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We use topological data analysis to study neural population activity in the Sensorium 2023 dataset, which records responses from thousands of mouse visual cortex neurons to diverse video stimuli. For each video, we build frame-by-frame…

Algebraic Topology · Mathematics 2026-03-04 Yuri Gardinazzi , Alessio Ansuini , Eugenio Piasini , Fabio Anselmi , Matteo Biagetti

In this report trial-to-trial variations in the synchronized responses of neural networks are offered as evidence for excitation-inhibition ratio being a dynamic variable over time scales of minutes. Synchronized network responses to…

Neurons and Cognition · Quantitative Biology 2015-01-05 Netta Haroush , Shimon Marom

Decoding stimuli or behaviour from recorded neural activity is a common approach to interrogate brain function in research, and an essential part of brain-computer and brain-machine interfaces. Reliable decoding even from small neural…

Neurons and Cognition · Quantitative Biology 2023-01-06 Justin Jude , Matthew G. Perich , Lee E. Miller , Matthias H. Hennig

A convolution model which accounts for neural activity dynamics in the primary visual cortex is derived and used to detect visually salient contours in images. Image inputs to the model are modulated by long-range horizontal connections,…

Biological Physics · Physics 2011-03-21 P. N. Loxley , L. M. Bettencourt

The need for more transparency of the decision-making processes in artificial neural networks steadily increases driven by their applications in safety critical and ethically challenging domains such as autonomous driving or medical…

Neural and Evolutionary Computing · Computer Science 2020-05-12 Richard Meyes , Constantin Waubert de Puiseau , Andres Posada-Moreno , Tobias Meisen

We study the capacity with which a system of independent neuron-like units represents a given set of stimuli. We assume that each neuron provides a fixed amount of information, and that the information provided by different neurons has a…

Disordered Systems and Neural Networks · Physics 2007-05-23 Ines Samengo

Brains adapt to the statistical structure of their input. In the visual system, local light intensities change rapidly, the variance of the intensity changes more slowly, and the dynamic range of contrast itself changes more slowly still.…

Neurons and Cognition · Quantitative Biology 2025-09-03 Charles J. Edelson , Sima Setayeshgar , William Bialek , Rob R. de Ruyter van Steveninck

It is a principal open question whether noninvasive imaging methods in humans can decode information encoded at a spatial scale as fine as the basic functional unit of cortex: cortical columns. We addressed this question in five…

Neurons and Cognition · Quantitative Biology 2015-03-30 Radoslaw Martin Cichy , Dimitrios Pantazis

A key question in neuroscience is at which level functional meaning emerges from biophysical phenomena. In most vertebrate systems, precise functions are assigned at the level of neural populations, while single-neurons are deemed…

Neurons and Cognition · Quantitative Biology 2017-03-17 Wieland Brendel , Ralph Bourdoukan , Pietro Vertechi , Christian K. Machens , Sophie Denéve

To gain insight into the neural events responsible for visual perception of static and dynamic optical patterns, we study how neural activation spreads in arrays of inhibition-stabilized neural networks with nearest-neighbor coupling. The…

Neurons and Cognition · Quantitative Biology 2016-09-02 Sergey Savel'ev , Sergei Gepshtein

Information processing in the brain is conducted by a concerted action of multiple neural populations. Gaining insights in the organization and dynamics of such populations can best be studied with broadband intracranial recordings of…

The spatiotemporal patterns of neural dynamics are jointly shaped by directed structural interactions and heterogeneous intrinsic features of the neural components. Despite well-developed methods for estimating directionality in network…

Neurons and Cognition · Quantitative Biology 2025-10-07 Jiawen Chang , Zhuda Yang , Changsong Zhou

Over the last decade, next-generation neural mass models have become increasingly prominent in mathematical neuroscience. These models link microscopic dynamics with low-dimensional systems of so-called firing rate equations that exactly…

Neurons and Cognition · Quantitative Biology 2024-09-30 Bastian Pietras , Ernest Montbrió

When selective attention is devoted to one of multiple stimuli within receptive fields of neurons in visual area V4, cells respond as if only the attended stimulus was present. The underlying neural mechanisms are still debated, but…

Neurons and Cognition · Quantitative Biology 2023-05-25 Lukas-Paul Rausch , Maik Schünemann , Eric Drebitz , Daniel Harnack , Udo A. Ernst , Andreas K. Kreiter

Understanding the activity of large populations of neurons is difficult due to the combinatorial complexity of possible cell-cell interactions. To reduce the complexity, coarse-graining had been previously applied to experimental neural…

Neurons and Cognition · Quantitative Biology 2021-03-24 Mia C. Morrell , Audrey J. Sederberg , Ilya Nemenman

A central goal of evolutionary biology is to explain the origins and distribution of diversity across life. Beyond species or genetic diversity, we also observe diversity in the circuits (genetic or otherwise) underlying complex functional…

Populations and Evolution · Quantitative Biology 2018-06-06 Ali Tehrani-Saleh , Thomas LaBar , Christoph Adami

The complex multi-stage architecture of cortical visual pathways provides the neural basis for efficient visual object recognition in humans. However, the stage-wise computations therein remain poorly understood. Here, we compared temporal…

Computer Vision and Pattern Recognition · Computer Science 2016-01-13 Radoslaw M. Cichy , Aditya Khosla , Dimitrios Pantazis , Antonio Torralba , Aude Oliva

Most sensory cells use surface receptors to detect environmental stimuli and initiate downstream signaling. Cooperative interactions among sensory receptors is known to play a crucial role in enhancing the sensitivity of biochemical…

Molecular Networks · Quantitative Biology 2014-01-15 Jianmin Sun , Michael Grabe

Deep neural networks, including recurrent networks, have been successfully applied to human activity recognition. Unfortunately, the final representation learned by recurrent networks might encode some noise (irrelevant signal components,…

Machine Learning · Computer Science 2018-10-10 Ming Zeng , Haoxiang Gao , Tong Yu , Ole J. Mengshoel , Helge Langseth , Ian Lane , Xiaobing Liu

Spike synchrony, which occurs in various cortical areas in response to specific perception, action and memory tasks, has sparked a long-standing debate on the nature of temporal organization in cortex. One prominent view is that this type…

Neurons and Cognition · Quantitative Biology 2017-12-18 Clemens Korndörfer , Ekkehard Ullner , Jordi García-Ojalvo , Gordon Pipa