WISE: A Weighted Similarity Aggregation Test for Serial Independence

We propose a nonparametric test for serial independence that aggregates pairwise similarities of observations with lag-dependent weights. The resulting statistic is powerful to general forms of temporal dependence, including nonlinear and uncorrelated alternatives, and applies to ultra-high-dimensional and non-Euclidean data. We derive asymptotic normality under both permutation and population nulls, and establish consistency in classical large-sample and high-dimension-low-sample-size (HDLSS) regimes. The test therefore provides the first theoretical power guarantees for serial independence in the HDLSS setting. Simulations demonstrate accurate size and strong power against a wide range of alternatives, showing significant power improvement over existing methods under various high-dimensional time series models. An application to spatio-temporal data illustrates the method's utility for non-Euclidean observations.