Related papers: A new paradigm for parallelized STED microscopy
SPAD cameras offer single photon detection sensitivity, high frame rates and zero readout noise. They are a core technology for widefield FLIM, but have further potential in ultra-fast imaging applications. However, in practice sensitivity…
Correlative light and electron microscopy promises to combine molecular specificity with nanoscale imaging resolution. However, there are substantial technical challenges including reliable co-registration of optical and electron images,…
We introduce a novel laser-scanning optical microscopy technique that employs optical-frequency-comb (OFC) lasers. This method facilitates multimodal spectroscopic imaging by analyzing interferograms produced via a dual-comb spectroscopic…
Momentum-resolved scanning transmission electron microscopy (MRSTEM) is a powerful phase-contrast technique that can map lateral magnetic and electric fields ranging from the micrometer to the subatomic scale. Resolving fields ranging from…
We report, for the first time, a multi-confocal Fluorescence Correlation Spectroscopy (mFCS) technique which allows parallel measurements at different locations, by combining a Spatial Light Modulator (SLM), with an Electron Multiplying-CCD…
Simple stencil codes are and remain an important building block in scientific computing. On shared memory nodes, they are traditionally parallelised through colouring or (recursive) tiling. New OpenMP versions alternatively allow users to…
Advancements in fast electron detectors have enabled the statistically significant sampling of crystal structures on the nanometre scale by means of Scanning Electron Nanobeam Diffraction (SEND). Characterisation of structural similarity…
Fast-responding detector arrays are commonly used for imaging rapidly-changing scenes. Besides array detectors, a single-pixel detector combined with a broadband optical spectrum can also be used for rapid imaging by mapping the spectrum…
Sub-diffraction resolution, gentle sample illumination, and the possibility to image in multiple colors make Structured Illumination Microscopy (SIM) an imaging technique which is particularly well suited for live cell observations. Here,…
Replacing electrons with photons is a compelling route towards light-speed, highly parallel, and low-power artificial intelligence computing. Recently, all-optical diffractive neural deep neural networks have been demonstrated. However, the…
We propose the construction of a prototype scanner designed to capture multispectral images of documents. A standard sheet-feed scanner is modified by disconnecting its internal light source and connecting an external multispectral light…
High-speed imaging of cells in flow is essential for probing cellular heterogeneity in large populations. Existing imaging approaches based on single-pixel detection and spatio-temporal encoding provide exceptional speed, but typically rely…
Varifocal lenses, conventionally implemented by changing the axial distance between multiple optical elements, have a wide range of applications in imaging and optical beam scanning. The use of conventional bulky refractive elements makes…
Scanning helium microscopy (SHeM) is an emerging technique that uses a beam of neutral atoms to image and analyse surfaces. The low energies ($\sim$64 meV) and completely non-destructive nature of the probe particles provide exceptional…
I propose a spatial-mode demultiplexing (SPADE) measurement scheme for the far-field imaging of spatially incoherent optical sources. For any object too small to be resolved by direct imaging under the diffraction limit, I show that SPADE…
Two-Photon Laser-Scanning Microscopy is a powerful tool for exploring biological structure and function because of its ability to optically section through a sample with a tight focus. While it is possible to obtain 3D image stacks by…
Metasurfaces provide the disruptive technology enabling miniaturization of complex cascades of optical elements on a plane. We leverage the benefits of such a surface to develop a planar integrated photonic beam collimator for on-chip…
It has been recently demonstrated that integrated optics could enhance accuracy, stability, and ease of use of stellar interferometry techniques. The subject of this thesis is the study of an optical component based on singlemode waveguides…
We introduce the Dichroic-Mirror Camera (DMC), an instrument developed at the University of Tokyo which is capable of performing simultaneous imaging in fifteen bands. The main feature of the DMC is the dichroic mirrors, which split…
Accurate three-dimensional (3D) imaging requires an isotropic point spread function (PSF). However, the inherent missing aperture of a single objective lens results in an elongated, cigar-like PSF, which has rendered isotropic resolution in…