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In a cellular medium, the plasmic membrane is a place of interactions between the cell and its direct external environment. A classic model describes it as a fluid mosaic. The fluid phase of the membrane allows a lateral degree of freedom…

Probability · Mathematics 2013-09-24 Aimé Lachal

Sood and Grassberger studied in [Phys. Rev. Lett. 99, 098701 (2007)] random walks on random graphs that are biased towards a fixed target point. They put forward a critical bias strength b_c such that a random walker on an infinite graph…

Statistical Mechanics · Physics 2009-11-13 O. Benichou , R. Voituriez

The mammalian adaptive immune system has evolved over millions of years to become an incredibly effective defense against foreign antigens. The adaptive immune system's humoral response creates plasma B cells and memory B cells, each with…

Cell Behavior · Quantitative Biology 2021-06-21 Stephen Lindsly , Maya Gupta , Cooper Stansbury , Indika Rajapakse

Immune cells learn about their antigenic targets using tactile sense: during recognition, a highly organized yet dynamic motif, named immunological synapse, forms between immune cells and antigen-presenting cells (APCs). Via synapses,…

Biological Physics · Physics 2018-12-12 Miloš Knežević , Shenshen Wang

The adaptive immune system constantly remodels its lymphocyte repertoire for better protection against future pathogens. Its ability to improve antigen recognition on the fly relies on somatic mutation and selective expansion of B…

Biological Physics · Physics 2022-09-29 Hongda Jiang , Shenshen Wang

We analyze the dynamics of a population of independent random walkers on a graph and develop a simple model of epidemic spreading. We assume that each walker visits independently the nodes of a finite ergodic graph in a discrete-time…

Physics and Society · Physics 2021-01-19 Michael Bestehorn , Alejandro P. Riascos , Thomas M. Michelitsch , Bernard A. Collet

The involution walk is the random walk on $S_n$ generated by involutions with a binomially distributed with parameter $1-p$ number of $2$-cycles. This is a parallelization of the transposition walk. The involution walk is shown in this…

Combinatorics · Mathematics 2016-07-05 Megan Bernstein

We consider random walks in which the walk originates in one set of nodes and then continues until it reaches one or more nodes in a target set. The time required for the walk to reach the target set is of interest in understanding the…

Systems and Control · Computer Science 2019-01-11 Andrew Clark , Basel Alomair , Linda Bushnell , Radha Poovendran

Message-passing architectures struggle to sufficiently model long-range dependencies in node and graph prediction tasks. We propose a novel approach exploiting hierarchical graph structures and adaptive random walks to address this…

Machine Learning · Computer Science 2025-09-03 Joël Mathys , Federico Errica

Random walk on changing graphs is considered. For sequences of finite graphs increasing monotonically towards a limiting infinite graph, we establish transition probability upper bounds. It yields sufficient transience criteria for simple…

Probability · Mathematics 2018-10-09 Ruojun Huang

Immune cells have evolved to recognize and eliminate pathogens, and the efficiency of this process can be measured in a Petri dish. Yet, even if the cells are time-lapse recorded and tracked with high resolution, it is difficult to judge…

Quantitative Methods · Quantitative Biology 2019-06-21 Claus Metzner

In this paper, we present a novel approach based on the random walk process for finding meaningful representations of a graph model. Our approach leverages the transient behavior of many short random walks with novel initialization…

Social and Information Networks · Computer Science 2018-05-14 Lin Li , William M. Campbell , Rajmonda S. Caceres

We study a system of random walks, known as the frog model, starting from a profile of independent Poisson($\lambda$) particles per site, with one additional active particle planted at some vertex $\mathbf{o}$ of a finite connected simple…

Probability · Mathematics 2025-07-08 Itai Benjamini , Luiz Renato Fontes , Jonathan Hermon , Fabio Prates Machado

B cells and the antibodies they produce are vital to health and survival, motivating research on the details of the mutational and evolutionary processes in the germinal centers (GC) from which mature B cells arise. It is known that B cells…

We quantify the VDJ recombination and somatic hypermutation processes in human B-cells using probabilistic inference methods on high-throughput DNA sequence repertoires of human B-cell receptor heavy chains. Our analysis captures the…

Populations and Evolution · Quantitative Biology 2016-02-10 Yuval Elhanati , Zachary Sethna , Quentin Marcou , Curtis G. Callan , Thierry Mora , Aleksandra M. Walczak

It is shown explicitly how self-similar graphs can be obtained as `blow-up' constructions of finite cell graphs $\hat C$. This yields a larger family of graphs than the graphs obtained by discretising continuous self-similar fractals. For a…

Combinatorics · Mathematics 2007-05-23 Bernhard Krön , Elmar Teufl

Graph-limit theory focuses on the convergence of sequences of graphs when the number of nodes becomes arbitrarily large. This framework defines a continuous version of graphs allowing for the study of dynamical systems on very large graphs,…

Probability · Mathematics 2020-05-20 Julien Petit , Renaud Lambiotte , Timoteo Carletti

In this paper, we introduce random walks with absorbing states on simplicial complexes. Given a simplicial complex of dimension $d$, a random walk with an absorbing state is defined which relates to the spectrum of the $k$-dimensional…

Combinatorics · Mathematics 2013-10-21 Sayan Mukherjee , John Steenbergen

We establish and generalise several bounds for various random walk quantities including the mixing time and the maximum hitting time. Unlike previous analyses, our derivations are based on rather intuitive notions of local expansion…

Probability · Mathematics 2019-03-05 Thomas Sauerwald , Luca Zanetti

We develop a path-based approach to continuous-time random walks on networks with arbitrarily weighted edges. We describe an efficient numerical algorithm for calculating statistical properties of the stochastic path ensemble. After…

Populations and Evolution · Quantitative Biology 2014-08-19 Michael Manhart , Alexandre V. Morozov