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Automated social behaviour analysis of mice has become an increasingly popular research area in behavioural neuroscience. Recently, pose information (i.e., locations of keypoints or skeleton) has been used to interpret social behaviours of…

Computer Vision and Pattern Recognition · Computer Science 2025-01-09 Feixiang Zhou , Xinyu Yang , Fang Chen , Long Chen , Zheheng Jiang , Hui Zhu , Reiko Heckel , Haikuan Wang , Minrui Fei , Huiyu Zhou

Weakly electric fish are unique models in Neuroscience allowing experimentalists to access, with non invasive techniques,a central nervous system generated spatio-temporal electric pattern of pulses with roles in at least two complex and…

Quantitative Methods · Quantitative Biology 2012-01-24 Caroline Garcia Forlim , Reynaldo Daniel Pinto

Relating animal behaviors to brain activity is a fundamental goal in neuroscience, with practical applications in building robust brain-machine interfaces. However, the domain gap between individuals is a major issue that prevents the…

Computer Vision and Pattern Recognition · Computer Science 2022-01-20 Semih Günel , Florian Aymanns , Sina Honari , Pavan Ramdya , Pascal Fua

Automatic monitoring of calf behaviour is a promising way of assessing animal welfare from their first week on farms. This study aims to (i) develop machine learning models from accelerometer data to classify the main behaviours of…

Signal Processing · Electrical Eng. & Systems 2024-06-26 Oshana Dissanayake , Sarah E. Mcpherson , Joseph Allyndrée , Emer Kennedy , Pádraig Cunningham , Lucile Riaboff

Calcium imaging is a critical tool for measuring the activity of large neural populations. Much effort has been devoted to developing "pre-processing" tools for calcium video data, addressing the important issues of e.g., motion correction,…

Neurons and Cognition · Quantitative Biology 2020-06-09 Xue-Xin Wei , Ding Zhou , Andres Grosmark , Zaki Ajabi , Fraser Sparks , Pengcheng Zhou , Mark Brandon , Attila Losonczy , Liam Paninski

The nematode Caenorhabditis elegans (C. elegans) serves as an important model organism in a wide variety of biological studies. In this paper we introduce a pipeline for automated analysis of C. elegans imagery for the purpose of studying…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Linfeng Wang , Shu Kong , Zachary Pincus , Charless Fowlkes

Deducing the structure of neural circuits is one of the central problems of modern neuroscience. Recently-introduced calcium fluorescent imaging methods permit experimentalists to observe network activity in large populations of neurons,…

Applications · Statistics 2011-07-22 Yuriy Mishchencko , Joshua T. Vogelstein , Liam Paninski

In this study, we explored the utility of a descriptive and predictive bionetwork model for phospholipase C-coupled calcium signaling pathways, built with non-kinetic experimental information. Boolean models generated from these data yield…

Molecular Networks · Quantitative Biology 2009-12-14 Gaurav Bhardwaj , Christine P. Wells , Reka Albert , Damian B. van Rossum , Randen L. Patterson

Animals move in three dimensions (3D). Thus, 3D measurement is necessary to report the true kinematics of animal movement. Existing 3D measurement techniques draw on specialized hardware, such as motion capture or depth cameras, as well as…

Neurons and Cognition · Quantitative Biology 2021-12-06 Jesse D. Marshall , Tianqing Li , Joshua H. Wu , Timothy W. Dunn

Quantifying human movement (kinematics) and musculoskeletal forces (kinetics) at scale, such as estimating quadriceps force during a sit-to-stand movement, could transform prediction, treatment, and monitoring of mobility-related…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Selim Gilon , Emily Y. Miller , Scott D. Uhlrich

Animals adjust their behavioral response to sensory input adaptively depending on past experiences. The flexible brain computation is crucial for survival and is of great interest in neuroscience. The nematode C. elegans modulates its…

Neurons and Cognition · Quantitative Biology 2024-02-26 Kevin S. Chen , Anuj K. Sharma , Jonathan W. Pillow , Andrew M. Leifer

Effective organismal behavior responds appropriately to changes in the surrounding environment. Attaining this delicate balance of sensitivity and stability is a hallmark of the animal kingdom. By studying the locomotory behavior of a…

Biological Physics · Physics 2021-07-08 Matthew S. Bull , Vivek N. Prakash , Manu Prakash

Motion correction is the first in a pipeline of algorithms to analyze calcium imaging videos and extract biologically relevant information, for example the network structure of the neurons therein. Fast motion correction would be especially…

Computer Vision and Pattern Recognition · Computer Science 2015-06-22 Alexander Dubbs , James Guevara , Darcy S. Peterka , Rafael Yuste

As a vital cognitive function of animals, the navigation skill is first built on the accurate perception of the directional heading in the environment. Head direction cells (HDCs), found in the limbic system of animals, are proven to play…

Neural and Evolutionary Computing · Computer Science 2021-09-23 Zhenshan Bing , Amir EI Sewisy , Genghang Zhuang , Florian Walter , Fabrice O. Morin , Kai Huang , Alois Knoll

Towards developing effective and efficient brain-computer interface (BCI) systems, precise decoding of brain activity measured by electroencephalogram (EEG), is highly demanded. Traditional works classify EEG signals without considering the…

Signal Processing · Electrical Eng. & Systems 2022-09-19 Yimin Hou , Shuyue Jia , Xiangmin Lun , Ziqian Hao , Yan Shi , Yang Li , Rui Zeng , Jinglei Lv

Calcium dynamics is the highly responsible for intracellular electrical (action potential) and chemical (neurotransmitter) signaling in neuron cell. The Mathematical modeling of calcium dynamics in neurons lead to the reaction diffusion…

Cell Behavior · Quantitative Biology 2013-01-08 Amrita tripathi , Neeru Adlakha

Electroencephalogram (EEG) based brain-computer interface (BCI) systems are useful tools for clinical purposes like neural prostheses. In this study, we collected EEG signals related to grasp motions. Five healthy subjects participated in…

Human-Computer Interaction · Computer Science 2020-05-12 Jeong-Hyun Cho , Ji-Hoon Jeong , Seong-Whan Lee

Deep learning segmentation and fluorescence imaging techniques allow the cellular morphology of living embryos to be constructed spatiotemporally. These development processes involve numerous molecules distributed at the subcellular scale,…

Convolutional Neural Networks (CNNs) have achieved promising results in medical image segmentation. However, CNNs require lots of training data and are incapable of handling pose and deformation of objects. Furthermore, their pooling layers…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Minh Tran , Viet-Khoa Vo-Ho , Ngan T. H. Le

Fiber photometry permits monitoring fluorescent indicators of neural activity in behaving animals. Optical fibers are typically used to excite and collect fluorescence from genetically-encoded calcium indicators expressed by a subset of…