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This work demonstrates a computational method for predicting the light propagation through a single multimode fiber using a deep neural network. The experiment for gathering training and testing data is performed with a digital micro-mirror…

Optics · Physics 2018-12-10 Pengfei Fan , Liang Deng , Lei Su

In this letter, we present a genetic algorithm-based approach for image retrieval through a multimode fiber in a reference-less system. Due to mode interference, when an image is illuminated at one side of a multimode fiber, the transmitted…

Image and Video Processing · Electrical Eng. & Systems 2018-11-16 Michael Ruddlesden , Jinshuai Zhang , Tianrui Zhao , Wen Wang , Lei Su

Lensless illumination single-pixel imaging with a multicore fiber (MCF) is a computational imaging technique that enables potential endoscopic observations of biological samples at cellular scale. In this work, we show that this technique…

Signal Processing · Electrical Eng. & Systems 2023-07-18 Olivier Leblanc , Matthias Hofer , Siddharth Sivankutty , Hervé Rigneault , Laurent Jacques

Melanoma detection is vital for early diagnosis and effective treatment. While deep learning models on dermoscopic images have shown promise, they require specialized equipment, limiting their use in broader clinical settings. This study…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Volodymyr Sydorskyi , Igor Krashenyi , Oleksii Yakubenko

We demonstrate a new computational illumination technique that achieves large space-bandwidth-time product, for quantitative phase imaging of unstained live samples in vitro. Microscope lenses can have either large field of view (FOV) or…

Optics · Physics 2015-10-16 Lei Tian , Ziji Liu , Li-Hao Yeh , Michael Chen , Jingshan Zhong , Laura Waller

Endoscopy has been an indispensible tool in medical diagnostics, and yet the demands for reduced unit diameter and enhanced spatial resolution have steadily been growing for the accurate investigation of distal sites with minimal side…

The usage of a GaAsP (gallium arsenide phosphide) photomultiplier for microscopical imaging allows the evaluation of low-light luminescent objects. We designed a setup for collecting a confocal microscopic image signal, which is divided…

Fiber-based micro-endoscopes are a critically important tool for minimally-invasive deep-tissue imaging. However, the state-of-the-art micro-endoscopes cannot perform three-dimensional imaging through dynamically-bent fibers without the use…

Optics · Physics 2022-11-09 Noam Badt , Ori Katz

Scanning microscopy systems, such as confocal and multiphoton microscopy, are powerful imaging tools for probing deep into biological tissue. However, scanning systems have an inherent trade-off between acquisition time, field of view,…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Cassandra Tong Ye , Jiashu Han , Kunzan Liu , Anastasios Angelopoulos , Linda Griffith , Kristina Monakhova , Sixian You

Multimode fibers are attractive for a variety of applications such as internet data transfer, data center hubs, micromanipulation, optogenetics and other biomedical applications. A major hurdle for imaging through multimode fibers is the…

Mid-infrared hyperspectral imaging has become an indispensable tool to spatially resolve chemical information in a wide variety of samples. However, acquiring three-dimensional data cubes is typically time-consuming due to the limited speed…

Optics · Physics 2026-05-29 Jianan Fang , Kun Huang , Ruiyang Qin , Yan Liang , E Wu , Ming Yan , Heping Zeng

In this paper we apply digital in-line holography to image opaque objects through a thick plano-concave pipe. Opaque fibers and opaque particles are considered}. Analytical expression of the intensity distribution in the CCD sensor plane is…

Optics · Physics 2012-12-21 Nicolas Verrier , Coëtmellec Sébastien , Brunel Marc , Lebrun Denis

Dual-comb microscopy (DCM), an interesting imaging modality based on the optical-frequency-comb (OFC) mode and image pixel one-to-one correspondence, benefits from scan-less full-field imaging and simultaneous confocal amplitude and phase…

Multimode fibers (MMFs) have the potential to carry complex images for endoscopy and related applications, but decoding the complex speckle patterns produced by mode-mixing and modal dispersion in MMFs is a serious challenge. Several groups…

Image and Video Processing · Electrical Eng. & Systems 2020-09-02 Changyan Zhu , Eng Aik Chan , You Wang , Weina Peng , Ruixiang Guo , Baile Zhang , Cesare Soci , Yidong Chong

Multimode fibres are becoming increasingly attractive in optical endoscopy as they promise to enable unparalleled miniaturisation, spatial resolution and cost as compared to conventional fibre bundle-based counterpart. However, achieving…

Medical Physics · Physics 2024-06-05 Tianrui Zhao , Michelle T. Ma , Sebastien Ourselin , Tom Vercauteren , Wenfeng Xia

Widefield microscopy methods applied to optically thick specimens are faced with reduced contrast due to spatial crosstalk, in which the signal at each point is the result of a superposition from neighboring points that are simultaneously…

An improved method of remote optical absorption spectroscopy and hyperspectral optical absorption imaging is described which takes advantage of the photoacoustic remote sensing detection architecture. A wide range of photoacoustic…

Biological Physics · Physics 2021-08-04 Kevan Bell , Lyazzat Mukhangaliyeva , Layla Khalili , Parsin Haji Reza

For several centuries, far-field optical microscopy has remained a key instrument in many scientific disciplines including physical, chemical and biomedical research. Nonetheless, far-field imaging has many limitations: the spatial…

Optics · Physics 2020-01-27 Lyubov V. Amitonova , Johannes F. de Boer

Extracting meaningful information about unknown quantum states without performing a full tomography is an important task. Low-dimensional projections and random measurements can provide such insight but typically require careful crafting.…

Transmission matrix (TM) allows light control through complex media such as multimode fibers (MMFs), gaining great attention in areas like biophotonics over the past decade. The measurement of a complex-valued TM is highly desired as it…

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