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The mutual information between stimulus and spike-train response is commonly used to monitor neural coding efficiency, but neuronal computation broadly conceived requires more refined and targeted information measures of input-output joint…

Neurons and Cognition · Quantitative Biology 2015-04-21 Sarah E. Marzen , Michael R. DeWeese , James P. Crutchfield

Understanding physical rules underlying collective motions requires perturbation of controllable parameters in self-propelled particles. However, controlling parameters in animals is generally not easy, which makes collective behaviours of…

Biological Physics · Physics 2019-01-31 Takuma Sugi , Hiroshi Ito , Masaki Nishimura , Ken H. Nagai

The resting brain dynamics self-organizes into a finite number of correlated patterns known as resting state networks (RSNs). It is well known that techniques like independent component analysis can separate the brain activity at rest to…

Animal behavior is often quantified through subjective, incomplete variables that may mask essential dynamics. Here, we develop a behavioral state space in which the full instantaneous state is smoothly unfolded as a combination of…

Neurons and Cognition · Quantitative Biology 2019-12-02 Tosif Ahamed , Antonio Carlos Costa , Greg J. Stephens

A fundamental problem in neuroscience is understanding how a network's properties dictate its function. Connectomics provides one avenue to predict nervous system function. To test this explicitly, we systematically measure signal…

Neurons and Cognition · Quantitative Biology 2023-11-09 Francesco Randi , Anuj K. Sharma , Sophie Dvali , Andrew M. Leifer

The pharynx of the nematode Caenorhabditis elegans is a neuromuscular pump that exhibits two typical motions: pumping and peristalsis. While the dynamics of these motions are well characterized, the underlying mechanisms generating most of…

Neurons and Cognition · Quantitative Biology 2019-03-29 Dana Sherman , David Harel

Sensory neurons give highly variable responses to stimulation, which can limit the amount of stimulus information available to downstream circuits. Much work has investigated the factors that affect the amount of information encoded in…

Neurons and Cognition · Quantitative Biology 2017-04-20 Joel Zylberberg , Alexandre Pouget , Peter E. Latham , Eric Shea-Brown

A spiral wave is a macroscopic dynamic of excitable media that plays an important role in several distinct systems, including the Belousov-Zhabotinsky reaction, seizures in the brain, and lethal arrhythmia in the heart. Because spiral wave…

Pattern Formation and Solitons · Physics 2018-02-02 Hiroshi Ashikaga , Ryan G. James

Visual encoding and decoding models act as gateways to understanding the neural mechanisms underlying human visual perception. Typically, visual encoding models that predict brain activity from stimuli and decoding models that reproduce…

Machine Learning · Computer Science 2026-04-14 Weijian Mai , Mu Nan , Yu Zhu , Jiahang Cao , Rui Zhang , Yuqin Dai , Chunfeng Song , Andrew F. Luo , Jiamin Wu

The neural dynamics of the nematode C. elegans are experimentally low-dimensional and correspond to discrete behavioral states, where previous modeling work has found neural proxies for some of these states. Experimental results further…

Neurons and Cognition · Quantitative Biology 2015-09-04 James Kunert , Eli Shlizerman , Andrew Walker , J. Nathan Kutz

Understanding principles of neurolocomotion requires the synthesis of neural activity, sensory feedback, and biomechanics. The nematode \textit{C. elegans} is an ideal model organism for studying locomotion in an integrated neuromechanical…

Neurons and Cognition · Quantitative Biology 2021-06-08 Carter L. Johnson , Timothy J. Lewis , Robert D. Guy

Brain research has been driven by enquiry for principles of brain structure organization and its control mechanisms. The neuronal wiring map of C. elegans, the only complete connectome available till date, presents an incredible opportunity…

Neurons and Cognition · Quantitative Biology 2016-11-28 Rahul Badhwar , Ganesh Bagler

In the brain, information is encoded, transmitted and used to inform behaviour at the level of timing of action potentials distributed over population of neurons. To implement neural-like systems in silico, to emulate neural function, and…

Neural and Evolutionary Computing · Computer Science 2022-12-09 Stefano Panzeri , Ella Janotte , Alejandro Pequeño-Zurro , Jacopo Bonato , Chiara Bartolozzi

Neural communication operates on both fast synaptic transmission and slower, diffusive extrasynaptic signaling, yet how these two modes jointly organize brain function remains unclear. Here, using the complete synaptic and neuropeptidergic…

Neurons and Cognition · Quantitative Biology 2026-04-03 Giridhar Sunil , Habib Benali , Elkaïoum M. Moutuou

Understanding information processing in the brain requires the ability to determine the functional connectivity between the different regions of the brain. We present a method using transfer entropy to extract this flow of information…

Neurons and Cognition · Quantitative Biology 2019-03-06 Benjamin Walker , Katherine Newhall

We propose a working hypothesis supported by numerical simulations that brain networks evolve based on the principle of the maximization of their internal information flow capacity. We find that synchronous behavior and capacity of…

Neurons and Cognition · Quantitative Biology 2015-08-17 Chris G. Antonopoulos , Shambhavi Srivastava , Sandro E. de S. Pinto , Murilo S. Baptista

C. elegans is commonly used in neuroscience for behaviour analysis because of it's compact nervous system with well-described connectivity. Localizing the animal and distinguishing between its head and tail are important tasks to track the…

Computer Vision and Pattern Recognition · Computer Science 2020-01-14 Mansi Ranjit Mane , Aniket Anand Deshmukh , Adam J. Iliff

The informational synthesis of neural structures, processes, parameters and characteristics that allow a unified description and modeling as neural machines of natural and artificial neural systems is presented. The general informational…

Neural and Evolutionary Computing · Computer Science 2024-04-08 Iosif Iulian Petrila

In the intricate architecture of the mammalian central nervous system, neurons form populations. Axonal bundles communicate between these clusters using spike trains. However, these neuron populations' precise encoding and operations have…

Neurons and Cognition · Quantitative Biology 2024-01-02 Martin N. P. Nilsson

An information-theoretic framework known as integrated information theory (IIT) has been introduced recently for the study of the emergence of consciousness in the brain [D. Balduzzi and G. Tononi, PLoS Comput. Biol. 4, e1000091 (2008)].…

Neurons and Cognition · Quantitative Biology 2011-07-11 Andre Nathan , Valmir C. Barbosa
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