Related papers: Optimal census by quorum sensing
Quantum sensing is commonly described as a constrained optimization problem: maximize the information gained about an unknown quantity using a limited number of particles. Important sensors including gravitational-wave interferometers and…
The regulation of cellular function is often controlled at the level of gene transcription. Such genetic regulation usually consists of interacting networks, whereby gene products from a single network can act to control their own…
In recent quantum algorithmic developments, a feedback-based approach has shown promise for preparing quantum many-body system ground states and solving combinatorial optimization problems. This method utilizes quantum Lyapunov control to…
We derive exact solutions of simplified models for the temporal evolution of the protein concentration within a cell population arbitrarily far from the stationary state. We show that monitoring the dynamics can assist in modeling and…
Auto-regulation, a process wherein a protein negatively regulates its own production, is a common motif in gene expression networks. Negative feedback in gene expression plays a critical role in buffering intracellular fluctuations in…
The density classification (DC) task, a computation which maps global density information to local density, is studied using one-dimensional non-unitary quantum cellular automata (QCAs). Two approaches are considered: one that preserves the…
The proper functioning of multicellular organisms requires the robust establishment of precise proportions between distinct cell-types. This developmental differentiation process typically involves intracellular regulatory and stochastic…
Energy storage is a basic physical process with many applications. When considering this task at the quantum scale, it becomes important to optimise the non-equilibrium dynamics of energy transfer to the storage device or battery. Here, we…
We present an active feedback scheme acting continuously on the state of a quantum gas dispersively coupled to a high-finesse optical cavity. The quantum gas is subject to a transverse pump laser field inducing a self-organization phase…
Growth in confined spaces can drive cellular populations through a jamming transition from a fluid-like state to a solid-like state. Experiments have found that jammed budding yeast populations can build up extreme compressive pressures…
Gene expression is a stochastic process governed by the presence of specific transcription factors. Here we study the dynamics of gene expression in the presence of feedback, where a gene regulates its own expression. The nonlinear coupling…
We show how one may analytically compute the stationary density of the distribution of molecular constituents in populations of cells in the presence of noise arising from either bursting transcription or translation, or noise in…
Cooperative effects in neural networks appear because a neuron fires only if a minimal number $m$ of its inputs are excited. The multiple inputs requirement leads to a percolation model termed {\it quorum percolation}. The connectivity…
Living organisms rely on molecular networks, such as gene circuits and signaling pathways, for information processing and robust decision-making in crowded, noisy environments. Recent advances show that interacting biomolecules…
Many modern biological assays, including RNA sequencing, yield integer-valued counts that reflect the number of molecules detected. These measurements are often not at the desired resolution: while the unit of interest is typically a single…
We propose a simple feedback-control scheme for adiabatic quantum computation with superconducting flux qubits. The proposed method makes use of existing on-chip hardware to monitor the ground-state curvature, which is then used to control…
To control a quantum system via feedback, we generally have two options in choosing control scheme. One is the coherent feedback, which feeds the output field of the system, through a fully quantum device, back to manipulate the system…
The effectiveness of measurement-based feedback control (MBFC) protocols is hampered by the presence of measurement noise, which affects the ability to accurately infer the underlying dynamics of a quantum system from noisy continuous…
Biomolecular condensates self-assemble when proteins and nucleic acids spontaneously demix to form droplets within the crowded intracellular milieu. This simple mechanism underlies the formation of a wide variety of membraneless…
Cell decision-making refers to the process by which cells gather information from their local microenvironment and regulate their internal states to create appropriate responses. Microenvironmental cell sensing plays a key role in this…