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In this study, the absorbed dose calculation for the cerebral region is refined using the Geant4 software, along with the ROOT and GATE programs. This approach provides a detailed statistical analysis of positron trajectories within a water…

Medical Physics · Physics 2025-05-06 Walter Sabalza-Castillejo , Miguel Martin-Landrove

Purpose: The presence of respiratory motion during radiation treatment leads to degradation of the expected dose distribution, both for target coverage and healthy-tissue sparing, particularly for techniques like pencil-beam scanning proton…

In this paper we investigate, with a detailed Monte-Carlo simulation based on Geant4, the novel approach [Nucl. Instrum. Methods A588 (2008) 457] to 3D imaging with photon scattering. A monochromatic and well collimated gamma beam is used…

Medical Physics · Physics 2011-09-23 M. Lenti , M. Veltri

The Fast Dose Calculator (FDC), a track repeating algorithm Monte Carlo method was initially developed for proton therapy. The validation for proton therapy has been demonstrated in a previous work. This method can be expanded to ion…

Medical Physics · Physics 2018-09-18 Qianxia Wang , Antony Adair , Yu Deng , Hongliang Chen , M Moyers , James Lin , Pablo Yepes

A proton pencil beam is associated with a surrounding low-dose envelope, originating from nuclear interactions. It is important for treatment planning systems to accurately model this envelope when performing dose calculations for pencil…

Medical Physics · Physics 2015-11-30 David C. Hall , Anastasia Makarova , Harald Paganetti , Bernard Gottschalk

Monte Carlo simulation is the most accurate method for absorbed dose calculations in radiotherapy. Its efficiency still requires improvement for routine clinical applications, especially for online adaptive radiotherapy. In this paper, we…

Medical Physics · Physics 2015-05-14 Xun Jia , Xuejun Gu , Josep Sempau , Dongju Choi , Amitava Majumdar , Steve B. Jiang

Cloud computing allows for vast computational resources to be leveraged quickly and easily in bursts as and when required. Using the Amazon Elastic Compute Cloud and the Amazon Simple Storage Solution, we describe a technique that allows…

Medical Physics · Physics 2011-05-10 Christopher M Poole , Iwan Cornelius , Jamie V Trapp , Christian M Langton

Monte Carlo (MC) simulation is commonly considered to be the most accurate dose calculation method in radiotherapy. However, its efficiency still requires improvement for many routine clinical applications. In this paper, we present our…

Medical Physics · Physics 2015-05-28 Xun Jia , Xuejun Gu , Yan Jiang Graves , Michael Folkerts , Steve B. Jiang

The XCAT phantom is a realistic 4D digital torso phantom that is widely used in imaging and therapy research. However, lung mass is not conserved between respiratory phases of the phantom, making detailed dosimetric simulations and dose…

This paper describes the development and validation of a Monte Carlo (MC) dose computing module dedicated to organ dose calculations of patients undergoing nuclear medicine (NM) internal radiation exposures involving 18F-FDG PET/CT…

Medical Physics · Physics 2022-03-30 Zhao Peng , Yu Lu , Yao Xu , Yongzhe Li , Bo Cheng , Ming Ni , Zhi Chen , Xi Pei , Qiang Xie , Shicun Wang , X. George Xu

Purpose: Monte Carlo methods are considered the gold standard for dosimetric computations in radiotherapy. Their execution time is however still an obstacle to the routine use of Monte Carlo packages in a clinical setting. To address this…

Medical Physics · Physics 2015-03-17 Sami Hissoiny , Hugo Bouchard , Benoît Ozell , Philippe Després

Purpose: This paper describes a new method to apply deep-learning algorithms for automatic segmentation of radiosensitive organs from 3D tomographic CT images before computing organ doses using a GPU-based Monte Carlo code. Methods: A deep…

Medical Physics · Physics 2020-09-09 Zhao Peng , Xi Fang , Pingkun Yan , Hongming Shan , Tianyu Liu , Xi Pei , Ge Wang , Bob Liu , Mannudeep K. Kalra , X. George Xu

Monte Carlo (MC) methods provide the most accurate to-date dose calculations in heterogeneous media and complex geometries, and this spawns increasing interest in incorporating MC calculations into treatment planning quality assurance…

Medical Physics · Physics 2009-01-07 C. Locke , S. Zavgorodni

Purpose: To develop a Monte Carlo (MC) therapeutic dose calculation toolkit of a recently released ring gantry linac in Geant4 (Version 10.7) for secondary dose validation of radiotherapy plan. Methods: For the Halcyon (Varian Medical…

Medical Physics · Physics 2022-10-04 Ruirui Liu , Zhen Ji , Xiandong Zhao , Tianyu Zhao , Abhishek Sethi , Daren Sawkey , Bin Cai

Monte Carlo calculations using the codes PENELOPE and GEANT4 have been performed to characterize the dosimetric properties of monoenergetic photon point sources in water. The dose rate in water has been calculated for energies of interest…

Medical Physics · Physics 2015-06-26 Julio F. Almansa , Rafael Guerrero , Feras M. O. Al-Dweri , M. Anguiano , A. M. Lallena

A Geant4 based simulation tool has been developed to perform Monte Carlo modelling of a 6 MV VarianTM iX clinac. The computer aided design interface of Geant4 was used to accurately model the LINAC components, including the Millenium…

The Miniaturized Detector for Application in Space (MIDAS) is a compact device with dimensions 5 x 5 x 1 cm3 which combines position sensitive Si detectors and a fast neutrons spectrometer. MIDAS is developed with purpose to act as a linear…

Instrumentation and Detectors · Physics 2022-02-22 K. Karafasoulis , C. Papadimitropoulos , C. Potiriadis , C. P. Lambropoulos

Cone beam CT (CBCT) has been widely used for patient setup in image guided radiation therapy (IGRT). Radiation dose from CBCT scans has become a clinical concern. The purposes of this study are 1) to commission a GPU-based Monte Carlo (MC)…

Skin dose in radiotherapy is a key issue for reducing patient side effects, but dose calculations in this high-gradient region remains a challenge. To support radiation therapists and medical physicist in their decisions, a computational…

A set of physics models for nanodosimetry simulation is being re-engineered for use in Geant4-based simulations. This extension of Geant4 capabilities is part of a larger scale R&D project for multi-scale simulation involving adaptable,…

Computational Physics · Physics 2009-12-10 E. Gargioni , V. Grichine , M. G. Pia
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