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Advances in genome sequencing technologies generate massive amounts of sequence data that are increasingly analyzed and shared through public repositories. On-demand infrastructure services on cloud computing platforms enable the processing…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-20 Junseok Park , Eduardo A. Maury , Changhoon Oh , Donghoon Shin , Danielle Denisko , Eunjung Alice Lee

Since the advent of next-generation sequencing in the early 2000s, the volume of bioinformatics software tools and databases has exploded and continues to grow rapidly. Documenting this evolution on a global and time-dependent scale is a…

This paper presents the Container Profiler, a software tool that measures and records the resource usage of any containerized task. Our tool profiles the CPU, memory, disk, and network utilization of containerized tasks collecting over…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-02-08 Varik Hoang , Ling-Hong Hung , David Perez , Huazeng Deng , Raymond Schooley , Niharika Arumilli , Ka Yee Yeung , Wes Lloyd

The growing demand for real-time processing tasks is driving the need for multi-model inference pipelines on edge devices. However, cost-effectively deploying these pipelines while optimizing Quality of Service (QoS) and costs poses…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-05 Jinhao Sheng , Zhiqing Tang , Jianxiong Guo , Tian Wang

Quantum network simulators offer the opportunity to cost-efficiently investigate potential avenues to building networks that scale with the number of users, communication distance, and application demands by simulating alternative hardware…

Quantum Physics · Physics 2024-08-13 Xiaoliang Wu , Alexander Kolar , Joaquin Chung , Dong Jin , Rajkumar Kettimuthu , Martin Suchara

This article presents an automatic approach to quickly derive a good solution for hardware resource partition and task granularity for task-based parallel applications on heterogeneous many-core architectures. Our approach employs a…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-03-10 Peng Zhang , Jianbin Fang , Canqun Yang , Chun Huang , Tao Tang , Zheng Wang

Maximizing the computational utility of near-term quantum processors requires predictive noise models that inform robust, noise-aware compilation and error mitigation. Conventional models often fail to capture the complex error dynamics of…

Quantum Physics · Physics 2026-03-17 Yanjun Ji , Marco Roth , David A. Kreplin , Ilia Polian , Frank K. Wilhelm

Computational intensity and sequential nature of estimation techniques for Bayesian methods in statistics and machine learning, combined with their increasing applications for big data analytics, necessitate both the identification of…

Computation · Statistics 2015-03-02 Alireza S. Mahani , Mansour T. A. Sharabiani

In this paper, we present PARTIME, a software library written in Python and based on PyTorch, designed specifically to speed up neural networks whenever data is continuously streamed over time, for both learning and inference. Existing…

Machine Learning · Computer Science 2022-12-05 Enrico Meloni , Lapo Faggi , Simone Marullo , Alessandro Betti , Matteo Tiezzi , Marco Gori , Stefano Melacci

Computational analysis methods including machine learning have a significant impact in the fields of genomics and medicine. High-throughput gene expression analysis methods such as microarray technology and RNA sequencing produce enormous…

Genomics · Quantitative Biology 2022-09-28 Nikita Bhandari , Rahee Walambe , Ketan Kotecha , Satyajeet Khare

RNA-sequencing (RNA-seq) has become an exemplar technology in modern biology and clinical applications over the past decade. It has gained immense popularity in the recent years driven by continuous efforts of the bioinformatics community…

Accurately estimating workload runtime is a longstanding goal in computer systems, and plays a key role in efficient resource provisioning, latency minimization, and various other system management tasks. Runtime prediction is particularly…

Machine Learning · Computer Science 2025-03-11 Tianshu Huang , Arjun Ramesh , Emily Ruppel , Nuno Pereira , Anthony Rowe , Carlee Joe-Wong

Motivation: Statistical analysis of microbial count data derived from 16S rRNA or metagenomics sequencing poses unique challenges due to the sparse, compositional, and high-dimensional nature of the data. While QIIME 2 already provides many…

Quantitative Methods · Quantitative Biology 2026-04-20 Oleg Vlasovets , Fabian Schaipp , Leo Simpson , Evan Bolyen , J. Gregory Caporaso , Christian L. Mueller

Applying machine learning to biological sequences - DNA, RNA and protein - has enormous potential to advance human health, environmental sustainability, and fundamental biological understanding. However, many existing machine learning…

Machine Learning · Statistics 2023-04-11 Alan Nawzad Amin , Eli Nathan Weinstein , Debora Susan Marks

High throughput genome sequencing technologies such as RNA-Seq and Microarray have the potential to transform clinical decision making and biomedical research by enabling high-throughput measurements of the genome at a granular level.…

Next-generation RNA sequencing (RNA-seq) technology has been widely used to assess full-length RNA isoform abundance in a high-throughput manner. RNA-seq data offer insight into gene expression levels and transcriptome structures, enabling…

Applications · Statistics 2021-12-01 Wei Vivian Li , Anqi Zhao , Shihua Zhang , Jingyi Jessica Li

Quantum Machine Learning (QML) continues to evolve, unlocking new opportunities for diverse applications. In this study, we investigate and evaluate the applicability of QML models for binary classification of genome sequence data by…

Machine Learning · Computer Science 2025-01-15 Navneet Singh , Shiva Raj Pokhrel

Quantum neural networks hold significant promise for numerous applications, particularly as they can be executed on the current generation of quantum hardware. However, due to limited qubits or hardware noise, conducting large-scale…

In biological research machine learning algorithms are part of nearly every analytical process. They are used to identify new insights into biological phenomena, interpret data, provide molecular diagnosis for diseases and develop…

Predictive business process monitoring methods exploit logs of completed cases of a process in order to make predictions about running cases thereof. Existing methods in this space are tailor-made for specific prediction tasks. Moreover,…

Applications · Statistics 2017-12-20 Niek Tax , Ilya Verenich , Marcello La Rosa , Marlon Dumas