12-12 Qiang Fu , Thomas B. Rolinger , H. Howie Huang

Equilibrium reconstruction, which infers internal magnetic fields, plasmas current, and pressure distributions in tokamaks using diagnostic and coil current data, is crucial for controlled magnetic confinement nuclear fusion research.…

We present FlexLLM, a composable High-Level Synthesis (HLS) library for rapid development of domain-specific LLM accelerators. FlexLLM exposes key architectural degrees of freedom for stage-customized inference, enabling hybrid designs that…

Hardware Architecture · Computer Science 2026-01-23 Jiahao Zhang , Zifan He , Nicholas Fraser , Michaela Blott , Yizhou Sun , Jason Cong

In general, there is a mismatch between a finite element model {(FEM)} of a structure and its real behaviour. In aeronautics, this mismatch must be small because {FEM}s are a fundamental part of the development of an aircraft and of…

Computational Engineering, Finance, and Science · Computer Science 2026-04-20 Gabriele Dessena , Alessandro Pontillo , Dmitry I. Ignatyev , James F. Whidborne , Luca Zanotti Fragonara

We propose and implement a comprehensive quantum compilation toolkit for solving the maximum independent set (MIS) problem on quantum hardware based on Rydberg atom arrays. Our end-to-end pipeline involves three core components to…

Predicting equipment anomalies before they escalate into failures is a critical challenge in industrial facility management. Existing approaches rely either on hand-crafted threshold rules, which lack generalizability, or on large neural…

Machine Learning · Computer Science 2026-04-08 Takato Yasuno

Analysis of 1H-NMR spectra is often hindered by large variations that occur during the collection of these spectra. Large solvent and standard peaks, base line drift and negative peaks (due to improper phasing) are among some of these…

Signal Processing · Electrical Eng. & Systems 2020-12-18 Homayoun Valafar , Faramarz Valafar

Mining association rules from data streams is a challenging task due to the (typically) limited resources available vs. the large size of the result. Frequent closed itemsets (FCI) enable an efficient first step, yet current FCI stream…

Databases · Computer Science 2020-07-07 Tomas Martin , Guy Francoeur , Petko Valtchev

Just-In-Time (JIT) defect prediction aims to automatically predict whether a commit is defective or not, and has been widely studied in recent years. In general, most studies can be classified into two categories: 1) simple models using…

Software Engineering · Computer Science 2024-03-19 Xin Zhou , DongGyun Han , David Lo
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