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Random walks and related spatial stochastic models have been used in a range of application areas including animal and plant ecology, infectious disease epidemiology, developmental biology, wound healing, and oncology. Classical random walk…

Populations and Evolution · Quantitative Biology 2025-08-22 Michael J. Plank , Matthew J. Simpson , Ruth E. Baker

Analyzing the mixing time of random walks is a well-studied problem with applications in random sampling and more recently in graph partitioning. In this work, we present new analysis of random walks and evolving sets using more…

Data Structures and Algorithms · Computer Science 2015-07-09 Siu On Chan , Tsz Chiu Kwok , Lap Chi Lau

We study a discrete time self interacting random process on graphs, which we call Greedy Random Walk. The walker is located initially at some vertex. As time evolves, each vertex maintains the set of adjacent edges touching it that have not…

Probability · Mathematics 2019-02-20 Tal Orenshtein , Igor Shinkar

Organisms have evolved immune systems that can counter pathogenic threats. The adaptive immune system in vertebrates consists of a diverse repertoire of immune receptors that can dynamically reorganize to specifically target the…

Populations and Evolution · Quantitative Biology 2024-10-29 Quinn N Bellamy , Zachary Montague , Luca Peliti , Armita Nourmohammad

Motivation: Over the past decade, network-based approaches have proven useful in identifying disease modules within the human interactome, often providing insights into key mechanisms and guiding the quest for therapeutic targets. This is…

Quantitative Methods · Quantitative Biology 2022-11-30 Michele Gentili , Leonardo Martini , Marialuisa Sponziello , Luca Becchetti

We present a novel quasi-Monte Carlo mechanism to improve graph-based sampling, coined repelling random walks. By inducing correlations between the trajectories of an interacting ensemble such that their marginal transition probabilities…

Machine Learning · Statistics 2024-05-27 Isaac Reid , Eli Berger , Krzysztof Choromanski , Adrian Weller

Dynamic graphs have emerged as an appropriate model to capture the changing nature of many modern networks, such as peer-to-peer overlays and mobile ad hoc networks. Most of the recent research on dynamic networks has only addressed the…

Data Structures and Algorithms · Computer Science 2011-02-02 Oksana Denysyuk , Luis Rodrigues

Single particle tracking allows probing how biomolecules interact physically with their natural environments. A fundamental challenge when analysing recorded single particle trajectories is the inverse problem of inferring the physical…

Migratory and tissue resident cells exhibit highly branched morphologies to perform their function and to adapt to the microenvironment. Immune cells, for example, display transient branched shapes while exploring the surrounding tissues.…

Biological Physics · Physics 2024-04-02 Jiayi Liu , Javier Boix-Campos , Jonathan E. Ron , Johan M. Kux , Nir S. Gov , Pablo J. Sáez

The adaptive and innate branches of the vertebrate immune system work in close collaboration to protect organisms from harmful pathogens. As an organism ages its immune system undergoes immunosenescence, characterized by declined…

Tissues and Organs · Quantitative Biology 2020-08-28 Eric W. Jones , Jiming Sheng , Jean M. Carlson , Shenshen Wang

We propose a new paradigm to design a network-based self-adaptive epidemic model that relies on the interplay between the network and its line graph. We implement this proposal on a Susceptible-Infected-Susceptible model in which both nodes…

Adaptation and Self-Organizing Systems · Physics 2024-03-05 Paolo Bartesaghi , Gian Paolo Clemente , Rosanna Grassi

Different evolutionary models are known to make disparate predictions for the success of an invading mutant in some situations. For example, some evolutionary mechanics lead to amplification of selection in structured populations, while…

Populations and Evolution · Quantitative Biology 2020-07-01 Francisco Herrerías-Azcué , Vicente Pérez-Muñuzuri , Tobias Galla

Biological movement patterns can sometimes be quasi linear with abrupt changes in direction and speed, as in plastids in root cells investigated here. For the analysis of such changes we propose a new stochastic model for movement along…

Statistics Theory · Mathematics 2024-09-04 Solveig Plomer , Theresa Ernst , Philipp Gebhardt , Enrico Schleiff , Ralph Neininger , Gaby Schneider

The migratory dynamics of cells can be influenced by the complex micro-environment through which they move. It remains unclear how the motility machinery of confined cells responds and adapts to their micro-environment. Here, we propose a…

Biological Physics · Physics 2023-12-04 Johannes Flommersfeld , Stefan Stöberl , Omar Shah , Joachim O. Rädler , Chase P. Broedersz

Motivated by a problem arising from pharmaceutical science [B. Baeumer et al., Discr. Contin. Dyn. Sys. B 12], we study random walks on the contact graph of a bidisperse random sphere packing. For a random walk on the unweighted graph that…

Soft Condensed Matter · Physics 2011-03-08 Peter Hinow

We propose a model of random walks on weighted graphs where the weights are interval valued, and connect it to reversible imprecise Markov chains. While the theory of imprecise Markov chains is now well established, this is a first attempt…

Optimization and Control · Mathematics 2016-09-20 Damjan Škulj

Random walks on dynamic graphs have received increasingly more attention from different academic communities over the last decade. Despite the relatively large literature, little is known about random walks that construct the graph where…

The random walk with hyperbolic probabilities that we are introducing is an example of stochastic diffusion in a one-dimensional heterogeneous media. Although driven by site-dependent one-step transition probabilities, the process retains…

Statistical Mechanics · Physics 2021-06-03 Miquel Montero

We investigate a model of a parasite population invading spatially distributed immobile hosts on a graph, which is a modification of the frog model. Each host has an unbreakable immunity against infection with a certain probability $1-p$…

Probability · Mathematics 2026-01-27 Sascha Franck

B-cell repertoires are characterized by a diverse set of receptors of distinct specificities generated through two processes of somatic diversification: V(D)J recombination and somatic hypermutations. B cell clonal families stem from the…

Populations and Evolution · Quantitative Biology 2024-03-19 Natanael Spisak , Gabriel Athènes , Thomas Dupic , Thierry Mora , Aleksandra M. Walczak