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This letter is the first demonstration of material modification using tightly focused femtosecond laser vortex beams. Double-charge femtosecond vortices were synthesized with the polarization-singularity beam converter described in Ref [1]…

Despite more than 100 years of study, it is unclear if the movement of proteins inside the cell is best described as a mosh pit or an exquisitely choreographed dance. Recent studies suggest the latter. Local interactions induce molecular…

Quantitative Methods · Quantitative Biology 2023-08-25 James A. Galbraith , Catherine G. Galbraith

Single-shot X-ray imaging of short-lived nanostructures such as clusters and nanoparticles near a phase transition or non-crystalizing objects such as large proteins and viruses is currently the most elegant method for characterizing their…

Atomic and Molecular Clusters · Physics 2020-10-14 Thomas Stielow , Robin Schmidt , Christian Peltz , Thomas Fennel , Stefan Scheel

Glass forming liquids exhibit structural relaxation behaviors, reflecting underlying atomic rearrangements on a wide range of timescales. These behaviors play a crucial role in determining many material properties. However, the relaxation…

Femtosecond electron microscopy produces real-space images of matter in a series of ultrafast snapshots. Pulses of electrons self-disperse under space-charge broadening, so without compression, the ideal operation mode is a single electron…

Accelerator Physics · Physics 2016-04-21 A. R. Bainbridge , C. W. Barlow-Myers , W. A. Bryan

The presence of a pulse train structure of an oscillator-type free-electron laser (FEL) results in the immediate damage of a solid target upon focusing. We demonstrate that the laser-induced damage threshold can be significantly improved by…

This paper discusses the potential for enhancing the LCLS hard X-ray FEL capabilities. In the hard X-ray regime, a high longitudinal coherence will be the key to such performance upgrade. The method considered here to obtain high…

Accelerator Physics · Physics 2010-08-19 Gianluca Geloni , Vitali Kocharyan , Evgeni Saldin

We investigate the dynamics of diatomic molecules subjected to both a femtosecond mid-infrared laser pulse and Gaussian white noise. The stochastic Schr\"odinger equation with a Morse potential is used to describe the molecular vibrations…

Quantum Physics · Physics 2009-11-13 Kamal P. Singh , Anatole Kenfack , Jan M. Rost

Modern technology for producing extremely bright and coherent X-ray laser pulses provides the possibility to acquire a large number of diffraction patterns from individual biological nanoparticles, including proteins, viruses, and DNA.…

Methodology · Statistics 2018-07-11 Stefan Engblom , Carl Nettelblad , Jing Liu

The dissociation dynamics of diatomic molecules interacting with (near) optical laser pulses of different duration is investigated by an elaborate discussion of the electric field of the laser and by a direct solution of the time-dependent…

Atomic Physics · Physics 2019-08-14 T. Fiedlschuster , J. Handt , E. K. U. Gross , R. Schmidt

On the basis of a quantum microscopic approach we study the dynamics of the afterglow of a dilute Gaussian atomic ensemble excited by pulsed radiation. Taking into account the vector nature of the electromagnetic field we analyze in detail…

Quantum Physics · Physics 2017-08-23 A. S. Kuraptsev , I. M. Sokolov , M. D. Havey

We demonstrate a tilted pulse-front transient grating technique that allows to optimally utilize time-resolution as well as transient grating line density while probing under grazing incidence as typically done in extreme ultraviolet (EUV)…

Instrumentation and Detectors · Physics 2018-08-29 A. Battistoni , H. A. Dürr , M. Gühr , T. J. A. Wolf

Radiation damage is considered to be the major problem that still prevents imaging an individual biological molecule for structural analysis. So far, all known mapping techniques using sufficient short wave-length radiation, be it X-rays or…

Biological Physics · Physics 2010-10-28 Matthias Germann , Tatiana Latychevskaia , Conrad Escher , Hans-Werner Fink

Optical techniques for spatiotemporal control can produce laser pulses with custom amplitude, phase, or polarization structure. In nonlinear optics and plasma physics, the use of structured pulses typically follows a forward design…

X-ray absorption spectroscopy (XAS) is a powerful and well established technique with sensitivity to elemental and chemical composition. Despite these advantages, its implementation has not kept pace with the development of ultrafast pulsed…

X-ray diffraction microscopy (XDM) is a new form of x-ray imaging that is being practiced at several third-generation synchrotron-radiation x-ray facilities. Although only five years have elapsed since the technique was first introduced, it…

The outstanding opto-electronic properties of lead halide perovskites have been related to the formation of polarons. Nevertheless, the observation of the atomistic deformation brought about by one electron-hole pair in these materials has…

Our knowledge on ultracold quantum gases is strongly influenced by our ability to probe these objects. In situ imaging combined with single atom sensitivity is an especially appealing scenario as it can provide direct information on the…

Other Condensed Matter · Physics 2008-05-01 Tatjana Gericke , Peter Würtz , Daniel Reitz , Tim Langen , Herwig Ott