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Related papers: Multidimensional persistence in biomolecular data

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A crucial step in the analysis of persistent homology is the transformation of data into an appropriate topological object (in our case, a simplicial complex). Modern packages for persistent homology often construct Vietoris--Rips or other…

Computational Geometry · Computer Science 2019-09-18 Michelle Feng , Mason A. Porter

One of the most animated themes of multidimensional persistence is the comparison between invariants. The matching distance between persistent Betti numbers functions (or rank invariants), is among the most studied metrics in this context,…

Algebraic Topology · Mathematics 2024-07-09 Patrizio Frosini , Eloy Mósig García , Nicola Quercioli , Francesca Tombari

Topological data analysis provides a multiscale description of the geometry and topology of quantitative data. The persistence landscape is a topological summary that can be easily combined with tools from statistics and machine learning.…

Computational Geometry · Computer Science 2017-07-21 Peter Bubenik , Pawel Dlotko

Hyperuniformity, the suppression of density fluctuations at large length scales, is observed across a wide variety of domains, from cosmology to condensed matter and biological systems. Although the standard definition of hyperuniformity…

Statistical Mechanics · Physics 2024-05-07 Marco Salvalaglio , Dominic J. Skinner , Jörn Dunkel , Axel Voigt

In this paper, we consider topological featurizations of data defined over simplicial complexes, like images and labeled graphs, obtained by convolving this data with various filters before computing persistence. Viewing a convolution…

Algebraic Topology · Mathematics 2024-01-26 Elchanan Solomon , Paul Bendich

The high-dimensional data setting, in which p >> n, is a challenging statistical paradigm that appears in many real-world problems. In this setting, learning a compact, low-dimensional representation of the data can substantially help…

Machine Learning · Computer Science 2018-08-07 Micol Marchetti-Bowick , Benjamin J. Lengerich , Ankur P. Parikh , Eric P. Xing

Topological data analysis provides a set of tools to uncover low-dimensional structure in noisy point clouds. Prominent amongst the tools is persistence homology, which summarizes birth-death times of homological features using data objects…

Methodology · Statistics 2024-02-05 James Matuk , Sebastian Kurtek , Karthik Bharath

We show that persistence-based topology of the 21 cm forest encodes information about Cosmic Dawn that is complementary to traditional amplitude- or correlation-based statistics. Applying topological data analysis to simulated…

Cosmology and Nongalactic Astrophysics · Physics 2026-04-21 Hayato Shimabukuro

Persistent Betti numbers are a major tool in persistent homology, a subfield of topological data analysis. Many tools in persistent homology rely on the properties of persistent Betti numbers considered as a two-dimensional stochastic…

Probability · Mathematics 2024-10-03 Johannes Krebs , Wolfgang Polonik

High order networks are weighted hypergraphs col- lecting relationships between elements of tuples, not necessarily pairs. Valid metric distances between high order networks have been defined but they are difficult to compute when the…

Social and Information Networks · Computer Science 2016-05-04 Weiyu Huang , Alejandro Ribeiro

Topology applied to real world data using persistent homology has started to find applications within machine learning, including deep learning. We present a differentiable topology layer that computes persistent homology based on level set…

Given a metric space $X$ and a subspace $A\subset X$, we prove $A$ can generate various algebraic elements in persistent homology of $X$. We call such elements (algebraic) footprints of $A$. Our results imply that footprints typically…

Algebraic Topology · Mathematics 2022-08-09 Žiga Virk

A persistence module with $m$ discrete parameters is a diagram of vector spaces indexed by the poset $\mathbb{N}^m$. If we are only interested in the large scale behavior of such a diagram, then we can consider two diagrams equivalent if…

Algebraic Topology · Mathematics 2026-05-22 Martin Frankland , Donald Stanley

Protein fold classification is a classic problem in structural biology and bioinformatics. We approach this problem using persistent homology. In particular, we use alpha shape filtrations to compare a topological representation of the data…

Biomolecules · Quantitative Biology 2021-08-23 W. Hamilton , J. E. Borgert , T. Hamelryck , J. S. Marron

Persistent homology probes topological properties from point clouds and functions. By looking at multiple scales simultaneously, one can record the births and deaths of topological features as the scale varies. In this paper we use a…

We propose a method for learning topology-preserving data representations (dimensionality reduction). The method aims to provide topological similarity between the data manifold and its latent representation via enforcing the similarity in…

Machine Learning · Computer Science 2023-05-05 Ilya Trofimov , Daniil Cherniavskii , Eduard Tulchinskii , Nikita Balabin , Evgeny Burnaev , Serguei Barannikov

The existence of characteristic structure, or shape, in complex data sets has been recognized as increasingly important for mathematical data analysis. This realization has motivated the development of new tools such as persistent homology…

Computer Vision and Pattern Recognition · Computer Science 2016-07-12 Sofya Chepushtanova , Michael Kirby , Chris Peterson , Lori Ziegelmeier

Spatial transcriptomics (ST) measures gene expression at a set of spatial locations in a tissue. Communities of nearby cells that express similar genes form \textit{spatial domains}. Specialized ST clustering algorithms have been developed…

Quantitative Methods · Quantitative Biology 2025-11-12 Perry Beamer , Zixuan Cang

Recent years have witnessed a fast growth in mathematical artificial intelligence (AI). One of the most successful mathematical AI approaches is topological data analysis (TDA) via persistent homology (PH) that provides explainable AI (xAI)…

General Topology · Mathematics 2025-10-27 Yiming Ren , Guowei Wei

We start with a simple introduction to topological data analysis where the most popular tool is called a persistent diagram. Briefly, a persistent diagram is a multiset of points in the plane describing the persistence of topological…

Statistics Theory · Mathematics 2017-06-28 Christophe Biscio , Jesper Møller
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