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The retina is one of the best known quantum detectors with rods able to respond to a single photon. However, estimates on the number of photons eliciting conscious perception, based on signal detection theory, are systematically above these…

According to the theory of efficient coding, sensory systems are adapted to represent natural scenes with high fidelity and at minimal metabolic cost. Testing this hypothesis for sensory structures performing non-linear computations on high…

Neurons and Cognition · Quantitative Biology 2018-04-13 Ulisse Ferrari , Christophe Gardella , Olivier Marre , Thierry Mora

The traditional view of neural computation in the cerebral cortex holds that sensory neurons are specialized, i.e., selective for certain dimensions of sensory stimuli. This view was challenged by evidence of contextual interactions between…

Neurons and Cognition · Quantitative Biology 2022-04-26 Sergei Gepshtein , Ambarish Pawar , Sunwoo Kwon , Sergey Savel'ev , Thomas D. Albright

Human language processing relies on the brain's capacity for predictive inference. We present a machine learning framework for decoding neural (EEG) responses to dynamic visual language stimuli in Deaf signers. Using coherence between…

Neurons and Cognition · Quantitative Biology 2025-12-25 Sean C. Borneman , Julia Krebs , Ronnie B. Wilbur , Evie A. Malaia

This PhD thesis is focused on the central idea that single neurons in the brain should be regarded as temporally precise and highly complex spatio-temporal pattern recognizers. This is opposed to the prevalent view of biological neurons as…

Neurons and Cognition · Quantitative Biology 2023-09-27 David Beniaguev

Detecting dynamic patterns of task-specific responses shared across heterogeneous datasets is an essential and challenging problem in many scientific applications in medical science and neuroscience. In our motivating example of rodent…

Neurons and Cognition · Quantitative Biology 2024-07-02 Yubai Yuan , Babak Shahbaba , Norbert Fortin , Keiland Cooper , Qing Nie , Annie Qu

Identifying cell types and understanding their functional properties is crucial for unraveling the mechanisms underlying perception and cognition. In the retina, functional types can be identified by carefully selected stimuli, but this…

Human behavior understanding is arguably one of the most important mid-level components in artificial intelligence. In order to efficiently make use of data, multi-task learning has been studied in diverse computer vision tasks including…

Computer Vision and Pattern Recognition · Computer Science 2018-02-15 Dong-Jin Kim , Jinsoo Choi , Tae-Hyun Oh , Youngjin Yoon , In So Kweon

Single neurons in neural networks are often interpretable in that they represent individual, intuitively meaningful features. However, many neurons exhibit $\textit{mixed selectivity}$, i.e., they represent multiple unrelated features. A…

Machine Learning · Statistics 2023-10-19 David Klindt , Sophia Sanborn , Francisco Acosta , Frédéric Poitevin , Nina Miolane

Systems neuroscience relies on two complementary views of neural data, characterized by single neuron tuning curves and analysis of population activity. These two perspectives combine elegantly in neural latent variable models that…

Understanding how neural networks process complex patterns of information is crucial for advancing both neuroscience and artificial intelligence. To investigate fundamental principles of neural computation, we studied dissociated neuronal…

Neurons and Cognition · Quantitative Biology 2025-03-03 Zhuo Zhang , Amit Yaron , Dai Akita , Tomoyo Isoguchi Shiramatsu , Zenas C. Chao , Hirokazu Takahashi

We apply an information theoretic treatment of action potential time series measured with microelectrode arrays to estimate the connectivity of mammalian neuronal cell assemblies grown {\it in vitro}. We infer connectivity between two…

Neurons and Cognition · Quantitative Biology 2007-05-23 Luis M. A. Bettencourt , Greg J. Stephens , Michael I. Ham , Guenter W. Gross

Spontaneous cortical population activity exhibits a multitude of oscillatory patterns, which often display synchrony during slow-wave sleep or under certain anesthetics and stay asynchronous during quiet wakefulness. The mechanisms behind…

Neurons and Cognition · Quantitative Biology 2018-06-20 Rodrigo F. O. Pena , Michael A. Zaks , Antonio C. Roque

Receptive profiles of V1 cortical cells are very heterogeneous and act by differentiating the stimulus image as operators changing from point to point. A lightness and color constancy image can be reconstructed as the solution of the…

Analysis of PDEs · Mathematics 2023-08-01 Alessandro Sarti , Mattia Galeotti , Giovanna Citti

Neural populations encode information about their stimulus in a collective fashion, by joint activity patterns of spiking and silence. A full account of this mapping from stimulus to neural activity is given by the conditional probability…

Neurons and Cognition · Quantitative Biology 2013-06-14 Einat Granot-Atedgi , Gašper Tkačik , Ronen Segev , Elad Schneidman

Recent studies have shown how spiking networks can learn complex functionality through error-correcting plasticity, but the resulting structures and dynamics remain poorly studied. To elucidate how these models may link to observed dynamics…

Neurons and Cognition · Quantitative Biology 2025-08-19 Jonas Oberste-Frielinghaus , Anno C. Kurth , Julian Göltz , Laura Kriener , Junji Ito , Mihai A. Petrovici , Sonja Grün

The functional significance of correlations between action potentials of neurons is still a matter of vivid debates. In particular it is presently unclear how much synchrony is caused by afferent synchronized events and how much is…

Neurons and Cognition · Quantitative Biology 2013-04-09 Matthias Schultze-Kraft , Markus Diesmann , Sonja Grün , Moritz Helias

Statistical similarities between neuronal spike trains could reveal significant information on complex underlying processing. In general, the similarity between synchronous spike trains is somewhat easy to identify. However, the similar…

Neurons and Cognition · Quantitative Biology 2021-03-16 Sathish Ande , Jayanth R Regatti , Neha Pandey , Ajith Karunarathne , Lopamudra Giri , Soumya Jana

Despite significant strides in visual quality assessment, the neural mechanisms underlying visual quality perception remain insufficiently explored. This study employed fMRI to examine brain activity during image quality assessment and…

Multimedia · Computer Science 2024-04-30 Yiming Zhang , Ying Hu , Xiongkuo Min , Yan Zhou , Guangtao Zhai

Neural circuits often face the problem of classifying stimuli into discrete groups and making decisions based on such classifications. Neurons of these circuits can be distinguished according to their correlations with different features of…

Neurons and Cognition · Quantitative Biology 2007-05-23 Alexei A. Koulakov , Dmitry Rinberg , Dmitry N. Tsigankov
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