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Nanoparticle-based fluorescent sensors have emerged as a competitive alternative to small molecule sensors, due to their excellent fluorescence-based sensing capabilities. The tailorability of design, architecture, and photophysical…

Applied Physics · Physics 2020-05-19 Anil Chandra , Saumya Prasad , Giuseppe Gigli , Loretta L. del Mercato

Steady-state plasmonic lasing is studied theoretically for a system consisting of many dye molecules arranged regularly around a gold nano-sphere. A three-level model with realistic molecular dissipation is employed to analyze the…

Optics · Physics 2018-01-31 Yuan Zhang , Klaus Mølmer

Nanoparticle (NP) arrays of noble metals strongly absorb light in the visible to infrared wavelengths through resonant interactions between the incident electromagnetic field and the metal's free electron plasma. Such plasmonic interfaces…

Mesoscale and Nanoscale Physics · Physics 2013-09-06 Miriam Israelowitz , Jennifer Amey , Tao Cong , Radhakrishna Sureshkumar

Raman spectroscopy enables non-destructive, label-free molecular analysis with high specificity, making it a powerful tool for biomedical diagnostics. However, its application to biological tissues is challenged by inherently weak Raman…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Mengkun Chen , Sanidhya D. Tripathi , James W. Tunnell

Since Purcell's seminal report 75 years ago, electromagnetic resonators have been used to control light-matter interactions to make brighter radiation sources and unleash unprecedented control over quantum states of light and matter.…

Spatial Fluorescence Cross Correlation Spectroscopy is a rarely investigated version of Fluorescence Correlation Spectroscopy, in which the fluorescence signals from different observation volumes are cross-correlated. In the reported…

Optics · Physics 2008-06-13 Yoann Blancquaert , Jie Gao , Jacques Derouard , Antoine Delon

The use of graphene in surface plasmon resonance sensors, covering a metallic (plasmonic) film, has a number of demonstrated advantages, such protecting the film against corrosion/oxidation and facilitating the introduction of functional…

Mesoscale and Nanoscale Physics · Physics 2022-10-26 Aline dos S. Almeida , D. A. Bahamon , Nuno M. R. Peres , Christiano J. S. de Matos

Strong light-matter interactions enabled by surface plasmons have given rise to a wide range of photonic, optoelectronic and chemical functionalities. In recent years, the interest in this research area has focused on the quantum regime,…

Plasmon-polaritons are among the most promising candidates for next generation optical sensors due to their ability to support extremely confined electromagnetic fields and empower strong coupling of light and matter. Here we propose…

In the last few decades, the development of miniature biological sensors that can detect and measure different phenomena at the nanoscale has led to transformative disease diagnosis and treatment techniques. Among others, biofunctional…

Systems and Control · Computer Science 2017-12-05 Hongzhi Guo , Josep Miquel Jornet , Qiaoqiang Gan , Zhi Sun

Stimulated Raman scattering (SRS) microscopy is a highly sensitive chemical imaging technique. However, the broader application of SRS has been limited by two key challenges: the reliance on low-noise but bulky solid-state laser sources and…

Surface plasmon resonances of metallic nanostructures offer great opportunities to guide and manipulate light on the nanoscale. In the design of novel plasmonic devices, a central topic is to clarify the intricate relationship between the…

Optics · Physics 2019-09-11 Sanghyeon Yu , Habib Ammari

Localized plasmons in metallic nanostructures have been widely used to enhance nonlinear optical effects due to their ability to concentrate and enhance light down to extreme-subwavelength scales. As alternatives to noble metal…

Mesoscale and Nanoscale Physics · Physics 2015-02-24 Joel D. Cox , F. Javier Garcia de Abajo

We demonstrated a highly sensitive, waferscale, highly uniform plasmonic nanomushroom substrate based on plastic for nakedeye plasmonic colorimetry and surface enhanced Raman spectroscopy (SERS). We gave it the name FlexBrite. The dualmode…

All-optical active plasmonic devices are of fundamental importance for designing efficient nanophotonic circuits. We theoretically propose and numerically investigate an active plasmonic device made up of a nonlinear epsilon-near-zero…

Optics · Physics 2013-05-29 Alessandro Ciattoni , Carlo Rizza , Elia Palange

Fluorescence is one of the most widely used techniques in biological sciences. Its exceptional sensitivity and versatility make it a tool of first choice for quantitative studies in biophysics. The concept of phasors, originally introduced…

Biomolecules · Quantitative Biology 2025-02-21 Alvaro A. Recoulat Angelini , Leonel Malacrida , F. Luis Gonzalez Flecha

Identifying pathogens in complex samples such as blood, urine, and wastewater is critical to detect infection and inform optimal treatment. Surface-enhanced Raman spectroscopy (SERS) and machine learning (ML) can distinguish among multiple…

Localized surface plasmons can confine light within a deep-subwavelength volume comparable to the scale of atoms and molecules, enabling ultrasensitive responses to near-field variations. On the other hand, this extreme localization also…

Imaging mass spectrometry (IMS) is a powerful tool for untargeted, highly multiplexed molecular mapping of tissue in biomedical research. IMS offers a means of mapping the spatial distributions of molecular species in biological tissue with…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Yijie Zhang , Luzhe Huang , Nir Pillar , Yuzhu Li , Lukasz G. Migas , Raf Van de Plas , Jeffrey M. Spraggins , Aydogan Ozcan

Plasmonic devices, with their ultra-high integration density and data-carrying capacity comparable to optical devices, are currently a hot topic in the field of nanophotonic devices. Photodetectors, non-volatile memories, and ultra-compact…

Optics · Physics 2024-03-12 Xinghui Liu , Kaili Chang , Jiarong Guo , Mengfei Xue , Ran Zhou , Ke Chen , Jianing Chen