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The major advantage of proton therapy over conventional radiotherapy is the dose deposition pattern, enabling precise coverage of the tumour volume while sparing nearby healthy tissues. However, accurate control of the proton beam range…

Medical Physics · Physics 2025-04-01 Magdalena Kołodziej

Proton therapy is nowadays becoming a wide spread clinical practice in cancer therapy and sophisticated treatment planning systems are routinely used to exploit at best the ballistic properties of charged particles. The information on the…

Medical Physics · Physics 2015-05-14 S. Braccini , A. Ereditato , I. Kreslo , U. Moser , C. Pistillo , P. Scampoli , S. Studer

A set of nozzle equipment for proton therapy is now being developed at China Institute of Atomic Energy. To facilitate the off-line commissioning of the whole equipment, a set of ionization chamber signal generation system, the test…

Accelerator Physics · Physics 2025-10-22 Peng Huang , Zhiguo Yin , Tianjian Bian , Shigang Hou , Yang Wang , Tianjue Zhang , Luyu Ji , Lipeng Wen , Xueer Mu , Rui Xiong

A high precision beam monitor system based on silicon carbide PIN sensor is designed for China Spallation Neutron Source 1.6 GeV proton beam to monitor the proton beam fluence.The concept design of the beam monitor system is finished…

A proton irradiation site for silicon detectors has been developed and commissioned at the Bonn Isochronous Cyclotron. The accelerator provides 14 MeV proton beams of up to 1 $\mu$A at beam widths of a few mm to the setup. Devices Under…

Instrumentation and Detectors · Physics 2024-05-07 Pascal Wolf , Dennis Sauerland , Reinhard Beck , Jochen Dingfelder

China's first proton test beam facility, named the High-energy Proton-beam Experiment Station (HPES), is currently under construction in campus of CSNS, as part of the CSNS-II project. Utilizing protons slowly extracted from the Rapid…

Objective: To develop and validate an independent Monet Carlo dose calculation engine to support for software verification of treatment planning systems and quality assurance workflow. Method: GATE Monte Carlo toolkit was employed to…

Medical Physics · Physics 2021-07-27 A. Asadi , A. Akhavanallaf , S. A. Hosseini , N. vosoughi , H. Zaidi

Ion beam therapy has become a frequently applied form of cancer therapy over the last years. The advantage of ion beam therapy over conventional radiotherapy using photons is the strongly localized dose deposition, leading to a reduction of…

Instrumentation and Detectors · Physics 2020-07-28 F. Ulrich-Pur , T. Bergauer , A. Burker , S. Hatamikia , A. Hirtl , C. Irmler , S. Kaser , P. Paulitsch , F. Pitters , V. Teufelhart

In this work, we propose a novel technique for in-vivo proton therapy range verification. This technique makes use of a small hadron tumour marker, $^{92}$Mo, implanted at a short known distance from the clinical treatment volume. Signals…

Purpose: The purpose of this work was to provide a flexible platform for FLASH research with protons by adapting a former clinical pencil beam scanning gantry to irradiations with ultrahigh dose rates. Methods: PSI Gantry 1 treated patients…

A proton pencil beam is associated with a surrounding low-dose envelope, originating from nuclear interactions. It is important for treatment planning systems to accurately model this envelope when performing dose calculations for pencil…

Medical Physics · Physics 2015-11-30 David C. Hall , Anastasia Makarova , Harald Paganetti , Bernard Gottschalk

Treatment planning systems at proton-therapy centres generally use X-ray computed tomography (CT) as primary imaging technique to infer the proton treatment doses to tumour and healthy tissues. However, proton stopping powers in the body,…

We study proton acceleration from a foil target with a transversely varying density using multi-dimensional Particle-in-Cell (PIC) simulations. In order to reduce electron heating and deformation of the target, circularly polarized Gaussian…

Plasma Physics · Physics 2015-05-13 T. P. Yu , M. Chen , A. Pukhov

A number of particle physics experiments are being proposed as part of the Department of Energy HEP Intensity Frontier. Many of these experiments will utilize megawatt level proton beams onto targets to form secondary beams of muons, kaons…

Accelerator Physics · Physics 2012-10-05 Victor E. Scarpine

Objective. The objective of the presented study was to evaluate the feasibility of a coded-mask (CM) gamma camera for real-time range verification in proton therapy, addressing the need for a precise and efficient method of treatment…

Objective. Prompt-gamma imaging encompasses several approaches for online monitoring of beam range or deposited dose distribution in proton therapy. We test one of the imaging techniques - a coded mask approach - both experimentally and via…

The Beam Dump Facility (BDF) is a planned fixed-target installation in CERN's North Area, set to start operating in 2031. A proton beam of 400 GeV/c will be delivered in 1 s pulses of 4e13 protons every 7.2 s, amounting to 4e19 protons on…

Intensity-modulated proton therapy (IMPT) employs proton radiation rather than conventional X-rays to treat cancerous tumors. This approach offers significant advantages by minimizing the radiation exposure of surrounding healthy tissue,…

We have used an inexpensive 3D printer mounting an inexpensive pre-irradiated silicon diode to measure the 2D dose distribution of a small (approximately 10mm FWHM) proton beam. z was measured with high resolution whereas x was changed on a…

Instrumentation and Detectors · Physics 2019-08-13 Ethan W. Cascio , Bernard Gottschalk

The High Intensity Proton Accelerator (HIPA) cyclotron at the Paul Scherrer Institut (PSI) delivers 590 MeV CW proton beam with a maximum power of 1.42 MW. After extraction, the beam is transferred in a 120 m long channel towards two target…

Accelerator Physics · Physics 2022-11-23 M. Haj Tahar , D. Kiselev , A. Knecht , D. Laube , D. Reggiani , J. Snuverink