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Related papers: Structural Changes of Active Skeletal Muscles: Mod…

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In Part I of this article we have developed a novel mechanobiological model of a Tissue Engineering process that accounts for the mechanisms through which an isotropic or anisotropic adherence condition regulates the active functions of the…

Numerical Analysis · Mathematics 2015-12-14 Chiara Lelli , Riccardo Sacco , Paola Causin , Manuela T. Raimondi

Segmenting muscle compartments and measuring their architecture can facilitate movement function assessment, accurate musculoskeletal modeling, and synergy-based electromyogram simulation. Here, we presented a novel method for volumetric…

Image and Video Processing · Electrical Eng. & Systems 2025-07-02 Yang Li

Lower limb amputees often suffer skin and tissue problems from using their prosthesis which is a challenging biomechanical problem. The finite element method (FEM) has previously been applied to analyse internal mechanical conditions of the…

Medical Physics · Physics 2019-08-02 Sara Kallin , Asim Rashid , Kent Salomonsson , Peter Hansbo

Objective: To test automated in vivo estimation of active and passive skeletal muscle states using ultrasonic imaging. Background: Current technology (electromyography, dynamometry, shear wave imaging) provides no general, non-invasive…

Image and Video Processing · Electrical Eng. & Systems 2019-07-04 Ryan J. Cunningham , Ian D. Loram

We present a continuum model for the mechanical behavior of the skeletal muscle tissue when its functionality is reduced due to aging. The loss of ability of activating is typical of the geriatric syndrome called sarcopenia. The material is…

Tissues and Organs · Quantitative Biology 2018-05-03 Giulia Giantesio , Alessandro Musesti

The initiation of directional cell motion requires symmetry breaking that can happen both with or without external stimuli. During cell crawling, forces generated by the cytoskeleton and their transmission through mechanosensitive adhesions…

Cell Behavior · Quantitative Biology 2023-06-02 Yuzhu Chen , David Saintillan , Padmini Rangamani

There is compelling evidence that substrate stiffness affects cell adhesion as well as cytoskeleton organization and contractile activity. This work was designed to study the cytoskeletal contractile activity of cells plated on microposts…

Cell Behavior · Quantitative Biology 2019-09-13 Ian Manifacier , Kevin Beussman , Sangyoon Han , Nathan Sniadecki , Imad About , Jean-Louis Milan

Contractile forces exerted on the surrounding extracellular matrix (ECM) lead to the alignment and stretching of constituent fibers within the vicinity of cells. As a consequence, the matrix reorganizes to form thick bundles of aligned…

Cell Behavior · Quantitative Biology 2014-09-23 Abhilash Nair , Brendon M. Baker , Britta Trappmann , Christopher S. Chen , Vivek B. Shenoy

Collagen fibrils are the most important structural component of tendons. Their crimped structure and parallel arrangement within the tendon lead to a distinctive non-linear stress-strain curve when a tendon is stretched. Microstructural…

Tissues and Organs · Quantitative Biology 2021-03-09 James Gregory , Tom Shearer , Andrew L. Hazel

Skeletal muscles are organized into distinct layers and exhibit anisotropic characteristics across various scales. Assessing the arrangement of skeletal muscles may provide valuable biomarkers for diagnosing muscle related pathologies and…

The influence of the microstructural geometry on the behavior of porous media is widely recognized, particularly in geomaterials, but also in biomaterials and engineered materials. Recent advances in imaging techniques, such as X-ray…

Soft Condensed Matter · Physics 2021-07-01 Alexandre Guével , Hadrien Rattez , Manolis Veveakis

During growth, tissue expands and deforms. Given its elastic properties, stresses emerge in an expanding and deforming tissue. Cell rearrangements can dissipate these stresses and numerous experiments confirm the viscoelastic properties of…

Tissues and Organs · Quantitative Biology 2017-10-20 M. D. Peters , D. Iber

State of the art research and treatment of biological tissues require accurate and efficient methods for describing their mechanical properties. Indeed, micromechanics motivated approaches provide a systematic method for elevating relevant…

Soft Condensed Matter · Physics 2012-05-04 Gal deBotton , Tal Oren

Wood as the most important natural and renewable building material plays an important role in the construction sector. Nevertheless, its hygroscopic character basically affects all related mechanical properties leading to degradation of…

Soft Condensed Matter · Physics 2014-11-06 Mohammad Masoud Hassani , Falk K. Wittel , Stefan Hering , Hans J. Herrmann

The cytoskeleton is a model active matter system that controls diverse cellular processes from division to motility. While both active actomyosin dynamics and actin-microtubule interactions are key to the cytoskeleton's versatility and…

This paper presents a new approach to study the effects of temperature on the poro- elastic and viscoelastic behavior of articular cartilage. Biphasic solid-fluid mixture theory is applied to study the poro-mechancial behavior of articular…

Biological Physics · Physics 2017-10-17 Reza Behrou , Hamid Foroughi , Fardad Haghpanah

We present a methodology to simulate the mechanics of knots in elastic rods using geometrically nonlinear, full three-dimensional (3D) finite element analysis. We focus on the mechanical behavior of knots in tight configurations, for which…

Soft Condensed Matter · Physics 2021-02-03 Changyeob Baek , Paul Johanns , Tomohiko G. Sano , Paul Grandgeorge , Pedro M. Reis

Living cells are soft bodies of a characteristic form, but endowed with a capacity for a steady turnover of their structures. Both of these material properties, i.e. recovery of the shape after an external stress has been imposed and…

Soft Condensed Matter · Physics 2007-05-23 Erwin Frey , Klaus Kroy , Jan Wilhelm

Recent biological experiments have shown that certain types of cells are able to move in structured and confined environment even without the activation of focal adhesion. Focusing on this particular phenomenon and based on previous works,…

Analysis of PDEs · Mathematics 2022-12-05 Chiara Giverso , Gaspard Jankowiak , Luigi Preziosi , Christian Schmeiser

Changes in the mechanical properties of granular materials, induced by variations in the intrinsic compressibility of the particles, are investigated by means of numerical simulations based on the combination of the Finite Element and…

Soft Condensed Matter · Physics 2020-12-02 Thi-Lo Vu , Saeid Nezamabadi , Serge Mora