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High-intensity X-ray sources are essential diagnostic tools for science, technology and medicine. Such X-ray sources can be produced in laser-plasma accelerators, where electrons emit short-wavelength radiation due to their betatron…

Plasma Physics · Physics 2022-03-16 Vojtěch Horný , Miroslav Krůs , Tünde Fülop

X-ray devices are far superior to optical ones for providing nanometre spatial and attosecond temporal resolutions. Such resolution is indispensable in biology, medicine, physics, material sciences, and their applications. A bright…

X-ray phase-contrast imaging (XPCI) is a versatile technique with wide-ranging applications, particularly in the fields of biology and medicine. Where X-ray absorption radiography requires high density ratios for effective imaging, XPCI is…

We propose an imaging system and methodology for mapping soft-tissue samples in three dimensions, with micron-scale and isotropic spatial resolution, with low-concentrations as well as in the absence of heavy metal staining. We used hard…

Instrumentation and Detectors · Physics 2023-12-21 Michela Esposito , Nicole Schieber , Alessandro Olivo , Yannick Schwab , Marco Endrizzi

A setup of a unique x-ray source is put forward employing a relativistic electron beam interacting with two counter-propagating laser pulses in the nonlinear few-photon regime. In contrast to Compton scattering sources, the envisaged x-ray…

Accelerator Physics · Physics 2022-01-19 Q. Z. Lv , E. Raicher , C. H. Keitel , K. Z. Hatsagortsyan

X-ray microtomography at synchrotron sources is fundamentally limited by the high radiation dose applied to the samples, which restricts investigations to non-native tissue states and thereby compromises the biological relevance of the…

These tutorials introduce some basics of imaging with coherent X-rays, focusing on phase contrast. We consider the transport-of-intensity equation, as one particular method for X-ray phase contrast imaging among many, before passing on to…

Image and Video Processing · Electrical Eng. & Systems 2019-02-28 David M. Paganin , Daniele Pelliccia

Compact laboratory-scale X-ray sources still rely on the same fundamental principles as in the first X-ray tubes developed more than a century ago. In recent years, significant research and development have focused on large-scale X-ray…

We show that electron betatron resonance acceleration by an ultra-intense ultra-short laser pulse in a near critical density plasma works as a high-brightness gamma-ray source. Compared with laser plasma X-ray sources in under-dense plasma,…

Accelerator Physics · Physics 2013-10-24 B. Liu , H. Y. Wang , D. Wu , J. Liu , C. E. Chen , X. Q. Yan , X. T. He

Bright sources of high-energy X-rays and electrons are indispensable tools in advanced imaging. Yet, current laser-driven systems typically support only single-modality imaging, require complex infrastructure, or operate at low repetition…

We demonstrate X-ray phase contrast microscopy performed at the European X-ray Free-Electron Laser sampled at 1.128 MHz rate. We have applied this method to image stochastic processes induced by an optical laser incident on water-filled…

X-ray microtomography is a versatile tool allowing the measurement of the 3D structure of optically thick samples. As a non-destructive technique, it is readily adapted to 4D imaging, where a sample can be monitored over time, and…

Instrumentation and Detectors · Physics 2025-12-17 Harry Allan , Tom Partridge , Joseph Jacob , Marco Endrizzi

Propagation-based phase-contrast X-ray imaging is a promising technique for in~vivo medical imaging, offering lower radiation doses than traditional attenuation-based imaging. Previous studies have focused on X-ray energies below 50 keV for…

Exploring and understanding ultrafast processes at the atomic level is a scientific challenge. Femtosecond X-ray Absorption Spectroscopy (XAS) is an essential experimental probing technic, as it can simultaneously reveal both electronic and…

Betatron x-ray source from laser plasma interaction combines high brightness, few femtosecond duration and broad band energy spectrum. However, despite these unique features the Betatron source has a crippling drawback preventing its use…

Bright betatron x-ray has been generated using an Ar clustering gas jet target irradiated with a 3 TW ultra-high contrast laser. The measured emission flux with photon energy > 2.4 keV reaches 2\times10^8 photons/shot. It is ten-fold…

The x-ray emission in laser-plasma accelerators can be a powerful tool to understand the physics of relativistic laser-plasma interaction. It is shown here that the mapping of betatron x-ray radiation can be obtained from the x-ray beam…

Phase Contrast Imaging (PCI), Dark-Field (DF) and Directional Dark-Field (DDF) imaging are recent X-ray imaging modalities that have demonstrated their interest by providing access to information and contrasts different from those provided…

Image and Video Processing · Electrical Eng. & Systems 2023-04-25 Clara Magnin , Laurene Quenot , Sylvain Bohic , Dan Mihai Cenda , Manuel Fernández Martínez , Blandine Lantz , Bertrand Faure , Emmanuel Brun

High-resolution x-ray tomography is a common technique for biomedical research using synchrotron sources. With advancements in laboratory x-ray sources, an increasing number of experiments can be performed in the lab. In this paper, the…

Instrumentation and Detectors · Physics 2024-08-23 Till Dreier , Robin Krüger , Gustaf Bernström , Karin Tran-Lundmark , Isabel Gonçalves , Martin Bech

Holographic coherent X-ray imaging enables nanoscale imaging of biological cells and tissues, rendering both phase and absorption contrast, i.e. real and imaginary parts of the refractive index. Unlike the standard model, which assumes a…

Analysis of PDEs · Mathematics 2026-05-29 Thorsten Hohage , Milad Karimi , Björn Müller