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The cellular cytoskeleton is an active material, driven out of equilibrium by molecular motor proteins. It is not understood how the collective behaviors of cytoskeletal networks emerge from the properties of the network's constituent motor…

Subcellular Processes · Quantitative Biology 2017-12-19 Peter J. Foster , Wen Yan , Sebastian Fürthauer , Michael J. Shelley , Daniel J. Needleman

Accurately modeling contact behaviors for real-world, near-rigid materials remains a grand challenge for existing rigid-body physics simulators. This paper introduces a data-augmented contact model that incorporates analytical solutions…

Robotics · Computer Science 2022-06-23 Yifeng Jiang , Jiazheng Sun , C. Karen Liu

Guided by recent advances in the understanding of nucleation and propagation of fracture in elastic brittle materials, this paper proposes a suite of three simple experiments that permit the measurement of the three macroscopic material…

Soft Condensed Matter · Physics 2026-05-13 Subhrangsu Saha , Bruce J. Moore , Ben Manaugh , Jeffery R. Roesler , Oscar Lopez-Pamies

A continuum description is built to characterize the stationary and transient deformations of confluent tissues subject to heterogeneous activities. By defining a coarse-grained texture matrix field to represent the shape and size of cells,…

Biological Physics · Physics 2023-08-10 Fernanda Pérez-Verdugo , Rodrigo Soto

The Dynamic Template is applied to muscle cells, and is shown to provide a feedback mechanism that can co-ordinate the rearrangements of cytoskeletal proteins that accompany contraction

General Physics · Physics 2008-07-15 J. T. Lofthouse

Experimental testing on dry woven fabrics exhibits a complex set of evidences that are difficult to be completely described using classical continuum models. The aim of this paper is to show how the introduction of energy terms related to…

Soft Condensed Matter · Physics 2016-09-16 Gabriele Barbagallo , Angela Madeo , Fabrice Morestin , Philippe Boisse

The native structures of proteins, except for notable exceptions of intrinsically disordered proteins, in general take their most stable conformation in the physiological condition to maintain their structural framework so that their…

Biomolecules · Quantitative Biology 2021-10-26 Lyman Monroe , Daisuke Kihara

Soft elastic filaments that can be stretched, bent and twisted exhibit a range of topologically and geometrically complex morphologies that include plectonemes, solenoids, knot-like and braid-like structures. We combine numerical…

Soft Condensed Matter · Physics 2019-11-20 Nicholas Charles , Mattia Gazzola , L. Mahadevan

Proteins constitute a large group of macromolecules with a multitude of functions for all living organisms. Proteins achieve this by adopting distinct three-dimensional structures encoded by the sequence of their constituent amino acids in…

Methodology · Statistics 2021-09-16 Mohammad Arashi , Najmeh Nakhaei Rad , Andriette Bekker , Wolf Dieter Schubert

Constitutive models that describe the mechanical behavior of soft tissues have advanced greatly over the past few decades. These expert models are generalizable and require the calibration of a number of parameters to fit experimental data.…

Quantitative Methods · Quantitative Biology 2021-07-13 Vahidullah Tac , Vivek D. Sree , Manuel K. Rausch , Adrian B. Tepole

The increasing number of protein-based metamaterials demands reliable and efficient theoretical and computational methods to study the physicochemical properties they may display. In this regard, we develop a simulation strategy based on…

Soft Condensed Matter · Physics 2020-06-23 J. A. Campos Gonzalez Angulo , G. Wiesehan , R. F. Ribeiro , J. Yuen-Zhou

The complex ways in which humans utilize their bodies in sports and martial arts are remarkable, and human motion analysis is one of the most effective tools for robot body design and control. On the other hand, motion analysis is not easy,…

Skeletal muscle modeling has a vital role in movement studies and the development of therapeutic approaches. In the current study, a Huxley-based model for skeletal muscle is proposed, which demonstrates the impact of impairments in muscle…

Medical Physics · Physics 2023-09-07 Fatemeh Jalali , Mohammad Ali Nazari , Arash Bahrami , Pascal Perrier , Yohan Payan

The latest advances in computer-assisted precision medicine are making it feasible to move from population-wide models that are useful to discover aggregate patterns that hold for group-based analysis to patient-specific models that can…

Computer Vision and Pattern Recognition · Computer Science 2021-07-28 Da Ma , Vincent Chow , Karteek Popuri , Mirza Faisal Beg

In this paper, we introduce tensor involved peridynamics, a unified framework for simulating both isotropic and anisotropic materials. While traditional peridynamics models effectively simulate isotropic materials, they face challenges with…

Materials Science · Physics 2024-12-23 Hao Tian , Jinlong Shao , Chenguang Liu , Shuo Liu , Xu Guo

Application of soft and compliant joints in grasping mechanisms received an increasing attention during recent years. This article suggests the design and development of a novel bio-inspired compliant finger which is composed of a 3D…

Robotics · Computer Science 2023-04-14 Mahmoud Tavakoli , Andriy Sayuk , João Lourenço , Pedro Neto

Assessing the structural properties of large proteins is important to gain an understanding of their function in, e.g., biological systems or biomedical applications. We propose a method to examine the mechanical properties of proteins…

Living soft tissues appear to promote the development and maintenance of a preferred mechanical state within a defined tolerance around a so-called set-point. This phenomenon is often referred to as mechanical homeostasis. In contradiction…

Computational Engineering, Finance, and Science · Computer Science 2021-09-23 Jonas F. Eichinger , Maximilian J. Grill , Iman Davoodi Kermani , Roland C. Aydin , Wolfgang A. Wall , Jay D. Humphrey , Christian J. Cyron

Assessing the progression of muscle fatigue for daily exercises provides vital indicators for precise rehabilitation, personalized training dose, especially under the context of Metaverse. Assessing fatigue of multi-muscle…

Human-Computer Interaction · Computer Science 2024-12-03 Chunzhi Yi , Xiaolei Sun , Chunyu Zhang , Wei Jin , Jianfei Zhu , Haiqi Zhu , Baichun Wei

The Young's modulus of a two-dimensional truss-like structure is simulated by using the finite element method. A power-law expression is proposed for the effective Young's modulus of the system. The obtained numerical results are compared…

Soft Condensed Matter · Physics 2007-05-23 Enis Tuncer , Michael Wegener
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