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Manifold learning techniques have become increasingly valuable as data continues to grow in size. By discovering a lower-dimensional representation (embedding) of the structure of a dataset, manifold learning algorithms can substantially…

Neural and Evolutionary Computing · Computer Science 2020-01-31 Andrew Lensen , Mengjie Zhang , Bing Xue

We address the problem of estimating topological features from data in high dimensional Euclidean spaces under the manifold assumption. Our approach is based on the computation of persistent homology of the space of data points endowed with…

Machine Learning · Statistics 2023-01-23 Ximena Fernández , Eugenio Borghini , Gabriel Mindlin , Pablo Groisman

While the existence of low-dimensional embedding manifolds has been shown in patterns of collective motion, the current battery of nonlinear dimensionality reduction methods are not amenable to the analysis of such manifolds. This is mainly…

Numerical Analysis · Mathematics 2017-07-21 Kelum Gajamannage , Sachit Butail , Maurizio Porfiri , Erik M. Bollt

An Important tool in the field topological data analysis is known as persistent Homology (PH) which is used to encode abstract representation of the homology of data at different resolutions in the form of persistence diagram (PD). In this…

Image and Video Processing · Electrical Eng. & Systems 2022-07-13 Aras Asaad , Dashti Ali , Taban Majeed , Rasber Rashid

Persistent homology is a relatively new tool often used for \emph{qualitative} analysis of intrinsic topological features in images and data originated from scientific and engineering applications. In this paper, we report novel…

Biomolecules · Quantitative Biology 2014-12-09 Kelin Xia , Xin Feng , Yiying Tong , Guo Wei We

Topological Data Analysis (TDA), a relatively new field of data analysis, has proved very useful in a variety of applications. The main persistence tool from TDA is persistent homology in which data structure is examined at many scales.…

Algebraic Topology · Mathematics 2021-09-21 Megan Johnson , Jae-Hun Jung

Identifying molecular signatures from complex disease patients with underlying symptomatic similarities is a significant challenge in the analysis of high dimensional multi-omics data. Topological data analysis (TDA) provides a way of…

Genomics · Quantitative Biology 2024-04-23 Davide Gurnari , Aldo Guzmán-Sáenz , Filippo Utro , Aritra Bose , Saugata Basu , Laxmi Parida

Magnitude homology is an emerging framework that captures the intrinsic topological and geometric features of metric spaces, demonstrating significant potential for topoplogical data analysis and geometric data analysis. This work…

Algebraic Topology · Mathematics 2026-01-08 Wanying Bi , Hongsong Feng , Jingyan Li , Jie Wu

Persistent homology is a mathematical tool used for studying the shape of data by extracting its topological features. It has gained popularity in network science due to its applicability in various network mining problems, including…

Algebraic Topology · Mathematics 2023-06-21 Mehmet Emin Aktas , Thu Nguyen , Rakin Riza , Muhammad Ifte Islam , Esra Akbas

Multidimensional persistence has been proposed to study the persistence of topological features in data indexed by multiple parameters. In this work, we further explore its algebraic complications from the point of view of higher…

Representation Theory · Mathematics 2020-12-07 Mickaël Buchet , Emerson G. Escolar

To gain insight into the mechanisms behind machine learning methods, it is crucial to establish connections among the features describing data points. However, these correlations often exhibit a high-dimensional and strongly nonlinear…

Machine Learning · Computer Science 2025-03-04 Lorenzo Basile , Santiago Acevedo , Luca Bortolussi , Fabio Anselmi , Alex Rodriguez

Topological data analysis uses tools from topology -- the mathematical area that studies shapes -- to create representations of data. In particular, in persistent homology, one studies one-parameter families of spaces associated with data,…

Machine Learning · Computer Science 2020-12-01 Guido Montúfar , Nina Otter , Yuguang Wang

Protein function and dynamics are closely related to its sequence and structure. However prediction of protein function and dynamics from its sequence and structure is still a fundamental challenge in molecular biology. Protein…

Biomolecules · Quantitative Biology 2015-10-06 Zixuan Cang , Lin Mu , Kedi Wu , Kristopher Opron , Kelin Xia , Guo-Wei Wei

Topological Data Analysis (TDA) has been applied with success to solve problems across many scientific disciplines. However, in the setting of a point cloud $X$ sampled from a shape $\mathcal{S}$ of low intrinsic dimension embedded within…

Algebraic Topology · Mathematics 2024-11-18 Jonathan M. Mousley , Paul Bendich

The theory of persistence, which arises from topological data analysis, has been intensively studied in the one-parameter case both theoretically and in its applications. However, its extension to the multi-parameter case raises numerous…

Algebraic Topology · Mathematics 2019-01-29 Nicolas Berkouk

Phase separation mechanisms can produce a variety of complicated and intricate microstructures, which often can be difficult to characterize in a quantitative way. In recent years, a number of novel topological metrics for microstructures…

Numerical Analysis · Mathematics 2020-05-29 Paweł Dłotko , Thomas Wanner

Persistent homology, an algebraic method for discerning structure in abstract data, relies on the construction of a sequence of nested topological spaces known as a filtration. Two-parameter persistent homology allows the analysis of data…

Computational Geometry · Computer Science 2022-07-08 Anway De , Thong Vo , Matthew Wright

Topological data analysis offers a rich source of valuable information to study vision problems. Yet, so far we lack a theoretically sound connection to popular kernel-based learning techniques, such as kernel SVMs or kernel PCA. In this…

Machine Learning · Statistics 2014-12-24 Jan Reininghaus , Stefan Huber , Ulrich Bauer , Roland Kwitt

The protein folding problem must ultimately be solved on all length scales from the atomic up through a hierarchy of complicated structures. By analyzing the stability of the folding process using physics and mathematics, this paper shows…

Biological Physics · Physics 2015-05-28 Walter Simmons , Joel L. Weiner

In this work we investigate the parallel computation of homology using the Mayer-Vietoris principle. We present a two stage approach for parallelizing persistence. In the first stage, we produce a cover of the input cell complex by…

Computational Geometry · Computer Science 2014-07-10 Ryan H. Lewis , Afra Zomorodian