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Related papers: Towards wide-field high-resolution retinal imaging

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Illuminating or imaging samples from a broad angular range is essential in a wide variety of computational 3D imaging and resolution-enhancement techniques, such as optical projection tomography (OPT), optical diffraction tomography (ODT),…

High-resolution optical imaging methods, such as confocal microscopy and full-field optical coherence tomography, capture flat optical sections of the sample. If the sample is curved, the optical field sections through several sample layers…

Medical Physics · Physics 2020-07-31 Viacheslav Mazlin , Kristina Irsch , Michel Paques , Mathias Fink , Albert Claude Boccara

Multi-Conjugate Adaptive Optics (MCAO) combines the advantages of standard adaptive optics, which provides high contrast and high spatial resolution, and of wide field ~1' imaging. Up to recently, MCAO for astronomy was limited to…

Astrophysics · Physics 2009-11-13 H. Bouy , J. Kolb , E. Marchetti , E. L. Martin , N. Huelamo , D. Barrado y Navascues

Effective and accurate in-vivo diagnosis of retinal pathologies requires high performance imaging devices, combining a large field of view and the ability to discriminate the ballistic signal from the diffuse background in order to provide…

Light from astronomical objects must travel through the earth's turbulent atmosphere before it can be imaged by ground-based telescopes. To enable direct imaging at maximum theoretical angular resolution, advanced techniques such as those…

Adaptive optics (AO) is a powerful image correction technique with proven benefits for many life-science microscopy methods. However, the complexity of adding a reflective wavefront modulator and a wavefront sensor into already complicated…

Multi-photon microscopy is a powerful technique for deep-tissue imaging, providing high spatial resolution at increased penetration depth. Nevertheless, imaging remains largely restricted to superficial tissue layers well below 1 mm.…

The imaging performance of an optical microscope can be degraded by sample-induced aberrations. A general strategy to undo the effect of these aberrations is to apply wavefront correction with a deformable mirror (DM). In most cases, the DM…

Optics · Physics 2015-06-23 Jerome Mertz , Hari Paudel , Thomas G. Bifano

Aberrations limit scanning fluorescence microscopy when imaging in scattering materials such as biological tissue. Model-based approaches for adaptive optics take advantage of a computational model of the optical setup. Such models can be…

Optics · Physics 2021-07-07 Ivan Vishniakou , Johannes D. Seelig

In this work, we propose a new paradigm of iterative model-based reconstruction algorithms for providing real-time solution for zooming-in and refining a region of interest in medical and clinical tomographic images. This algorithmic…

Image and Video Processing · Electrical Eng. & Systems 2025-12-01 Junqi Tang , Guixian Xu , Jinglai Li

The optical resolution of a digital camera is one of its most crucial parameters with broad relevance for consumer electronics, surveillance systems, remote sensing, or medical imaging. However, resolution is physically limited by the…

Computer Vision and Pattern Recognition · Computer Science 2018-12-27 Thomas Köhler

In optical imaging, light propagation is affected by the inhomogeneities of the medium. Sample-induced aberrations and multiple scattering can strongly degrade the image resolution and contrast. Based on a dynamic correction of the incident…

Adaptive optics (AO) is a powerful tool employed across various research fields, from aerospace to microscopy. Traditionally, AO has focused on correcting optical phase aberrations, with recent advances extending to polarisation…

Multi-conjugated adaptive optics (MCAO) yield nearly diffraction-limited images at 2$\mu$m wavelengths. Currently, GeMS/GSAOI at Gemini South is the only MCAO facility instrument at an 8m telescope. Using real data and for the first time,…

Instrumentation and Methods for Astrophysics · Physics 2017-09-08 Mischa Schirmer , Vincent Garrel , Gaetano Sivo , Eduardo Marin , Eleazar R. Carrasco

Imaging through complex scattering media is severely limited by aberrations and scattering which obscure images and reduce resolution. Confocal and temporal gatings partly filter out multiple scattering but are severely degraded by…

Optics · Physics 2026-05-18 Yiwen Zhang , Minh Dinh , Zeyu Wang , Tianhao Zhang , Tianhang Chen , Chia Wei Hsu

Adaptive optics (AO) corrected ood imaging of the retina is a popular technique for studying the retinal structure and function in the living eye. However, the raw retinal images are usually of poor contrast and the interpretation of such…

Optimization and Control · Mathematics 2020-12-30 Xiaotong Chen , James L. Herring , James G. Nagy , Yuanzhe Xi , Bo Yu

Multidimensional imaging, capturing image data in more than two dimensions, has been an emerging field with diverse applications. Due to the limitation of two-dimensional detectors in obtaining the high-dimensional image data, computational…

Image and Video Processing · Electrical Eng. & Systems 2020-06-16 Didem Dogan , Figen S. Oktem

Accurate detection and segmentation of cone cells in the retina are essential for diagnosing and managing retinal diseases. In this study, we used advanced imaging techniques, including confocal and non-confocal split detector images from…

Image and Video Processing · Electrical Eng. & Systems 2024-10-22 Prajol Shrestha , Mikhail Kulyabin , Aline Sindel , Hilde R. Pedersen , Stuart Gilson , Rigmor Baraas , Andreas Maier

A ground-layer adaptive optics system (GLAO) uses a single adaptive mirror to partially correct the wavefront for atmospheric and telescope aberrations over a wide field of view. Instead of reaching diffraction limit on a narrow field, the…

Instrumentation and Methods for Astrophysics · Physics 2017-06-02 Donald Gavel

It is widely believed that adaptive optics only has a role in correcting turbulent wavefronts on large telescopes using very bright reference stars. Unfortunately these are very scarce and many astronomical targets require wavefront…

Instrumentation and Methods for Astrophysics · Physics 2019-11-19 Craig Mackay