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Measuring the statistical dependence between observed signals is a primary tool for scientific discovery. However, biological systems often exhibit complex non-linear interactions that currently cannot be captured without a priori knowledge…

Recent advances in mathematical reasoning and the long-term planning capabilities of large language models (LLMs) have precipitated the development of agents, which are being increasingly leveraged in business operations processes. Decision…

Artificial Intelligence · Computer Science 2025-08-18 Xuhua Zhao , Yuxuan Xie , Caihua Chen , Yuxiang Sun

In contrast to the popular Cox model which presents a multiplicative covariate effect specification on the time to event hazards, the semiparametric additive risks model (ARM) offers an attractive additive specification, allowing for direct…

Methodology · Statistics 2022-03-21 Tong Wang , Dipankar Bandyopadhyay , Samiran Sinha

Model merging, a method that combines the parameters and embeddings of multiple fine-tuned large language models (LLMs), offers a promising approach to enhance model performance across various tasks while maintaining computational…

Computation and Language · Computer Science 2025-11-10 Amin Heyrani Nobari , Kaveh Alim , Ali ArjomandBigdeli , Akash Srivastava , Faez Ahmed , Navid Azizan

Measurement non-invariance arises when the psychometric properties of a scale differ across subgroups, undermining the validity of group comparisons. At the item level, such non-invariance manifests as differential item functioning (DIF),…

Methodology · Statistics 2026-01-27 Gabriel Wallin , Qi Huang

Agent-based models (ABMs) are widely used to study infectious disease dynamics, but their calibration is often computationally intensive, limiting their applicability in time-sensitive public health settings. We propose DeepIMC (Deep…

Machine Learning · Computer Science 2026-04-03 Sima Najafzadehkhoei , George Vega Yon , Derek S. Meyer , Bernardo Modenesi

Log-symmetric regression models are particularly useful when the response variable is continuous, strictly positive and asymmetric. In this paper, we proposed a class of log-symmetric regression models in the context of correlated errors.…

Methodology · Statistics 2018-10-22 Helton Saulo , Roberto Vila

Item response theory (IRT) models explain an observed item response as a function of a respondent's latent trait and the item's property. IRT is one of the most widely utilized tools for item response analysis; however, local item and…

Applications · Statistics 2025-01-08 Ick Hoon Jin , Minjeong Jeon

Linear regression on network-linked observations has been an essential tool in modeling the relationship between response and covariates with additional network structures. Previous methods either lack inference tools or rely on restrictive…

Methodology · Statistics 2022-08-22 Can M. Le , Tianxi Li

As agentic AI becomes more widespread, agents with distinct and possibly conflicting goals will interact in complex ways. These multi-agent interactions pose a fundamental challenge, particularly in social dilemmas, where agents' individual…

Machine Learning · Computer Science 2025-12-02 Dereck Piche , Mohammed Muqeeth , Milad Aghajohari , Juan Duque , Michael Noukhovitch , Aaron Courville

Additive models enjoy the flexibility of nonlinear models while still being readily understandable to humans. By contrast, other nonlinear models, which involve interactions between features, are not only harder to fit but also…

Methodology · Statistics 2025-06-03 Yiling Huang , Snigdha Panigrahi , Guo Yu , Jacob Bien

One of the central objectives of modern risk management is to find a set of risks where the probability of multiple simultaneous catastrophic events is negligible. That is, risks are taken only when their joint behavior seems sufficiently…

Statistics Theory · Mathematics 2019-04-02 Jaakko Lehtomaa , Sidney Resnick

Asymmetric causality tests are increasingly gaining popularity in different scientific fields. This approach corresponds better to reality since logical reasons behind asymmetric behavior exist and need to be considered in empirical…

Econometrics · Economics 2024-10-10 Abdulnasser Hatemi-J

Alzheimer's Disease Analysis Model (ADAM) is a multi-agent reasoning large language model (LLM) framework designed to integrate and analyze multimodal data, including microbiome profiles, clinical datasets, and external knowledge bases, to…

Artificial Intelligence · Computer Science 2025-08-22 Ziyuan Huang , Vishaldeep Kaur Sekhon , Roozbeh Sadeghian , Maria L. Vaida , Cynthia Jo , Doyle Ward , Vanni Bucci , John P. Haran

In applications of linear mixed-effects models, experimenters often desire uncertainty quantification for random quantities, like predicted treatment effects for unobserved individuals or groups. For example, consider an agricultural…

Methodology · Statistics 2022-10-19 Nicholas Syring , Fernando Miguez , Jarad Niemi

We derive an asymptotic power function for a likelihood-based test for interaction in a regression model, with possibly misspecified alternative distribution. This allows a general investigation of types of interactions which are poorly or…

Statistics Theory · Mathematics 2007-11-27 Juxin Liu , Paul Gustafson

Experiments often yield non-identically distributed data for statistical analysis. Tests of hypothesis under such set-ups are generally performed using the likelihood ratio test, which is non-robust with respect to outliers and model…

Statistics Theory · Mathematics 2017-07-25 Abhik Ghosh , Ayanendranath Basu

We investigate the emergent collective dynamics of LLM-based multi-agent systems on a 2D square lattice and present a model-agnostic statistical-physics method to disentangle social conformity from intrinsic bias, compute critical…

Statistical Mechanics · Physics 2026-05-12 Cristiano De Nobili

We propose a nonparametric test for serial independence that aggregates pairwise similarities of observations with lag-dependent weights. The resulting statistic is powerful to general forms of temporal dependence, including nonlinear and…

Methodology · Statistics 2025-09-09 Qihua Zhu , Mingshuo Liu , Yuefeng Han , Doudou Zhou

Large language model (LLM) systems are increasingly used to support high-stakes decision-making, but they typically perform worse when the available evidence is internally inconsistent. Such a scenario exists in real-world healthcare…

Computation and Language · Computer Science 2026-04-02 Haochen Liu , Weien Li , Rui Song , Zeyu Li , Chun Jason Xue , Xiao-Yang Liu , Sam Nallaperuma , Xue Liu , Ye Yuan