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Group testing is a well known search problem that consists in detecting up to $s$ defective elements of the set $[t]=\{1,\ldots,t\}$ by carrying out tests on properly chosen subsets of $[t]$. In classical group testing the goal is to find…

Information Theory · Computer Science 2016-07-05 A. G. D'yachkov , I. V. Vorobyev , N. A. Polyanskii , V. Yu. Shchukin

Drug discovery (DD) has tremendously contributed to maintaining and improving public health. Hypothesizing that inhibiting protein misfolding can slow disease progression, researchers focus on target identification (Target ID) to find…

Quantitative Methods · Quantitative Biology 2025-01-29 Ziwen Li , Xiang 'Anthony' Chen , Youngseung Jeon

In this paper we study a new, generalized version of the well-known group testing problem. In the classical model of group testing we are given n objects, some of which are considered to be defective. We can test certain subsets of the…

Combinatorics · Mathematics 2012-04-09 Dániel Gerbner , Balázs Keszegh , Dömötör Pálvölgyi , Gábor Wiener

Group testing is a well known search problem that consists in detecting up to $s$ defective elements of the set $[t]=\{1,\ldots,t\}$ by carrying out tests on properly chosen subsets of $[t]$. In classical group testing the goal is to find…

Information Theory · Computer Science 2016-11-18 A. G. D'yachkov , I. V. Vorobyev , N. A. Polyanskii , V. Yu. Shchukin

Group testing enables to identify infected individuals in a population using a smaller number of tests than individual testing. To achieve this, group testing algorithms commonly assume knowledge of the number of infected individuals;…

Information Theory · Computer Science 2023-05-16 Chaorui Yao , Pavlos Nikolopoulos , Christina Fragouli

This study proposes a method for imbalanced data classification based on deep probabilistic graphical models (DPGMs) to solve the problem that traditional methods have insufficient learning ability for minority class samples. To address the…

Machine Learning · Computer Science 2025-04-09 Yujia Lou , Jie Liu , Yuan Sheng , Jiawei Wang , Yiwei Zhang , Yaokun Ren

We consider a new group testing model wherein each item is a binary random variable defined by an a priori probability of being defective. We assume that each probability is small and that items are independent, but not necessarily…

Information Theory · Computer Science 2018-07-24 Tongxin Li , Chun Lam Chan , Wenhao Huang , Tarik Kaced , Sidharth Jaggi

Group testing is the combinatorial problem of identifying the defective items in a population by grouping items into test pools. Recently, nonadaptive group testing - where all the test pools must be decided on at the start - has been…

Information Theory · Computer Science 2013-01-31 Matthew Aldridge

Group testing is utilized in the case when we want to find a few defectives among large amount of items. Testing n items one by one requires n tests, but if the ratio of defectives is small, group testing is an efficient way to reduce the…

Computation · Statistics 2024-05-16 Hiroyasu Matsushima , Yusuke Tajima , Xiao-Nan Lu , Masakazu Jimbo

Probabilistic dependency graphs (PDGs) are a flexible class of probabilistic graphical models, subsuming Bayesian Networks and Factor Graphs. They can also capture inconsistent beliefs, and provide a way of measuring the degree of this…

Data Structures and Algorithms · Computer Science 2023-11-10 Oliver E. Richardson , Joseph Y. Halpern , Christopher De Sa

We consider a zero-error probabilistic group testing problem where individuals are defective independently but not with identical probabilities. We propose a greedy set formation method to build sets of individuals to be tested together. We…

Information Theory · Computer Science 2021-08-30 Mustafa Doger , Sennur Ulukus

Efficiently counting or detecting defective items is a crucial task in various fields ranging from biological testing to quality control to streaming algorithms. The \emph{group testing estimation problem} concerns estimating the number of…

Data Structures and Algorithms · Computer Science 2023-12-08 Nader H. Bshouty , Tsun-Ming Cheung , Gergely Harcos , Hamed Hatami , Anthony Ostuni

Recent advances and achievements of artificial intelligence (AI) as well as deep and graph learning models have established their usefulness in biomedical applications, especially in drug-drug interactions (DDIs). DDIs refer to a change in…

Predicting drug side-effects before they occur is a key task in keeping the number of drug-related hospitalizations low and to improve drug discovery processes. Automatic predictors of side-effects generally are not able to process the…

Machine Learning · Statistics 2022-12-01 Pietro Bongini , Elisa Messori , Niccolò Pancino , Monica Bianchini

In this paper, we introduce a variation of the group testing problem where each test is specified by an ordered subset of items and returns the first defective item in the specified order or returns null if there are no defectives. We refer…

Information Theory · Computer Science 2024-09-30 Waqar Mirza , Nikhil Karamchandani , Niranjan Balachandran

Union-free codes and disjunctive codes are two combinatorial structures, which are used in nonadaptive group testing to find a set of $d$ defective elements among $n$ samples by carrying out the minimal number of tests $t$. It is known that…

Information Theory · Computer Science 2022-01-13 Ilya Vorobyev

Graph serves as a powerful tool for modeling data that has an underlying structure in non-Euclidean space, by encoding relations as edges and entities as nodes. Despite developments in learning from graph-structured data over the years, one…

Machine Learning · Computer Science 2022-12-20 Tianxiang Zhao , Dongsheng Luo , Xiang Zhang , Suhang Wang

A detection system, modeled in a graph, is composed of "detectors" positioned at a subset of vertices in order to uniquely locate an ``intruder" at any vertex. \emph{Identifying codes} use detectors that can sense the presence or absence of…

Combinatorics · Mathematics 2021-12-06 Devin C. Jean , Suk J. Seo

The identification of active binding drugs for target proteins (termed as drug-target interaction prediction) is the key challenge in virtual screening, which plays an essential role in drug discovery. Although recent deep learning-based…

Machine Learning · Computer Science 2021-10-18 Siyuan Liu , Yusong Wang , Tong Wang , Yifan Deng , Liang He , Bin Shao , Jian Yin , Nanning Zheng , Tie-Yan Liu

In one-stage or non-adaptive group testing, instead of testing every sample unit individually, they are split, bundled in pools, and simultaneously tested. The results are then decoded to infer the states of the individual items. This…

Applications · Statistics 2020-12-04 Christoph Schumacher , Matthias Täufer