Related papers: Optimized planning target volume margin in helical…
PET/CT imaging is the gold standard for tumor detection, offering high accuracy in identifying local and metastatic lesions. Radiologists often begin assessment with rotational Multi-Angle Maximum Intensity Projections (MIPs) from PET,…
Radiation therapy is an important tool in the treatment of breast cancer and can play a crucial role in improving patient outcomes. For breast cancer, if the technique has been for a long time the use of 3DCRT, clinicians have seen the…
Purpose: To describe the dosimetric commissioning and quality assurance (QA) of the actively scanned proton and carbon ion beams at the Italian National Center for Oncological Hadrontherapy. Methods: The laterally integrated…
Purpose: Demonstrate quantitative characterization of 3D patient-specific absorbed dose distributions using Haralick texture analysis and interpret measures in terms of underlying physics and radiation dosimetry. Methods: Retrospective…
Protoacoustic imaging showed great promise in providing real-time 3D dose verification of proton therapy. However, the limited acquisition angle in protoacoustic imaging induces severe artifacts, which significantly impairs its accuracy for…
High-dose-rate (HDR) brachytherapy plays a critical role in the treatment of locally advanced cervical cancer but remains highly dependent on manual treatment planning expertise. The objective of this study is to develop a fully automated…
As intensities of MRI volumes are inconsistent across institutes, it is essential to extract universal features of multi-modal MRIs to precisely segment brain tumors. In this concept, we propose a volumetric vision transformer that follows…
We demonstrate the application of mixture density networks (MDNs) in the context of automated radiation therapy treatment planning. It is shown that an MDN can produce good predictions of dose distributions as well as reflect uncertain…
The purpose of our study is to develop a new, 3-dimensional dosimetry system to verify the accuracy of dose deliveries in Leksell Gamma Knife-Perfexion TM (LGKP) (Elekta, Norcross, GA, USA). The instrument consists of a moving head phantom,…
Prognostic tumor growth modeling via volumetric medical imaging observations can potentially lead to better outcomes of tumor treatment and surgical planning. Recent advances of convolutional networks have demonstrated higher accuracy than…
Adaptive radiotherapy is a growing field of study in cancer treatment due to it's objective in sparing healthy tissue. The standard of care in several institutions includes longitudinal cone-beam computed tomography (CBCT) acquisitions to…
Treatment planning is currently a patient specific, time-consuming, and resource demanding task in radiotherapy. Dose-volume histogram (DVH) prediction plays a critical role in automating this process. The geometric relationship between…
In this study we performed a feasibility investigation on implementing a fast and accurate dose calculation based on a deep learning technique. A two dimensional (2D) fluence map was first converted into a three dimensional (3D) volume…
Imaging demonstrates that preclinical and human tumors are heterogeneous, i.e. a single tumor can exhibit multiple regions that behave differently during both normal development and also in response to treatment. The large variations…
Background: Intensity-modulated proton therapy (IMPT) using pencil beam technique scans tumor in a layer by layer, then spot by spot manner. It can provide highly conformal dose to tumor targets and spare nearby organs-at-risk (OAR). Fast…
Background: The deep inspiration breath hold technique (DIBH) is widely used for left-sided breast radiotherapy (RT), in order to reduce the dose to the heart and the risk of cardiotoxicity. The volumetric arc therapy (VMAT) technique…
In this paper, we would like to quantitatively measure the tumor volume contained in the breast imaged by the Digital Breast Tomosynthesis (DBT), a reconstructed 3D image. The estimated volume will add to the prognostic value of risk…
Malignant and benign breast tumors present differently in their shape and size on sonography. Morphological information provided by tumor contours are important in clinical diagnosis. However, ultrasound images contain noises and tissue…
The treatment of breast cancer using radiotherapy involves uncertainties regarding breast positioning. As the studies progress, more is known about the expected breast positioning errors, which are taken into account in the Planning Target…
Purpose: A promising approach to enable FLASH conformal proton therapy is to passively degrade a single energy layer using a patient-specific range modulator. We propose an innovative method to directly optimize the geometrical…