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We outline some basics of imaging using both fully-coherent and partially-coherent X-ray beams, with an emphasis on phase-contrast imaging. We open with some of the basic notions of X-ray imaging, including the vacuum wave equations and the…

Image and Video Processing · Electrical Eng. & Systems 2021-11-16 David M. Paganin , Daniele Pelliccia

Material decomposition in X-ray imaging uses the energy-dependence of attenuation to virtually decompose an object into specific constituent materials. X-ray phase contrast imaging is a developing technique that can enhance image contrast…

Tracing the motion of electrons has enormous relevance to understanding ubiquitous phenomena in ultrafast science, such as the dynamical evolution of the electron density during complex chemical and biological processes. Scattering of…

Atomic Physics · Physics 2013-03-28 Gopal Dixit , Jan Malte Slowik , Robin Santra

The increasingly demand for machining accuracy and product quality excites a great interest in high-resolution non-destructive testing (NDT) methods, but spatial resolution of conventional high-energy computed tomography (CT) is limited to…

Low image contrast is a major limitation in transmission electron microscopy, since samples with low atomic number only weakly phase-modulate the illuminating electron beam, and beam-induced sample damage limits the usable electron dose.…

Instrumentation and Detectors · Physics 2024-03-19 Jeremy J. Axelrod

When a high-contrast ultra-relativistic laser beam enters a micro-sized plasma waveguide, the pulse energy is coupled into waveguide modes, which remarkably modifies the interaction of electrons and electromagnetic wave. The electrons that…

Plasma Physics · Physics 2016-08-03 Longqing Yi , Alexander Pukhov , Baifei Shen

Phase-contrast X-ray imaging can improve the visibility of weakly absorbing objects (e.g. soft tissues) by an order of magnitude or more compared to conventional radiographs. Previously, it has been shown that combining phase retrieval with…

Modern microscopy techniques are developing towards high-resolution imaging, and tremendous progress has been made in past decades; however, the imaging of individual biological macromolecules at atomic resolution using short-wavelength…

Optics · Physics 2022-01-12 Tatiana Latychevskaia

Investigating the structure of matter at the nanoscale non destructively is a key capability enabled by X-ray imaging. One of the most powerful nano-imaging methods is X-ray ptychography, a coherent diffraction imaging technique that has…

Low dose, high contrast x-ray imaging is of general interest in medical diagnostic applications. X-ray Mach-Zehnder interferometers using collimated synchrotron beams demonstrate the highest levels of phase contrast under a given exposure…

Imaging with hard x-rays is an invaluable tool in medicine, biology, materials science, and cultural heritage. Propagation-based x-ray phase-contrast imaging and tomography have been mostly used to resolve micrometer-scale structures inside…

Image and Video Processing · Electrical Eng. & Systems 2025-06-02 Margie P. Olbinado , David M. Paganin , Yin Cheng , Alexander Rack

A new scheme for bright hard x-ray emission from laser wakefield electron accelerator is reported, where pure nitrogen gas is adopted. Intense Betatron x-ray beams are generated from ionization injected K-shell electrons of nitrogen into…

An optical microscope enables image-based findings and diagnosis on microscopic targets, which is indispensable in many scientific, industrial and medical settings. Majority of microscope users are accustomed to standard benchtop…

Optics · Physics 2025-05-06 Keiichiro Toda , Miu Tamamitsu , Ryoichi Horisaki , Takuro Ideguchi

In the cavitation regime of plasma-based accelerators, a population of high-energy electrons tailing the driver can undergo betatron motion. The motion results in X-ray emission, but the brilliance and photon energy are limited by the…

Plasma Physics · Physics 2015-05-01 J. P. Palastro , D. Kaganovich , D. Gordon

Detection of phase variations across optically transparent samples is often a difficult task. We propose and demonstrate a compact, lightweight and low cost quantitative phase contrast imager. Light diffracted from a pinhole is incident on…

The spectrum of laser-plasma generated X-rays is very important, it characterizes electron dynamics in plasma and is basic for applications. However, the accuracies and efficiencies of existing methods to diagnose the spectrum of…

Instrumentation and Detectors · Physics 2021-09-03 Jiaxing Wen , Minghai Yu , Yuchi Wu , Ming Zeng , Bo Zhang , Jirong Cang , Yuge Zhang , Ge Ma , Yue Yang , Wenbo Mo , Zongqing Zhao

Laser-driven compact particle accelerators can provide ultrashort pulses of broadband X-rays, well suited for undertaking X-ray absorption spectroscopy measurements on a femtosecond timescale. Here the Extended X-ray Absorption Fine…

We show how bright, fully coherent, hard x-ray beams can be generated through nonlinear upconversion of femtosecond laser light. By using longer-wavelength mid-infrared driving lasers of moderate peak intensity, full phase matching of the…

We report the LWFA driven X-ray sources development at ELI beamlines. ELI Gammatron beamline provides X-ray pulses of energies from 1-100 keV in betatron scheme, and up to a MeV in Compton scheme. A state-of-the-art Ti:Sa diode-pumped HAPLS…

Plasma Physics · Physics 2022-02-11 U. Chaulagain , M. Lamač , M. Raclavský , S. Karatodorov , J. Nejdl , S. V. Bulanov

Sub-angstrom spatial resolution of electron density coupled with sub-femtosecond temporal resolution is required to directly observe the dynamics of the electronic structure of a molecule after photoinitiation or some other ultrafast…