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Inverse protein folding is a fundamental task in computational protein design, which aims to design protein sequences that fold into the desired backbone structures. While the development of machine learning algorithms for this task has…

Machine Learning · Computer Science 2024-11-05 Yiheng Zhu , Jialu Wu , Qiuyi Li , Jiahuan Yan , Mingze Yin , Wei Wu , Mingyang Li , Jieping Ye , Zheng Wang , Jian Wu

Anomaly-based network intrusion detection systems (A-NIDS) use unsupervised models to detect unforeseen attacks. However, existing A-NIDS solutions suffer from low throughput, lack of interpretability, and high maintenance costs. Recent…

Cryptography and Security · Computer Science 2024-04-01 Ruoyu Li , Qing Li , Yu Zhang , Dan Zhao , Xi Xiao , Yong Jiang

Next-generation sequencing technologies have enhanced the scope of Internet-of-Things (IoT) to include genomics for personalized medicine through the increased availability of an abundance of genome data collected from heterogeneous sources…

Significant advances in biotechnology have allowed for simultaneous measurement of molecular data points across multiple genomic and transcriptomic levels from a single tumor/cancer sample. This has motivated systematic approaches to…

Nowadays, online screen sharing and remote cooperation are becoming ubiquitous. However, the screen content may be downsampled and compressed during transmission, while it may be displayed on large screens or the users would zoom in for…

Computer Vision and Pattern Recognition · Computer Science 2022-10-18 Sheng Shen , Huanjing Yue , Jingyu Yang , Kun Li

This study assesses the efficiency of several popular machine learning approaches in the prediction of molecular binding affinity: CatBoost, Graph Attention Neural Network, and Bidirectional Encoder Representations from Transformers. The…

Machine Learning · Computer Science 2020-12-16 Oleksandr Gurbych , Maksym Druchok , Dzvenymyra Yarish , Sofiya Garkot

In the scope of "AI for Science", solving inverse problems is a longstanding challenge in materials and drug discovery, where the goal is to determine the hidden structures given a set of desirable properties. Deep generative models are…

Machine Learning · Computer Science 2022-12-05 Jiaxin Zhang , Sirui Bi , Victor Fung

Summary: Biospectrogam is an open-source software for the spectral analysis of DNA and protein sequences. The software can fetch (from NCBI server), import and manage biological data. One can analyze the data using Digital Signal Processing…

Quantitative Methods · Quantitative Biology 2012-10-05 Naman Turakhia , Nilay Chheda , Manish K. Gupta , Ruchin Shah , Jigar Raisinghani

IR-drop is a critical power integrity challenge in modern VLSI designs that can cause timing degradation, reliability issues, and functional failures if not detected early in the design flow. Conventional IR-drop analysis relies on…

Machine Learning · Computer Science 2026-02-02 Ritesh Bhadana

Natural language processing models tend to learn and encode social biases present in the data. One popular approach for addressing such biases is to eliminate encoded information from the model's representations. However, current methods…

Computation and Language · Computer Science 2023-05-18 Shadi Iskander , Kira Radinsky , Yonatan Belinkov

Glioblastoma (GBM) is an aggressive brain tumor in which IDH mutation status is a key prognostic biomarker, but traditional testing requires invasive biopsies, emphasizing the need for non-invasive approaches. In this multi-center study, we…

This study introduces an innovative crossover operator named Particle Swarm Optimization-inspired Crossover (PSOX), which is specifically developed for real-coded genetic algorithms. Departing from conventional crossover approaches that…

Neural and Evolutionary Computing · Computer Science 2025-05-07 Xiaobo Jin , JiaShu Tu

Software-defined network (SDN) is a new approach that allows network control to become directly programmable, and the underlying infrastructure can be abstracted from applications and network services. Control plane). When it comes to…

Cryptography and Security · Computer Science 2024-11-12 Muhammad Zawad Mahmud , Shahran Rahman Alve , Samiha Islam , Mohammad Monirujjaman Khan

High throughput mRNA expression profiling can be used to characterize the response of cell culture models to perturbations such as pharmacologic modulators and genetic perturbations. As profiling campaigns expand in scope, it is important…

Genomics · Quantitative Biology 2017-04-12 Tracey Filzen , Peter Kutchukian , Jeffrey Hermes , Jing Li , Matthew Tudor

One of the notable fields in studying the genetics of cancer is disease gene identification which affects disease treatment and drug discovery. Many researches have been done in this field. Genome-wide association studies (GWAS) are one of…

Computational Engineering, Finance, and Science · Computer Science 2016-04-27 Zahra Razaghi-Moghadama , Razieh Abdollahia , Sama Goliaeib , Morteza Ebrahimia

Depth completion aims to predict dense depth maps with sparse depth measurements from a depth sensor. Currently, Convolutional Neural Network (CNN) based models are the most popular methods applied to depth completion tasks. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Jian Qian , Miao Sun , Ashley Lee , Jie Li , Shenglong Zhuo , Patrick Yin Chiang

The explanation for deep neural networks has drawn extensive attention in the deep learning community over the past few years. In this work, we study the visual saliency, a.k.a. visual explanation, to interpret convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2022-04-06 Lin Cheng , Pengfei Fang , Yanjie Liang , Liao Zhang , Chunhua Shen , Hanzi Wang

DNA barcodes are crucial in biodiversity analysis for building automatic identification systems that recognize known species and discover unseen species. Unlike human genome modeling, barcode-based invertebrate identification poses…

Machine Learning · Computer Science 2024-12-17 Tiancheng Gao , Graham W. Taylor

A novel interferometric method - SLIVER (Super Localization by Image inVERsion interferometry) - is proposed for estimating the separation of two incoherent point sources with a mean squared error that does not deteriorate as the sources…

Optics · Physics 2016-02-16 Ranjith Nair , Mankei Tsang

As machine learning (ML) systems become increasingly widespread, it is necessary to audit these systems for biases prior to their deployment. Recent research has developed algorithms for effectively identifying intersectional bias in the…

Human-Computer Interaction · Computer Science 2022-06-28 David Munechika , Zijie J. Wang , Jack Reidy , Josh Rubin , Krishna Gade , Krishnaram Kenthapadi , Duen Horng Chau